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  • Küçük Resim
    Öğe
    Radyoterapi almış nazofarenks kanserli olgularda koku duyusunun değerlendirilmesi
    (İnönü Üniversitesi, 2014) Kurnaz Kaplan, Bilge
    Çalışmamızda nazofarenks kanser (NFK) hastalarında radyoterapi (RT) tedavisi sonrası koku duyusunda kayıp oluşup oluşmadığı, oluşuyorsa bunun hastanın yaşam kalitesine etkisinin saptanması amaçlandı. Bu çalışmada NFK sonrasında RT alan 21 hasta ve kontrol grubu olarak sağlıklı 21 gönüllü aldık. Her iki gruba da otonazal koku testleri, yaşam kalitesi ölçeği ve olfaktör bulbus (OB) hacmini ölçmek amacı ile MR görüntüleme uygulandı. Yaptığımız karşılaştırmada her iki grup arasında ortonazal koku testleri ve yaşam kalitesi ölçeği yönünden istatistiksel olarak anlamlı fark saptadık. Ancak olfaktör bulbus hacmi yönünden iki grup arasında anlamlı fark saptamadık.Bu çalışmada olfaktör bulbus hacminin değişmediğini fakat yaşam kalitesi ölçeği ve subjektif koku testleri ile hastaların RT sonrasında koku duyusunda azalma hissettiklerini ve bunun yaşam kalitesini olumsuz yönde etkilediğini bulduk. Bunun sonucunda RT öncesi hastalara tedavi sonrası koku duyusunda azalma olabileceği hakkında bilgi verilmesi gerektiği sonucuna varıldı.
  • Küçük Resim
    Öğe
    A rare case in an adolescent patient with nasal polyps resistant to polypectomy: Samter’s syndrome
    (2021) Kurnaz Kaplan, Bilge; Kaplan, Fatih
    The comorbidity of recurrent nasal polyps, non-steroidal anti-inflammatory drug hypersensitivity and chronic rhinosinusitis is called Samter’s syndrome. It is less common in childhood than in adulthood. Patients first have nasal symptoms and then asthma and non-steroidal anti-inflammatory drug (NSAID) hypersensitivity begin to accompany. For definitive diagnosis, NSAID or aspirin hypersensitivity must be shown with provocation test. In this case report, oral provocation test with ibuprofen was performed on a 17-year-old female patient who had recurrent nasal polyps and chronic rhinosinusitis accompanied by asthma and NSAID hypersensitivity and the test was found to be positive. The patient was diagnosed with Samter’s syndrome and aspirin desensitization was applied. Inhaled steroid, intranasal steroid and montelukast therapies were started. As a conclusion, although it is more common in adults, Samter’s syndrome should also be considered in pediatric patients with recurrent nasal polyp, chronic rhinosinusitis, asthma, and NSAID hypersensitivity.
  • Küçük Resim
    Öğe
    A rare case in an adolescent patient with nasal polyps resistant to polypectomy: Samter’s syndrome
    (2021) Kaplan, Fatih; Kurnaz Kaplan, Bilge
    Abstract: The comorbidity of recurrent nasal polyps, non-steroidal anti-inflammatory drug hypersensitivity and chronic rhinosinusitis is called Samter’s syndrome. It is less common in childhood than in adulthood. Patients first have nasal symptoms and then asthma and non-steroidal anti-inflammatory drug (NSAID) hypersensitivity begin to accompany. For definitive diagnosis, NSAID or aspirin hypersensitivity must be shown with provocation test. In this case report, oral provocation test with ibuprofen was performed on a 17-year-old female patient who had recurrent nasal polyps and chronic rhinosinusitis accompanied by asthma and NSAID hypersensitivity and the test was found to be positive. The patient was diagnosed with Samter’s syndrome and aspirin desensitization was applied. Inhaled steroid, intranasal steroid and montelukast therapies were started. As a conclusion, although it is more common in adults, Samter’s syndrome should also be considered in pediatric patients with recurrent nasal polyp, chronic rhinosinusitis, asthma, and NSAID hypersensitivity.