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Öğe The evaluation of our newborns cases operated due to necrotizing enterocolitis(2017) Korkmaz, Levent; Bastug, Osman; Daar, Ghaniya; Korkut, Sabriye; Halis, Hulya; Ozdemir, Ahmet; Ceylan, Mahir; Gunes, Tamer; Ozturk, Mehmet Adnan; Kurtoglu, SelimAim: This study aimed to investigate the characteristics of newborns operated due to necrotizing enterecolitis (NEC) in newborn intensive care unit and to evaluate the mortality of these patients. Material and Methods: The research was designed retrospectively. The study included 39 patients operated due to NEC in our newborn intensive care unit between January 2010 and December 2015 and their characteristic factors and prognosis were evaluated. Results: The average gestational age and weight at birth of the newborns were 31.5±3.7 weeks, 1861±817 g respectively. There were significant differences between the newborns who died and survived in respect to birth weight, age at the time of operation, presence of antenatal steroid application, hypoxic ischemic encephalopathy, intestinal presence of perforation, blood culture positivity (p<0.05 for all comparisons). Conclusion: NEC is the most common life-threatening gastrointestinal emergency experienced by premature infants cared for in the newborn intensive care unit. It is thought that the most important ethiologic factors are prematurity, hypoxia and enteral nutrition. At the same time, it is a devastating gastrointestinal disease that is associated with severe sepsis, intestinal perforation, and significant morbidity and mortality. Its mortality and morbidity rates have been reduced due to developments in newborn intensive care. However, mortality rate is still high among newborns operated due to NEC. For these reasons our thought is that promptly arranged operation time can help to reduce the frequency of mortalityÖğe Maternal hypoparathyroidism related transient normocalcemic hyperparathyroidism in newborns: case report(2017) Kurtoglu, Selim; Ozdemir, Ahmet; Korkmaz, LeventMaternal hypoparathyroidism causes enlargement in fetal parathyroid glands and hyperparathyroidism. This kind of neonatal hyperparathyroidism may lead tohypercalcemia. Normocalcemia may be observed in some cases. This temporary presentation of hyperparathyroidism generally recovers in a few days after birth as the infant takes enough amount of calcium and phosphorus. Especially significant intrauterine growth retardation and mortality rates are high in infants born from mothers with poorly controlled or untreated hypoparathyroidism. Contrary to the severe hyperparathyroidism of the newborn, these infants often have low birth weight, suppressed or normal serum calcium levels and normal or a little high serum phosphorus levels. The reasons for this difference between the two groups are unknown. In this article, literature was examined by presenting the case of an infant who had transient normocalcemic hyperparathyroidism and the mother who had thyrodectomy and hypoparathyroid symptoms and inadequate treatment during pregnancy.Öğe A study of longitudinal measurements in the screening for osteopenia of prematurity(2018) Korkut, Sabriye; Kurtoglu, SelimAim: To investigate the biochemical parameters and bone “speed of sound” (SoS) values used in the screening for osteopenia of prematurity (OP). Material and Methods: Serial measurements of tibial bone SoS and concomitant serum calcium (Ca), phosphorus (P), and alkaline phosphatase (ALP) levels of preterm infants in postnatal week 1, 3, and 6 were studied retrospectively. Results: Fifty premature infants ≤ 35 weeks of gestational age were included in the study. A positive correlation was detected between serum P levels and SoS values at 1st and 6th week (r = 0.55, P = 0.0001 and Rho = 0.67, P = 0.0001, respectively). SoS values in postnatal week 3 were correlated with SoS values in week 1 and week 6 (Rho = 0.67, P = 0.0001 and Rho = 0.65, P = 0.0001, respectively). Serum Ca, P, and ALP levels measured in postnatal week 1 and 3 were not predictive of the subsequent risk of osteopenia. The SoS value in week 3 (≤ 2940 m/s) was predictive of the risk of osteopenia in week 6, with sensitivity of 85% and specify of 73% (Area under the curve [AUC] = 0.80, p = 0.001). Conclusions: Serum P levels were correlated with bone SoS values. Bone SoS measurements in postnatal week 3 rather than biochemical parameters was predictive of the risk of osteopenia in postnatal week 6. For this reason, screening for osteopenia can be started at postnatal week 3 in newborn units where quantitative ultrasonography (QUS) is used.