Yazar "Kurt, Osman" seçeneğine göre listele
Listeleniyor 1 - 20 / 25
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe 6 Şubat 2023 Kahramanmaraş Merkezli Depremlerden Etkilenen Depremzedelerde İntihar Girişimi, Dürtüsellik, Psikolojik Acı ve Depresyonun Araştırılması(2024) Sehlikoğlu, Kerem; Yildiz, Sevler; Kurt, Osman; Sehlikoğlu, Şeyma; Emir, Burcu SırlıerAmaç: 6 Şubat 2023 tarihli Kahramanmaraş merkezli depremlerden etkilenen depremzedelerden inti-har girişimi olan grupta bulunmayı öngören dürtüsellik, psikolojik acı, depresyon ve anksiyete düzeyleri-ni incelemekti. Materyal ve Metod: Ağustos 2023 ile Şubat 2024 arasında, intihar girişiminde bulunan 36 depremzede, bir psikiyatri kliniğinde vaka grubuna dahil edilmek üzere seçildi. Aynı zamanda, vaka grubu ile yaş ve cinsiyet açısından eşleştirilen ve psikiyatrik tanı almamış 36 depremzeden oluşan bir kontrol grubu oluşturuldu. Devamında her bir depremzede yarı yapılandırılmış sosyodemografik ve klinik veri formu, Beck Depresyon Ölçeği (BDÖ), Beck Anksiyete Ölçeği (BAÖ), Psikolojik Acı Ölçeği (PAÖ) ve Barratt Dürtüsellik Ölçeğini (BDÖ) doldurdu. Bulgular: İntihar girişiminde bulunan hastaların %63.9'u kadındı. Vaka grubundaki bireyler, kontrol gru-buna göre depremde daha fazla akraba kaybı yaşadı (p=0,002). Vaka grubunda, plan yapmama alt ölçeği ile BDÖ ve PAÖ arasında pozitif bir korelasyon vardı (sırasıyla r=0,691, p<0,001, r=0,370 p=0,026). İnti-har eyleminin depremle ilgili olup olmadığı açısından analiz edildiğinde, depremle ilgili intiharlarda daha az intihar geçmişi ve yöntem farkı olduğu gözlemlendi (sırasıyla p=0,006, p=0,029). Lojistik regres-yon analizine göre, yüksek PAÖ şiddeti, depremzedelerin intihar girişimi geçmişine sahip olma grubunda yer alacağını öngörmektedir (OR = 1,50, %95 CI: 1,17-1,94, p=0,01). Sonuç: Depresyon, dürtüsellik, anksiyete ve psikolojik acı belirtileri gösteren deprem sonrası hayatta kalanlar, intihar riski açısından yakından izlenmeli ve psikososyal müdahaleler sağlanmalıdır.Öğe Assessing the impact of metalworking exposures on respiratory health: the role of fractional exhaled nitric oxide levels(Taylor & Francis Ltd, 2025) Tiryaki, Huelya Dogan; Issever, Halim; Kucukkelepce, Osman; Gungen, Adil Can; Seker, Nefise; Kurt, OsmanObjectiveThe significance of measuring Fractional Exhaled Nitric Oxide (FeNO) has grown, particularly in monitoring respiratory diseases like asthma. FeNO levels indicate inflammation and a rise in response to respiratory irritants. This study investigates whether repeated exposure to irritants in metal casting and coating leads to respiratory inflammation and assesses the benefits of including FeNO measurement in periodic occupational health screenings.MethodsThis cross-sectional study involved 99 workers aged 18-65 in the foundry and metal coating sectors in the & Idot;kitelli Organized Industrial Zone. The study group included 54 workers exposed to metal dust and fumes, while the control group comprised 45 workers in non-exposure roles (e.g. secretarial, assembly, packaging). Data were collected through face-to-face interviews, recording demographics, smoking habits, symptoms. FeNO levels were measured and analyzed with pulmonary function test parameters.ResultsFeNO levels were significantly higher in the study group compared to the control group (p = 0.02). No significant relationships were found between FeNO levels and age, height, weight, BMI, waist circumference, years of work, or symptom presence, but a significant negative correlation was observed between FeNO levels and FEV1/FVC. Additionally, current smokers had significantly lower FeNO levels compared to those who had quit or never smoked (study, p = 0.014; control, p = 0.011).ConclusionsMonitoring FeNO levels in occupational health assessments may facilitate early intervention and preventive measures, protecting worker health. Incorporating FeNO measurement into periodic screenings could enhance occupational health practices.