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Öğe Adrenoleukodystrophy: single voxel MR spectroscopy findings (case report)(2004) Alkan A.; Kutlu R.; Aslan M.; Yakinci C.Adrenoleukodystrophy is a rare genetic disorder. Histopathological features of this disorder include demyelination and axonal loss in white matter. We describe a six-year-old boy with significantly decreased N-acetyl-aspartate (NAA)/Creatin (Cr), increased Choline (Cho)/Cr and Myo-inositol (MI)/Cr in parieto-occipital white matter by MR spectroscopy. In contrast to the normal appearance of frontal white matter on MR imaging, increased Cho/Cr and MI/Cr ratios were detected on MR spectroscopy. These changes in involved areas could be an indication of neuroaxonal loss, demyelination and gliosis.Öğe Associated brain anomalies and clinical findings in corpus callosum dysgenesis(2003) Alkan A.; Kutlu R.; Baysal T.; Sigirci A.; Altinok T.; Orkan I.; Hallaç T.PURPOSE: The aim of this study was to evaluate the relationship between the types of the corpus callosum dysgenesis, the associated brain anomalies and clinical findings. MATERIALS AND METHODS: We analyzed the MR imaging findings in 169 patients with callosal dysgenesis. Corpus callosum dysgenesis was categorized into agenesis, hypogenesis and hypoplasia. The associated brain anomalies and clinical findings were evaluated. RESULTS: Associated brain anomalies were observed in 148 patients (87.5%). Twenty-one patients (12.4%) had isolated corpus callosum dysgenesis. Dysgenesis included agenesis in 22 (%13), hypogenesis in 46 (27.2%), and hypoplasia in 101 (59.7%) patients. The clinical findings were most commonly observed in patients with hypoplasia. CONCLUSION: The presence of corpus callosum dysgenesis is a strong indication of possible associated brain anomalies. Corpus callosum dysgenesis and associated brain anomalies should be investigated in children with developmental delay, seizures and microcephaly.Öğe Atlanto-axial subluxation associated with Rubinstein-Taybi syndrome(Elsevier BV, 2003) Si?irci A.; Yakinci C.; Alkan A.; Aslan M.; Si?irci A.; Kutlu R.A case of atlanto-axial subluxation in a 5-year-old boy with Rubinstein-Taybi syndrome (RTS) is presented and the imaging findings are evaluated. To the best of our knowledge, atlanto-axial subluxation has not been reported in association with this syndrome. © 2003 Elsevier Ireland Ltd. All rights reserved.Öğe Celiac ganglion blockade: the effectiveness of CT guided percutaneous anterior approach(2003) Alkan A.; Durak A.C.; Ozcan N.; Kutlu R.; Baysal T.; Sigirci A.PURPOSE: To investigate the effectiveness and safety of celiac ganglion blockade in cases with abdominal malignancies who are narcotic analgesic dependent for control of severe abdominal pain. MATERIALS AND METHODS: A total of 30 celiac ganglion blockades were performed in 27 patients between the ages of 19 and 75. A 22 G Chiba needle was placed through the percutaneous anterior approach into the celiac ganglion region under the guidance of CT, and 98% alcohol was administered. The procedure was repeated in three cases due to insufficient response. RESULTS: In 24 (88.8%) of the 27 cases, the severity of pain decreased. Total relief of the pain was achieved in 13 (48.1%) cases. In 9 (33.3%) cases pain was controlled with non-narcotic analgesics. In 2 (7.4%) cases, the dose of the narcotic analgesic decreased. There was no change in the severity of the pain in 3 (11.1%) cases. Transient complications were diarrhea in 4 (14.8%), hypotension in 6 (22.2%) cases and hemiparesis in one (3.7%) case. CONCLUSION: Celiac ganglion blockade through the percutaneous anterior approach under the guidance of CT should be preferred for the control of pain in the early periods in cases with abdominal malignancies, especially gastric and pancreatic, due to easy performance, safety, lower incidence of complications, high success rate and low cost.