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Öğe Clinical and pathological characteristics of non-Hodgkin lymphoma patients in eastern Turkey: a single-center study(Pergamon-Elsevier Science Ltd, 2018) Dogan, N. Yildirim; Erkurt, M.; Dogan, A.; Ekinci, O.; Kuku, I.; Kaya, E.[Abstract Not Available]Öğe Clinical and pathological characteristics of non-hodgkin lymphoma patients in eastern turkey: asingle-center study(Pergamon-elsevıer scıence ltd, the boulevard, langford lane, kıdlıngton, oxford ox5 1gb, england, 2018) Dogan, N. Yildirim; Erkurt, M.; Dogan, A.; Ekinci, O.; Kuku, I.; Kaya, E.Öğe DEMOGRAPHICAL AND CLINICAL CHARACTERISTICS OF ELDERLY PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA: A RETROSPECTIVE MULTICENTER STUDY(Ferrata Storti Foundation, 2014) Nizam, I.; Terzi, H.; Korkmaz, S.; Keklik, M.; Kuku, I.; Kaya, E.; Sencan, M.[Abstract Not Available]Öğe Effects of iloprost on bleomycin-induced pulmonary fibrosis in rats compared with methyl-prednisolone(Elsevier Doyma Sl, 2012) Aytemur, Z. Ayfer; Hacievliyagil, S. Savas; Iraz, M.; Samdanci, E.; Ozerol, E.; Kuku, I.; Nurkabulov, Z.Objective: Prostacyclin (PGI2) has been shown to inhibit the expression of pro-inflammatory and pro-fibrotic mediators in pulmonary fibrosis. In this study, we aimed to test the preventive effects of intraperitoneally administered iloprost, a stable PGI2 analog, on bleomycin-induced pulmonary fibrosis in rats and to compare the effects of iloprost with the effects of methylprednisolone, a traditional therapy. Methods: Rats were randomly allocated into four groups: 1. Saline alone (n = 6); 2. Bleomycin + placebo (n = 7); 3. Bleomycin + methyl-prednisolone (n = 7); 4. Bleomycin + iloprost (n = 7). Fibrotic changes in the lungs were demonstrated by analyzing the cellular composition of bronchoalveolar lavage fluid, histological evaluation and lung hydroxyproline content. Results: Fibrosis was made in the lungs of rats by bleomycin experimentally. Fibrosis scores in the methyl-prednisolone and the iloprost groups were significantly lower than in the placebo group (p < 0.05). Furthermore, the score of the iloprost group was significantly lower than the score of the methyl-prednisolone group. The hydroxyproline content was significantly less in the methyl-prednisolone and the iloprost groups (p < 0.05). In the placebo group, the neutrophil percentage in bronchoalveolar lavage was significantly higher than in the other groups, whereas the macrophage percentage in placebo group was significantly lower (p < 0.05). Conclusion: Iloprost has protective effect on the pulmonary fibrosis induced by bleomycin and it may be more effective in decreasing fibrotic changes than methyl-prednisolone. (C) 2011 Sociedade Portuguesa de Pneumologia. Published by Elsevier Espana, S. L. All rights reserved.Öğe EVALUATION OF FEBRILE NEUTROPENIC EPISODES IN ACUTE MYELOID LEUKEMIA PATIENTS(Ferrata Storti Foundation, 2013) Comert, M.; Aydogdu, I.; Kaya, E.; Yetkin, F.; Erkurt, M.; Kuku, I.[Abstract Not Available]Öğe MEAN CORPUSCULAR VOLUME CAN BE AN EARLY PREDICTOR FOR MOLECULAR RESPONSE IN CHRONIC PHASE CHRONIC MYELOID LEUKEMIA PATIENTS(Pergamon-Elsevier Science Ltd, 2017) Ozkan, M. Comert; Kaya, E.; Cirik, S.; Kuku, I.; Erkurt, M.[Abstract Not Available]Öğe Relation of basal vitamin D and parathyroid hormone levels to CD34+cell counts in multiple myeloma and lymphoma patients with stem cell mobilization(Pergamon-Elsevier Science Ltd, 2018) Kaya, A.; Kaya, E.; Erkurt, M.; Kuku, I.[Abstract Not Available]Öğe Thrombocytapheresis decreases systolic blood pressure and increases sympatho-vagal balance(Pergamon-Elsevier Science Ltd, 2018) Cakan, P.; Ozgul, M.; Erkurt, M.; Kaya, E.; Yildiz, S.; Kuku, I.[Abstract Not Available]Öğe Thrombocytapheresis decreases systolic blood pressure and increasessympatho-vagal balance(Pergamon-elsevıer scıence ltd, the boulevard, langford lane, kıdlıngton, oxford ox5 1gb, england, 2018) Cakan, P.; Ozgul, M.; Erkurt, M.; Kaya, E.; Yildiz, S.; Kuku, I.Öğe THE TROUBLE THAT HEMATOLOGISTS DEALING WITH: VARICELLA-ZOSTER AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION(Ferrata Storti Foundation, 2016) Ozkan, M. Comert; Ozen, I. Nizam; Dolasik, I.; Kaya, E.; Erkurt, M. A.; Kuku, I.[Abstract Not Available]