Öğe ASSESSMENT OF PSYCHOLOGICAL RESPONSES AND RELATED FACTORS OF DISCHARGED PATIENTS WHO HAVE BEEN HOSPITALIZED WITH COVID-19(Medicinska Naklada, 2021) Cansel, Neslihan; Tetik, Burcu Kayhan; Demi, Gulsu Hilal; Kurt, Osman; Evren, Bahri; Yucel, AytacBackground: COVID-19 is the biggest pandemic of the last century. While a large number of cases and mortality rates direct the research to the clinic and prognosis of the disease, the mental health of these patients has recently become a matter of concern. This study aims to predict psychiatric morbidity and possible associated markers in COVID-19 survivors. Subjects and methods: A total of 102 survivors with COVID-19 infection participated in this study. A questionnaire was applied to the participants to evaluate demographic variables, history of comorbid diseases, smoking, loss of a relative due to COVID-19, and environmental attitudes after the discharge. Length of hospitalization, lung findings, intensive care history and treatments were recorded. Psychiatric morbidities were evaluated with General Anxiety Disorder-7, Patient Health Questionnaire-9 and The Results: Anxiety was found in 20.6%, depression in 13.7% based on moderate and above levels, 21.6% had significant PTSD. Female gender, history of psychiatric and comorbid diseases, smoking, perceived discrimination, and lack of long-lasting immunity posed a risk in terms of psychological response. There was a negative correlation between age and depression scores. No relation was found between the duration of hospitalization, presence of lung involvement, receiving intensive care treatment, losing a relative due to COVID-19 and psychological response. Conclusions: On patients treated for COVID-19 infection, psychological response continue after discharge. Mental health support and efforts to reduce stigma among infected subjects can reduce the psychological impact caused by the pandemic.Öğe Can artificial ıntelligence detect the anti-aging effect of rhinoplasty?(Medical Journal Sweden Ab, 2025) Yalcin, Muhammed Zeki; Toplu, Yuksel; Kurt, OsmanBackground: The quest for eternal youth has been a common theme in many cultures for centuries. While we have yet to discover a way to preserve youth eternally, we have made significant progress in understanding the aging process and in developing pharmaceuticals, surgical techniques, and technologies. In addition to rhinoplasty's facial beautification effect, we investigated whether it had a facial anti-aging effect using an artificial intelligence (AI)-based program. We also examined the correlation between patient satisfaction and the anti-aging effect of rhinoplasty. Methods: This study included 244 patients who underwent functional septorhinoplasty (FSRP) between postoperative photographs in our archive were evaluated using an AI-based age analysis program. In addition, the participants evaluated preoperative and postoperative nose satisfaction with the FACE-Q survey in the postoperative period. Results: One hundred two males (41.8%) and 142 females (58.2%) were included in the study. The mean preoperative age determined by the program was 25.9 +/- 6.1, and the mean postoperative age was 25.7 +/- 5.8. Despite the mean follow-up period of the patients was 25.3 +/- 8.7 months, our study showed no significant difference between the mean preoperative and postoperative ages. The mean general satisfaction of the patients increased postoperatively. Conclusion: Despite the average follow-up period, the absence of a significant difference between preoperative and postoperative perceived mean age may be interpreted as a possible anti-aging effect of rhinoplasty. This effect was more prominent in older patients and in women.Öğe Detection of Pancreatic Beta Cell Reserve and Its Relationship with Metabolic Markers and Anthropometric Measurements in Patients with Active Psychotic and Mood Disorders(2024) Gürok, Mehmet Gürkan; Kilinc, Faruk; Kurt, Osman; Afsar Karatepe, Bercem; Ustundag, Bilal; Uslu, Muhammed FuadObjective: In this research, our objective is to explore how pancreatic beta cell reserve is determined and its correlation with metabolic markers among individuals receiving active treatment for psychotic and mood disorders. Materials and Methods: The study included 60 healthy controls and 60 psychiatrically treated patients on regular antipsychotic medication. Insulin, c-peptide, cholesterol, triglyceride, LDL cholesterol, HDL cholesterol, vitamin D, HbA1c, parathormone, prolactin, TSH levels were analyzed after anthropometric measurements of all participants. Results: The Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) value was notably greater in the case group compared to the control group, with a significant difference observed (p=0.041). Triglyceride (TG), Very low density lipoprotein (VLDL), Total cholesterol and Low density lipoprotein (LDL) values of the case group were significantly higher than the control group. During the correlation analysis, a noteworthy positive correlation was identified between weight and BMI, waist circumference, waist-to-neck ratio, waist-to-hip ratio, insulin levels, and c-peptide levels. Conclusion: We believe that individuals with high-risk factors should undergo regular monitoring for conditions such as obesity, insulin resistance, hyperlipidemia, prediabetes, and diabetes, which can be beneficial.