Öğe Diffusion-weighted magnetic resonance imaging and magnetic resonance spectroscopy features of abdominal viscera in a patient with Gaucher's disease(Malaysian Journal of Medical Sciences, 2014) Kalayci T.O.; Erdem G.; Kutlu R.; Kahraman A.; Alkan A.A 46-year-old woman with Gaucher's disease (GD) consulted our clinic for abdominopelvic magnetic resonance imaging (MRI), as physical examination had revealed hepatosplenomegaly. Upper abdominal MRI showed massive hepatosplenomegaly and innumerable hypointense splenic nodules on T1-weighted images. Diffusion-weighted MRI (DW-MRI) and magnetic resonance spectroscopy (MRS) were performed to liver parenchyma and splenic nodules. MRS revealed lactate, lipid, acetate, and alanine peaks in splenic nodules, and choline, creatine, lipid, myo-inositol-glycine, and lactate peaks in the liver parenchyma. The DW-MRI showed diffusion restriction in splenic nodules. It was concluded that MRI is a reliable method for the diagnosis and follow up of GD. Coupling DW-MRI and MRS allows quantitative evaluation, thereby increasing the efficacy of the method. This is the first report in the literature presenting advanced abdominal MRI findings in GD. © Penerbit Universiti Sains Malaysia, 2014.Öğe Doppler waveforms and blood flow parameters of the superior and inferior mesenteric arteries in patients having Behçet disease with and without gastrointestinal symptoms: Preliminary data(John Wiley and Sons Ltd, 2003) Si?irci A.; Şenol M.; Aydin E.; Kutlu R.; Alkan A.; Altinok M.T.; Yolo?lu S.Objective. To evaluate hemodynamic changes in mesenteric arteries in patients with Behçet disease with and without gastrointestinal symptoms. Methods. Doppler sonography of mesenteric arteries was performed in 25 symptomatic and 15 asymptomatic patients having Behçet disease and in 25 healthy control subjects. The peak systolic, minimal, and mean velocities, resistive and pulsatility indexes, inner diameter, cross-sectional area, and blood flow volume of mesenteric arteries were evaluated. The results were compared between patient groups and controls. Results. The mesenteric artery flow was significantly greater in patients in the symptomatic group than in those in the asymptomatic group or in controls. In the superior mesenteric artery, mean velocity and mean blood flow volume (0.35 ± 0.18 m/s and 711 ± 404 mL/min, respectively; P < .0001) in the symptomatic group were significant]y higher than in the asymptomatic group (0.16 ± 0.07 m/s and 305 ± 168 mL/min, respectively) or in controls (0.15 ± 0.07 m/s and 290 ± 123 mL/min, respectively). The mean peak systolic velocity (1.23 ± 0.47 m/s; P < .005) in the symptomatic group was significantly higher than in controls (0.93 ± 0.23 m/s). In the inferior mesenteric artery, mean velocity and mean blood flow volume (0.25 ± 0.10 m/s and 139 ± 79 mL/min) in the symptomatic group were significantly higher than in the asymptomatic group (0.16 ± 0.07 m/s; P < .006; and 78 ± 26 mL/min; P < .007) or in controls (0.17 ± 0.07 m/s; P < .003; 83 ± 48 mL/min; P < .004). Conclusions. In this study, symptomatic patients with gastrointestinal Behçet disease were associated with a significant increase in mesenteric artery flow that could be evaluated easily on spectral patterns of arteries during Doppler sonography. The Doppler sonographic findings also revealed that intestinal involvement in patients with Behçet disease without gastrointestinal symptoms is not significantly different from that of healthy controls.Öğe Dural cavernous hemangioma originating from superior petrosal sinus(2002) Koçaki A.; Çayli S.R.; Önal S.Ç.; Kutlu R.; Aydin N.E.Cavernous angiomas of the dura are rare and have been described in the literature particularly in the middle cranial fossa. We present a case of cavernous hemangioma of the middle cranial fossa arising from the superior petrosal sinus. In our review of the literature, this is the 2nd report describing a cavernous hemangioma in such a location.