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    Elevated nucleated red blood cell count
    (Sci Printers & Publ Inc, 2006) Üstün, Y; Engin-Üstün, Y; Kaya, E; Meydanli, MM; Kulak, N
    OBJECTIVE: To assess the prevalence and causes of elevated nucleated red blood cell (NRBC) count. STUDY DESIGN: We conducted a 1-year, population based surveillance study that included pregnant women and their infants from our medical center, which serves as a tertiary referral hospital. Outcome measures included NRBC count, gestational age, mode of delivery, birth weight, Apgar scores, cord blood gasses, rate of neonatal intensive care unit admission. Statistical analyses were performed with Mann-Whitney U-test, independent samples t test, chi(2) test, Fisher's exact test and Spearman's correlation test, as appropriate. RESULTS: NRBC count obtained from 423 women had a median of 4 (0-163). A cutoff point of 13.5 for predicting fetal acidosis had the highest combined sensitivity (77.8%) and specificity (84%). Three hundred forty-nine neonates had a NRBC count <= 13.5, whereas 73 had > 13.5. Logistic regression analysis revealed that preeclampsia (OR = 5.9, 95% CI = 2.8-12.3) remained the most prominent risk factor for elevated NRBC count. CONCLUSION: Elevated NRBC appears to be associated with preeclampsia.
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    What should be done with patients who have abnormal GCT but normal GTT?
    (Medimond Publishing Co, 2004) Kafkasli, A; Karabulut, A; Kazezoglu, G; Kulak, N; Koçak, M; Yologlu, S
    The aim of this study is to evaluate the carbonhydrate metabolism in pregnants with abnormal glucose challenge, but normal 100g-3-hour oral glucose tolerance test. Pregnants who were delivered at Ynonu University School of Medicine Department of Obstetrics and Gynecology and meet the criteria included the study. Group 1(n:6) gestational diabetes mellitus, Group 2(n: 8) Type 2 diabetes mellitus, Group 3(n: 10) plasma glucose levels were 140mg/dl f after glucose challenge test, but normal 100g-oral glucose tolerance test, Group 4(n:8) pregnants with normal glucose challenge test and have appropriate-for-gestational-age neonate as control group,Group 5(n:8) pregnants with normal glucose challenge test and have macrosomic neonate were included the study. Maternal blood was collected to evaluate the carbonhydrate metabolism by comparing the IGF-I,II and IGFBP-1,2,3 levels. IGF I-II and IGFBP1,2,3 measurements were done by RIA and IRMA technics respectively. Maternal plasma levels of IGF-II and IGFBP-1, -3 were found to be significantly higher than control group in gestational diabetics, type-2 diabetic pregnants, pregnants with abnormal glucose challenge test but normal 100g-oral tolerance test and pregnants with macrosomic infant (p<0.000, p<0.000, p<0.05, p<0.05).