Öğe ENHANCING RISK PERCEPTIONS AND KNOWLEDGE IN WOMEN WITH RISK PREGNANCIES: EDUCATIONAL INTERVENTION(Istanbul Univ, Fac Medicine, Publ Off, 2025) Kucukkelepce, Osman; Dogan Tiryaki, Hulya; Kurt, Osman; Bugdayci Yalcin, Bengue Nehir; Oz, ErdoganObjective: We aimed to determine the risk perceptions of women with risky pregnancies. This study aimed to enhance and reevaluate their risk perceptions after providing education abouttheir risks. Material and Methods: This educational intervention study aimed to engage 336 pregnant women out of a 2,664 population with high-risk pregnancies in Adiyaman, T & uuml;rkiye. In total, 444 pregnant women participated in the study. Participants completed the sociodemographic questionnaires, a pregnancy risk perception assessment, and a knowledge assessment related to pregnancy risks. The questionnaires were administered twice: once before the educational intervention and again 2-4 weeks after the intervention, allowing us to measure the effectiveness of the education. Results: After the educational intervention, pregnant women demonstrated a significant increase in both their risk knowledge and risk perception scores (p<0.001). Furthermore, we observed a positive correlation between knowledge scores and age (p<0.001) as well as first gestational age (p<0.001), while a negative correlation was found with gestational age (p=0.003). Additionally, a positive correlation emerged between the risk perception score and age (p=0.008) and the number of obstetrician visits (p=0.024). Conclusion: To enhance the risk perception, it is crucial to provide them with specialised education on this subject. This is imperative because every woman with a high-risk pregnancy is not only vulnerable to maternal mortality but also places her infant ata higher risk of infant mortality.Öğe Evaluation of Adolescents' Status of The FirstStep Health Services Use and Healthy Nutrition Behaviors(2021) Kayhan Tetik, Burcu; Gedik, İsilay; Kurt, OsmanAbstract: Aim: This study aimed to evaluate the status of the first-step health services use, healthy nutrition behaviors in adolescents and investigate their relationships with each other. Methods: One hundred and forty-six adolescents between the ages of 10 and 18 were included in this descriptive study. A survey of 15 questions about the participants' healthy nutritional behaviors, the status of knowing their family physicians, and going to their family physicians for the examination was applied. The obtained data were analyzed using the SPSS 22 package program, and p <0.05 was considered significant. Results: Of the participants, 85.6% went to their family physicians for the examination, the mean age was 16.4±1.6, and 58.9% were girls. Girls' mean scores of healthy nutritional behavior and going to their family physicians for the examination were significantly higher than boys'. In those who were obese and overweight, the rate of knowing their family physicians, the mean score of going to their family physicians for the examination, and healthy nutritional behavior were lower than normal weight. Conclusion: In our study, lower obesity and overweight rates and having a healthier diet were seen in adolescents using primary health care services more. We believe that to eliminate obesity, which has been a significant public health problem today, increasing the rate of using primary health care services for adolescent individuals needs to be increased. We hope that our comments raised herein will encourage other physicians to be more sensitive about this issue and direct patients to primary care more often to receive such services.Öğe Evaluation of Doctors' Knowledge of Rational Laboratory Use, a Descriptive Study from Turkey(Duzce Univ, Fac Medicine, 2021) Kilic, Evrim; Tetik, Burcu Kayhan; Kurt, OsmanObjective: The effects of health expenditures on the economy of countries have become more evident in recent years. Especially unnecessary and inappropriate laboratory tests increase both the cost and the workload. In this study, it was aimed to evaluate the level of knowledge of physicians about rational laboratory use and procedure for frequently ordered tests in clinical practice. Methods: This study was planned to be a descriptive study. A questionnaire based on the current circular about 'Rational Laboratory Use' and including