Öğe Effects of testicular microlithiasis on Doppler parameters: Report ofthreecases(BioMed Central Ltd., 2002) Kutlu R.; Sigirci A.; Baysal T.; Alkan A.; Sarac K.Background: Testicular microlithiasis is a rare, usually asymptomatic, non-progressive disease of the testes associated with various genetic anomalies, infertility and testicular tumors. According to our literature search, there is no specific data about Doppler findings in this disease. Case presentation: Doppler findings of three cases of testicular microlithiasis during last two years in our institution are presented. Conclusions: Although our hypothesis was to find increased Doppler parameters due to intratesticular arterial compression, our findings suggest that there are no Doppler findings specific to testicular microlithiasis.Öğe An en-plaque tentorial lesion in a pregnant woman: Follow-up with MRI (2003:2a)(2003) Alkan A.; Parlak M.; Baysal T.; Sigirci A.; Kutlu R.; Altinok T.[No abstract available]Öğe En-plaque tuberculomas of tentorium in a pregnant woman: Follow-up with MRI (2003:2b)(Springer Verlag, 2003) Alkan A.; Parlak M.; Baysal T.; Sigirci A.; Kutlu R.; Altinok T.En-plaque tuberculoma is a rare manifestation of CNS tuberculosis and presents as a solitary, focal, caseous plaque-like lesion. It is difficult to differentiate en-plaque like meningeal tuberculoma from true primary or secondary meningeal neoplasia. Good response to antituberculosis treatment in a patient with tuberculosis history and typical MR findings confirm the diagnosis. We present the follow-up MR imaging findings of a case in which an en-plaque tuberculoma on tentorium was diagnosed during pregnancy in a patient with a history of tuberculosis. To the best of our knowledge, en-plaque tuberculomas of tentorium during pregnancy have not been reported before.Öğe An end-plate chondroma mimicking calcified lumbar disc herniation: A case report and review of the literature(1999) Erten S.F.; Koçak A.; Mizrak B.; Kutlu R.; Çolak A.The authors report a case of chondroma arising from a vertebral end- plate and mimicking lumbar disc herniation. This tumor became calcified within 2 weeks. It was completely removed surgically, after which the patient's symptoms were relieved and neurological deficits regressed.Öğe Endovascular treatment of huge saccular abdominal aortic aneurysm in a young Behcet patient: Mid-term result(2002) Kutlu R.; Gulcan O.; Akbulut A.; Turkoz R.; Baysal T.Background: Abdominal aortic aneurysm formation is among the arterial complications of Behcet's disease. Weakness and fragility of aortic walls leads to the development of arterial complications like pseudoaneurysms. Case Presentation: A case of huge saccular abdominal aortic aneurysm in a young Behcet patient who was successfully treated with endovascular stent graft placement is reported, diagnostic and interventional procedures are discussed, and mid-term follow-up results are presented. Conclusions: Endovascular treatment of abdominal aortic aneurysm complications of young Behcet patients who are not suitable for open surgery and need intervention could be an alternative treatment modality even without performing preprocedural angiography. © 2002 Kutlu et al; licensee BioMed Central Ltd.Öğe Gastric perforation during chest tube placement for acute diaphragmatic rupture and review of the literature(Elsevier BV, 2006) Yilmaz M.; Isik B.; Ara C.; Yilmaz S.; Kutlu R.; Kocak O.; Ugras M.[No abstract available]Öğe Individual patient assessment and therapy decision-making in a live donor-based liver transplant institute(Springer International Publishing, 2021) Carr B.I.; Yilmaz S.; Isik B.; Kutlu R.Patients with HCC present with both their tumor and underlying liver disease, requiring input from several disciplines for optimal therapeutic decision-making. We describe our method, which emphasizes the importance of a multidisciplinary approach and a tumor board. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2021. All rights reserved.