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Öğe Chemical composition, antimicrobial and antioxidant properties of Thymus eigii M. Zohary & P. H. Davis essential oil(2010) Azaz A.D.; Kucukbay Z.; Celen S.; Kuyumcu E.; Yildiz B.The family Lamiaceae is represented by 45 genera, 546 species and 730 taxa in Turkey. The genus Thymus is represented in Turkey by 38 species; the ratio of endemism in the genus is 53%. Thymus eigii samples collected from Hatay were subjected to hydrodistillation to yield essential oils that were subsequently analysed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS). The main constituents of the oils were identified and antimicrobial and antioxidant bioassays were applied. The T.eigii white flowers oil contained carvacrol (43.63%), p-cymene (20.55 %) and thymol (16.06%); T.eiigi with purple flowers oil contained geranyl acetate (15.66 %), p-cymene (14.62%) and thymol (11.48%) as the main components. All tested microorganisms were inhibited by the essential oil samples. Antioxidant activity was tested using the 2,2-diphenyl-l-picrylhydrazyl (DPPH) radical-scavenging method. The antioxidant activity of the tested essential oils were slightly lower than butylated hydroxyanisole (BHA) and so the essential oils can be considered effective natural antioxidants. © Essential Oil Resource Consultants. All rights reserved.Öğe Serum levels of selenium, zinc and copper in patients with coronary artery ectasia(2007) Kosar F.; Taskapan C.; Kucukbay Z.BACKGROUND: It is well established that the deficiency of trace elements may lead to oxidative stress in many tissues. Several studies have shown that the deficiency of trace elements may play a role in the pathogenesis of various heart diseases, including coronary artery disease. This study was designed to determine the serum levels of trace elements, such as selenium, zinc, and copper, in patients with isolated coronary artery ectasia and to confirm previously documented changes in the trace element status in coronary artery disease. It also investigated the relationship between the level of trace elements and the extent of ectatic involvement in patients of coronary artery ectasia. METHODS AND RESULTS: The serum selenium, zinc and copper levels were measured in 37 patients of coronary artery ectasia, 56 patients of coronary artery disease and 30 controls. The trace element levels were measured by atomic absorption photometry methods. The serum selenium (Se) and zinc (Zn) levels in both sets of patients were significantly lower than in the control group (Se: 127 ± 10 ?g/L and 126 ± 9 ?g/L vs. 147 ± 12 ?g/L, p < 0.001; Zn: 557 ± 11 ?g/L and 554 ± 13 ?g/L vs. 620 ± 13 ?g/L, p < 0.001). However, the serum copper (Cu) levels were similar in all patients and controls (964 ± 12 ?g/L and 973 ± 14 ?g/L vs. 956 ± 17 ?g/L, p > 0.05). CONCLUSION: These results suggest that coronary artery ectasia is associated with the deficiency of the trace elements selenium and zinc. Thus, these elements may play an important role in the pathogenesis of coronary artery ectasia, as well as in coronary artery disease.Öğe Synthesis of phytochelatins in Helianthus annuus is enhanced by cadmium nitrate(2003) Yurekli F.; Kucukbay Z.Phytochelatins are the principal heavy metal-detoxifying components in plants. To investigate phytochelatin (PHC) production and the importance of these compounds for heavy metal tolerance, sunflower (Helianthus annuus) was exposed to cadmium. The leaves and roots of sunflower plants cultivated in the presence of 15, 25 and 50 ? M Cd(NO3)2 for 3 and 9 days showed increased tolerance to cadmium and contained higher concentrations of phytochelatins. The phytochelatin level was assayed by using HPLC and the Cd level was determined by atomic spectrum analysis.