sociodemographic data was applied to physicians working at Turgut Ozal Medical Center. Results: The questionnaire was applied to a total of 400 physicians working in internal medicine and surgical branches. The average age of the physicians was 33.01 +/- 5.97 (min = 22, max = 59) years. The question about order period of blood lipids was answered correctly by 3.3% of physicians, HbA1c by 80.8%, Urea / creatinine by 64.5%, and vitamin D and vitamin B12 was answered by 40% of physicians. On the other hand 85.3% of the physicians were not aware of the rational laboratory test ordering procedure and 94% had not received any training on rational laboratory use. Conclusions: It was found that physicians had insufficient knowledge about rational laboratory use and they did not receive any training about the test procedures. In order to reduce health expenditures, more training on this subject should be organized for physicians and awareness should be raised.Öğe Evaluation of Doctors’ Knowledge of Rational Laboratory Use, a Descriptive Study from Turkey(2021) Kılıç, Evrim; Tetik, Burcu Kayhan; Kurt, OsmanObjective: The effects of health expenditures on the economy of countries have become more evident in recent years. Especially unnecessary and inappropriate laboratory tests increase both the cost and the workload. In this study, it was aimed to evaluate the level of knowledge of physicians about rational laboratory use and procedure for frequently ordered tests in clinical practice. Methods: This study was planned to be a descriptive study. A questionnaire based on the current circular about 'Rational Laboratory Use' and including sociodemographic data was applied to physicians working at Turgut Ozal Medical Center. Results: The questionnaire was applied to a total of 400 physicians working in internal medicine and surgical branches. The average age of the physicians was 33.01 ± 5.97 (min = 22, max = 59) years. The question about order period of blood lipids was answered correctly by 3.3% of physicians, HbA1c by 80.8%, Urea / creatinine by 64.5%, and vitamin D and vitamin B12 was answered by 40% of physicians. On the other hand 85.3% of the physicians were not aware of the rational laboratory test ordering procedure and 94% had not received any training on rational laboratory use. Conclusions: It was found that physicians had insufficient knowledge about rational laboratory use and they did not receive any training about the test procedures. In order to reduce health expenditures, more training on this subject should be organized for physicians and awareness should be raised.Öğe Evaluation of Oxidative Stress and Endothelial Dysfunction in COVID-19 Patients(Mdpi, 2024) Berber, Nurcan Kirici; Kurt, Osman; Geckil, Ayseguel Altintop; Erdem, Mehmet; Kiran, Tugba Raika; Otlu, Onder; Ecin, Seval MuzeyyenBackground and Objectives: Heat shock proteins (HSPs) are stress proteins. The endogenous nitric oxide (NO) synthase inhibitor asymmetric dimethyl arginine (ADMA) is a mediator of endothelial dysfunction. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus causes endothelial dysfunction and coagulopathy through severe inflammation and oxidative stress. Using these markers, we analyzed the prognostic value of serum ADMA and HSP-90 levels for early prediction of severe coronavirus disease (COVID-19) patients. Materials and Methods: A total of 76 COVID-19 patients and 35 healthy control subjects were included in this case-control study. COVID-19 patients were divided into two groups: mild and severe. Results: Serum ADMA and HSP-90 levels were significantly higher in the COVID-19 patients compared to the control subjects (p < 0.001). Additionally, serum ADMA and HSP-90 levels were determined to be higher in a statistically significant way in severe COVID-19 compared to mild COVID-19 (p < 0.001). Univariable logistic regression analysis revealed that ADMA and HSP-90, respectively, were independent predictors of severe disease in COVID-19 patients (ADMA (OR = 1.099, 95% CI = 1.048-1.152, p < 0.001) and HSP-90 (OR = 5.296, 95% CI = 1.719-16.316, p = 0.004)). When the cut-off value for ADMA was determined as 208.94 for the prediction of the severity of COVID-19 patients, the sensitivity was 72.9% and the specificity was 100% (AUC = 0.938, 95%CI = 0.858-0.981, p < 0.001). When the cut-off value for HSP-90 was determined as 12.68 for the prediction of the severity of COVID-19 patients, the sensitivity was 88.1% and the specificity was 100% (AUC = 0.975, 95% CI= 0.910-0.997, p < 0.001). Conclusions: Increased levels of Heat shock proteins-90 (HSP-90) and ADMA were positively correlated with increased endothelial damage in COVID-19 patients, suggesting that treatments focused on preventing and improving endothelial dysfunction could significantly improve the outcomes and reduce the mortality rate of COVID-19. ADMA and HSP-90 might be simple, useful, and prognostic biomarkers that can be utilized to predict patients who are at high risk of severe disease due to COVID-19.