Öğe MR spectroscopy in the differential diagnosis of focal brain lesions in neurofibromatosis type 1 patients(2003) Alkan A.; Kutlu R.; Sigirci A.; Baysal T.; Altinok T.; Dusak A.; Saraç K.PURPOSE: To determine the role of MR spectroscopy in the differential diagnosis of focal brain lesions in neurofibromatosis type 1. MATERIALS AND METHODS: Fifteen patients with neurofibromatosis type 1 were evaluated by routine MRI and single voxel MR spectroscopy (TE: 31). The posterior parietal white matter of 20 age-matched healthy volunteers constituted the control group. NAA/Cr, Cho/Cr and MI/Cr ratios were calculated and compared with the control group. RESULTS: A total of 58 focal brain lesions were detected by MR imaging. When patients with hamartomas and gliomas were compared with the control group, a decrease in the NAA/Cr ratio, and a significant increase in Cho/Cr and MI/Cr ratios were found. The decrease in the NAA/Cr ratio and the increase in Cho/Cr and MI/Cr ratios of gliomas were significant when compared with hamartomas. With MRI and MR spectroscopy findings, 52 hamartomas and 6 gliomas were detected. CONCLUSION: Since MR spectroscopy has the ability to detect cellular metabolic changes, it could provide additional information to MR imaging about the differential diagnosis and treatment planning of focal parenchymal lesions in neurofibromatosis type 1.Öğe Postintubation tracheal rupture(2001) Kutlu R.; Kuzucu A.; Soysal Ö.; Baysal T.; Karaman I.; Akbulut A.Tracheal rupture following endotracheal intubation is an extremely rare emergency that needs expedient diagnosis and treatment. The clinical and radiological features of postintubation tracheal rupture in a 45-year-old woman who underwent vertebral stabilization are described. Primary suture closure was performed successfully via a cervical approach. © 2001 SAGE Publications.Öğe Pseudoaneurysm of the internal jugular vein after mumps: Ultrasonographic evaluation(Elsevier BV, 2003) Si?irci A.; Kuranel S.; Kutlu R.; Alkan A.; Altinok T.We report a case of pseudoaneurysm following mumps infection in the left internal jugular vein with sonography and Doppler ultrasound findings. The diagnosis was confirmed during surgical exploration. To the best of our knowledge, this is the first case report of an internal jugular vein false aneurysm in the literature. © 2002 Elsevier Science Ireland Ltd. All rights reserved.Öğe Pulmonary embolism after penile deep dorsal vein embolization with n-butyl-2-cyanoacrylate and lipiodol mixture(Elsevier BV, 2004) Kutlu R.; Soylu A.; Alkan A.; Turker G.Venogenic erectile dysfunction is an important problem. Embolization of draining veins through penile deep dorsal vein is an effective alternative endovascular treatment procedure. We report a 27-year-old male with venogenic erectile dysfunction who developed pulmonary embolism after penile deep dorsal vein embolization with n-butyl-2-cyanoacrylate (NBCA) and lipiodol mixture. Although it is uncommon, due to inherent possible complications of liquid embolic material n-butyl-2-cyanoacrylate and lipid soluble contrast material lipiodol, symptomatic pulmonary embolism could be seen after deep dorsal vein embolization if the amount of lipiodol is increased and repeat injection is performed without performing a control venogram. © 2003 Elsevier Ireland Ltd. All rights reserved.Öğe Radiological case of the month(2004) Kutlu R.; Kocak A.; Cayli S.; Alkan A.; Sigirci A.; Sarac K.[No abstract available]Öğe Reversible posterior leukoencephalophaty in a child with acute glomerulonephritis: Follow-up MR imaging(2003) Alkan A.; Kutlu R.; Baysal T.; Si?irci A.; Sönmezgöz E.; Yakinci C.Hypertensive encephalopathy is the most common cause of reversible posterior leukoencephalopathy syndrome, which is quite rare in the pediatric age group. Diffuse vasogenic edema in the posterior circulation territories at the initial stages and complete disappearance of edema on follow-up imaging is the characteristic feature of this syndrome. Frontal and temporal lobe involvement is rarely seen. In this report we present the follow-up MR and diffusion weighted imaging findings of reversible posterior leukoencephalopathy syndrome in a pediatric case with this rare involvement in addition to characteristic involvement localization.