Öğe Exploring Post-Traumatic Stress Disorder and Hygiene Patterns in Adiyaman, Türkiye after the Türkiye and Syria Earthquake(Cambridge Univ Press, 2025) Kucukkelepce, Osman; Konyalioglu, Fatma Sena; Kurt, Osman; Oz, ErdoganObjectives On February 6, 2023, seismic activity struck Kahramanmara & scedil;, with earthquakes of magnitudes 7.7 and 7.6. The study aimed to determine the effect of the presence of PTSD and its scores on hygiene behaviors.Methods This cross-sectional study was conducted in Ad & imath;yaman, T & uuml;rkiye, between September and October 2023. The study population comprised individuals aged 18 and above who had experienced the earthquake. The PTSD Checklist-Civilian (PCL-C) scale was used to evaluate PTSD, and the Hygiene Inventory was used to evaluate the participants' hygiene behaviors.Results Females, those with lower levels of education, the unemployed, singles, those living in tents, individuals who lost a loved one in the earthquake, and those with PTSD had worse hygiene behaviors compared to other groups. In the multivariate model of linear regression analysis of hygiene total score, only the PTSD score retained its predictive significance for hygiene behavior. More than 50% of the participants had scores meeting PTSD. The total PTSD score and the prevalence of PTSD among women was notably greater.Conclusions Mental health plays a pivotal role in shaping individuals' hygiene practices and behavior patterns post-disaster. Swift implementation of mental health interventions is crucial for the prevention of behavioral pathologies.Öğe Exploring the Relationship between Post-Traumatic Stress and Job-Related Stress among Nurses in the Aftermath of Kahramanmaraş Earthquakes in Adıyaman: A Cross-Sectional Study(Cambridge Univ Press, 2025) Kurt, Osman; Konyalioglu, Fatma Sena; Kucukkelepce, Osman; Oguzoncul, Ayse FerdaneObjectives This study aims to investigate the relationship between post-traumatic stress disorder (PTSD) and job-related stress among nurses working in both central and district areas of Ad & imath;yaman following the earthquake. Additionally, we assess potential risk factors influencing both PTSD and job-related stress. Methods This cross-sectional study involved 332 nurses. The study considered several independent variables, including age, gender, marital status, place of residence, experience of family loss due to the earthquake, and workplace location. The dependent variables for the study were identified as post-traumatic stress disorder and job stress. Results Of the nurses surveyed, 69% showed symptoms of post-traumatic stress disorder. Notably, higher job stress scale scores were identified among women (P = 0.028), married individuals (P = 0.005), those with children (P < 0.001), those who were in Ad & imath;yaman during the earthquake (P < 0.001), and those who experienced family loss due to the earthquake (P < 0.001). Furthermore, a significant positive correlation was observed between PTSD scores and job stress scores (r = 0.599; P < 0.001). Results Of the nurses surveyed, 69% showed symptoms of post-traumatic stress disorder. Notably, higher job stress scale scores were identified among women (P = 0.028), married individuals (P = 0.005), those with children (P < 0.001), those who were in Ad & imath;yaman during the earthquake (P < 0.001), and those who experienced family loss due to the earthquake (P < 0.001). Furthermore, a significant positive correlation was observed between PTSD scores and job stress scores (r = 0.599; P < 0.001). Conclusions Given the bidirectional impact of PTSD and job stress, prompt and comprehensive interventions are essential for safeguarding nurses' mental health and professional capacity following major events. These interventions should also consider other risk factors, such as female gender or experiencing a family loss.Öğe Geleceğin Hekimlerinin ve Eczacılarının Eğitimlerinin İlk Yılında Akılcı İlaç Kullanımı Konusundaki Farkındalıkları(İnönü Üniversitesi, 2024) Kurt, Osman; Yılmaz Bozoğlan, MerveDünya Sağlık Örgütü, tüm ilaçların yarısından fazlasının hastaya uygun olmadan reçetelendiği veya hasta tarafından eczaneden tedarik edildiğini, reçeteli veya reçetesiz olarak eczaneden edinilmiş bu ilaçların da hastaların yarısı tarafından doğru bir şekilde kullanmadığını bildirmiştir. Çalışmanın amacı ilerde ilaçları reçete edecek veya reçetedeki ilaçları hastaya ulaştıracak sağlık çalışanları olma eğitimlerinin ilk yılında tıp, diş hekimliği ve eczacılık fakülteleri öğrencilerinin Akılcı İlaç Kullanımı (AİK) bilgi ve davranışlarını değerlendirmektir. Gereç ve Yöntem: Bir internet tarayıcısının çevrimiçi anketlerinden faydalanılarak sunulan ankette önce cinsiyet ve yaş gibi demografik bilgiler alınmış, sonra AİK bilgi ve davranışlarını gösterecek sorular sorulmuş ve son olarak AİK ölçeği sorularının yanıtlanması beklenmiştir. 3 ay süre ile açık tutulan ankette toplamda 359 tıp, diş hekimliği ve eczacılık öğrencisine ulaşılmıştır. AİK ölçeğinde toplam puanı 35 üzeri olanlar, AİK konusunda başarılı olarak değerlendirilmiştir. Bulgular: Katılımcıların 246’sı (%68.5) kadın ve 113’ü (%31.5) erkekti. Katılım oranı %61.81 idi. Yaş ortalaması 19.4±1.1 olan katılımcıların %12.3’ü kronik ilaç kullanmaktaydı. En çok satın alınan ilaçlar ağrı kesicilerdi. AİK ölçeği başarı ortalaması 36.6±4.2 oldu. Tıp fakültesi öğrencilerinin AİK bilgi ve davranışları diş hekimliği ve eczacılık fakültesi öğrencilerine kıyasla anlamlı şekilde daha yüksekti (p=0.002). Ölçeğe göre kadın öğrenciler erkeklerden daha başarılıydı (p=0.001). Sürekli ilaç kullanmak, SKT’ye dikkat etmek, prospektüs okuma alışkanlığı ve komşu/yakın tavsiyesi ile ilaç kullanmama AİK ölçeğinde başarılı olanları başarısız olanlardan ayıran davranışlardı (p=0.002), (p<0.001), (p=0.001), (p<0.001). Sonuç: Tıp Fakültesi öğrencileri eğitimlerinin ilk yılında diş hekimliği ve eczacılık fakülteleri öğrencilerine göre AİK’de daha başarılıydı. Her üç fakülte öğrencisinin AİK puanları ise toplum ortalamasının üstündeydi. Başarılı olan ve olmayan bireyler arasında ortak davranışlar söz konusuydu. Sonuç olarak, ilaç reçete edecek ve karşılayacak sağlıkçılar olarak tıp, diş hekimliği ve eczacılık fakültelerinin uzun lisans eğitimlerinde AİK farkındalığı artırılmalı ve AİK davranışları asgari düzeyde eşitlenmeye çalışılmalıdır.Öğe Impact of Drugs Effective for Neuropathic Pain on the Frequency of Hospitalization, Debridement and Amputation Need in Patients with Diabetic Foot Infection(Doc Design Informatics Co Ltd, 2024) Tanir, Busra; Ugur, Kader; Kurt, Osman; Balin, Safak OzerObjective: This study aimed to investigate the impact of drugs used in the treatment of diabetic neuropathy on the frequency of hospitalization, need for debridement and amputation. Methods: One hundred forty-four patients who received inpatient treatment for diabetic foot infection between 2017 and 2020 were analyzed retrospectively through patient files. Patients without diabetic neuropathy were defined as Group 0, those with diabetic neuropathy who used drugs for diabetic neuropathy as Group 1, and those who did not use drugs for diabetic neuropathy were defined as Group 2. The groups were compared in terms of age, height, weight, gender, comorbidities, time elapsed after diabetes mellitus diagnosis and diabetic neuropathy, quantity of diabetic foot attacks, hospitalizations due to diabetic foot infection, need and quantity of debridement and amputation. Results: The time since diagnosis of diabetes mellitus, the rate of insulin use, and hospitalizations due to diabetic foot infection were higher in patients with diabetic neuropathy compared with patients without neuropathy (p=0.01, p=0.02, p=0.024). The difference between Groups 1 and 2 in terms of diabetic foot infection attacks, hospitalizations and debridement needs was statistically significant (p=0.039, p=0.02, p=0.06). When comparing whether or not debridement or amputation was required due to diabetic foot infection and the number of amputations, there was no statistically significant difference between the groups. Conclusions: The results of our study suggest that although the use of medications effective for neuropathic pain does not significantly affect amputation due to diabetic foot, it has a protective effect on the number of diabetic foot attacks, the number of hospitalizations due to diabetic foot, and the number of debridement needs.Öğe Impact of earthquakes on adolescent future expectations: Insights from a study in Türkiye(2025) Kurt, Osman; Konyalıoğlu, Fatma Sena; Kılıç, Fedli Emre; Öz, Erdoğan; Küçükkelepçe, OsmanObjectives: While earthquakes impact the future expectations of entire societies, adolescents bear a hefty burden due to their transitional stage of life and the intricacies of adolescence itself. Our study examined the factors influencing the future expectations of adolescents residing in the region six months after the earthquake. Methods: A face-to-face survey was conducted involving 385 individuals aged 11 to 17 affected by the February 6 earthquake in Turkey. The survey included sociodemographic inquiries, questions regarding earthquake experiences, and the administration of the Future Expectation scale to all participants. Results: Participants who lost their family members, who were trapped under the debris, and whose family members were trapped under the debris had significantly lower future expectations. Moreover, happier individuals, who perceived themselves as healthier and more socialized, had significantly higher future expectations. Female individuals had significantly lower future expectations in all subdimensions of the scale. Lastly, adolescents who changed their career aspirations post-earthquake exhibited higher scores in all subdimensions of the scale compared to those who did not undergo such changes. Conclusions: Adolescents confronted with traumatic events like earthquakes, particularly those who have lost relatives, often experience a negative impact on their future expectations. However, during subsequent phases, adolescents who report happiness, improved health, and increased socialization tend to harbor more positive outlooks for the future. This underscores the significance of implementing psychosocial rehabilitation efforts following earthquakes.Öğe Inflammation markers in patients with psychotic disorder who have committed offenses and their relationship with criminal behavior(Routledge Journals, Taylor & Francis Ltd, 2025) Yildiz, Sevler; Emir, Burcu Sirlier; Kilicaslan, Asli Kazgan; Kurt, Osman; Ugur, Kerim; Sehlikoglu, Seyma; Atmaca, MuradThe role of inflammation in the etiology of psychotic disorders (PD) is well-established. This study aimed to identify inflammation parameters in patients diagnosed with PD, assess their potential as biomarkers, and examine their relationship with criminal behavior. This retrospective study comprised three groups: 530 patients diagnosed with PD who had committed crimes (offenders with PD), 530 patients with PD who had not committed crimes (non-offenders with PD), and 530 healthy controls, totaling 1,590 participants. Routine hematological tests were used to measure neutrophil, lymphocyte, monocyte, and platelet counts, high-density lipoprotein (HDL), systemic inflammatory response index (SIRI), systemic immune-inflammatory index (SII), and neutrophil/HDL (NHR), lymphocyte/HDL, platelet/HDL (PHR), and monocyte/HDL (MHR) ratios. Offenders with PD exhibited significantly higher levels of SII, SIRI, PHR, NHR, LHR, neutrophils, and monocytes compared to non-offenders with PD and healthy controls (p < 0.001). The criminal group had lower HDL and lymphocyte levels than the remaining two groups (p < 0.001). Among those treated in forensic psychiatry units, patients with two or more treatments showed significantly higher SIRI values compared to those with only one treatment (p = 0.045). Non-offenders with PD had higher platelet values than the remaining two groups (p < 0.001). This study underscores the role of systemic inflammation in the pathophysiology of psychotic disorders through a comparison of patients who have and have not committed crimes, highlighting the relationship between inflammation and lipid metabolism. Further research is required to clarify these findings.Öğe Inflammatory markers and delirium in the intensive care unit(Mre Press, 2025) Yildiz, Sevler; Uslu, Muhammed Fuad; Emir, Burcu Sirlier; Kurt, OsmanBackground: Delirium is an important complication in patients admitted to intensive care unit (ICU). However, delirium prediction in patients admitted to the ICU is difficult. Considering the role of neuroinflammation in delirium, peripheral blood-based biomarkers of inflammation pressure could predict delirium. The aim of study was to retrospectively analyze ratios of neutrophil/high density lipoprotein (HDL) (NHR), lymphocyte/HDL (LHR), platelet/HDL (PHR), monocyte/HDL (MHR), as well as systemic immune-inflammation index (SII) and systemic inflammatory response index (SIRI) in ICU patients diagnosed with delirium. Methods: The study included a total of 2141 patients with or without delirium. The risk factors for delirium development and the predictive power of individual laboratory parameters were evaluated with the Pearson chi-square test, Mann-Whitney U test, Spearman correlation test, logistic regression, and receiver operating characteristic analyses. Results: Length of ICU stay (p < 0.001), NHR (p = 0.035), LHR (p < 0.001), PHR (p = 0.047), MHR (p < 0.001), SIRI (p < 0.001), and SII (p < 0.001) were significantly higher in patients who developed delirium compared to those who did not. A significant negative correlation was found between the duration of delirium and SII (r = -0.260; p = 0.004). Older age, a history of psychiatric treatment, prolonged hospitalization, and high LHR, SIRI, and SII values were determined as risk factors for delirium (p < 0.05 for all). Conclusions: Elevated LHR, SIRI, and SII levels before ICU admission are associated with an increased risk of hyperactive delirium. If confirmed by prospective evidence, readily available biomarkers for inflammation could be used to evaluate the hyperactive delirium risk in ICUs.Öğe Investigation of social support perceptions and mental health of postpartum women following the February 6, 2023 Turkey earthquake: a comparative study(Springer, 2025) Sehlikoglu, Seyma; Bekircan, Esra; Cicek, Sevil; Kurt, Osman; Yildiz, Sevler; Simsek, Yavuz; Emir, Burcu SirlierNatural disasters, such as earthquakes, have significant psychological consequences, particularly for vulnerable populations like postpartum women. This study aimed to determine the relationship between perceived social support and mental health among postpartum women who had experienced an earthquake. In this comparative cross-sectional study, the case group (n = 62) consisted of women who were in their third trimester at the time of the earthquake and gave birth after the disaster, while the control group (n = 62) comprised women who were also in their third trimester during the earthquake and had given birth but were not residing in the earthquake-affected region and had no prior experience of an earthquake. The study did not include individuals with intellectual disabilities, illiteracy. Data were collected using the Sociodemographic data form, the Edinburgh Postnatal Depression Scale, the Multidimensional Scale of Perceived Social Support (MSPSS), the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), and the Post-Traumatic Growth Inventory (PTGI). The incidence rates of Posttraumatic Stress Disorder (40.3%) and Edinburgh Postnatal Depression Scale (43.5%) in postpartum women who experienced the earthquake were significantly higher than those in women who did not (Posttraumatic stress disorder: 6.5%, Edinburgh Postnatal Depression Scale: 16.1%) (p <.001). The mean total MSPSS score of postpartum women who experienced the earthquake (61.7 +/- 16.9) was significantly higher than that of those who did not (51.9 +/- 13.2) (p <.001). The mean PTGI total score in postpartum women who experienced the earthquake (69.0 +/- 19.2) was significantly higher than in the control group (57.3 +/- 20.0) (p <.001). In postpartum women who experienced the earthquake, there was a significant positive correlation between PTGI and MSPSS scores, and between PCL-5 and Edinburgh Postnatal Depression Scale scores (p <.001). Pregnant women who experienced the earthquake had significantly higher posttraumatic stress disorder and postpartum depression scores compared to those who did not. It was concluded that perceived social support may promote posttraumatic growth in women who have experienced a postpartum earthquake.Öğe Investigation of social support perceptions and mental health of postpartum women following the February 6, 2023 Turkey earthquake: a comparative study (Vol 44, pg 13887, 2025)(Springer, 2025) Sehlikoglu, Seyma; Bekircan, Esra; Cicek, Sevil; Kurt, Osman; Yildiz, Sevler; Simsek, Yavuz; Emir, Burcu Sirlier[No abstract available]Öğe Markers of inflammation in patients with generalized anxiety disorder(Cukurova Univ, Fac Medicine, 2024) Yildiz, Sevler; Kilicaslan, Asli Kazgan; Emir, Burcu Sirlier; Tabara, Muhammed Fatih; Kurt, Osman; Sehlikoglu, Seyma; Ugur, KerimPurpose: The aim of this study was to analyze the systemic immune response index, systemic immune inflammation platelet/HDL, and monocyte/HDL ratio, used as inflammatory markers in patients with generalized anxiety Materials and Methods: A total of 864 participants, including 432 healthy controls and 432 patients diagnosed with GAD, were included in this study. High-density lymphocyte, and platelet counts; systemic inflammatory calculated. contributing to both diagnosis and management.
