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    Evaluation of sleep quality and nutritional status of patients with frequent ventricular premature complexes
    (2020) Kuyumcu, Aliye; Kuyumcu, Mevlut Serdar
    Aim: Rhythm disturbances in the heart significantly affect the quality of life of the patients. The aim of this study was to investigate the effect of ventricular premature complexes (VPC) on sleep quality and nutritional status.Material and Methods: This study was conducted on 50 patients with palpitations who were referred to the cardiology outpatient clinic and had more than 10,000 VPC per day as a result of a 24-hour holter, and 50 patients who presented with palpitations but had less than 10,000 VPC in the holter. Demographic characteristics, nutritional status, sleep quality and some anthropometric measurements of the patients were evaluated using a questionnaire. Food consumption record was taken to determine daily energy and macro nutrient intake of individuals. Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality.Results: PSQI scores indicating decreased sleep quality were found to be high in the VPC group (p0.001). Energy consumption (p = 0.004) and carbohydrate consumption (p0.001) were significantly higher in the VPC group. Saturated fatty acid consumption was high (p0.001) and polyunsaturated fatty acid consumption was low in the VPC group (p0.001).There was significant positive correlation found between VPC count and PSQI scores (p0.001, r = 0.788).Conclusion: It was clearly observed that the frequency of VPC decreases sleep quality and leads to imbalances in individuals’ nutritional status. Therefore, in addition to the medical treatment of rhythm disorder, individuals should be given training to improve sleep quality and nutritional status by a multidisciplinary team (such as doctors, dietitians, psychologists).
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    High fructose consumption may have part in the pathophysiology of coronary artery ectasia
    (2020) Kuyumcu, Aliye; Kuyumcu, Mevlut Serdar
    Aim: A coronary artery may partly become a half or one diameter larger than an adjoining normal one as observed on angiograms, which is called coronary artery ectasia (CAE). There is strong evidence that oxidative stress and inflammation may contribute to the CAE pathophysiology, potentially due to higher fructose intake. Our study aims to determine the effects of the amount of fructose consumed on isolated CAE. Material and Methods: The study group consists of the patients with stable angina pectoris who had coronary angiography (CAG) reports dated from December 2018 to April 2019. Based on these reports, sampling was made as follow: the patient or CAE group of 50 patients also with isolated CAE and the control group of 50 patients with normal coronary flow pattern (NCF). A comparative analysis was performed using the exact data of both groups including nutrient consumption.Results: The patient group with higher high-sensitivity C-reactive protein levels (p = 0.029), greater platelet count (p = 0.015), and increased hypertension rate (p = 0.012) were observed to have higher energy in total (p = 0.008), carbohydrate (p = 0.003), and fructose intake (p0.001). Multivariable logistic regression analyses demonstrated that rising Hs-CRP levels (p = 0.031), greater platelet count (p = 0.017), higher fructose intake (p = 0.029), and increased hypertension (p = 0.032) were individually associated with CAE.Conclusion: In the CAE group higher fructose consumption was observed and thus determined to potentially contribute to the CAE pathophysiology.
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    Mediterranean diet effects on ventricular premature complexes
    (2020) Kuyumcu, Aliye; Kuyumcu, Mevlut Serdar
    Aim: The aim of this study was to evaluate the relationship between ventricular premature complexes (VPC) and Mediterranean diet score. Rhythm disturbances in the heart significantly affect the quality of life of the patients. Material and Methods: This study was conducted on 50 patients with palpitations who were referred to the cardiology outpatient clinic and had more than 10000 VPC per day as a result of a 24-hour holter, and 50 patients who presented with palpitations but had less than 10,000 VPC in the holter. Diet quality was determined by scoring method (5, 6-9 and ≥10 points) ‘Mediterranean Diet Adaptation Scale’ and compared between groups.Results: There was no difference between the two groups in terms of clinical and demographic characteristics. Mediterranean diet scores were found lower in patients with VPC’s ≥10.000/day (p0.001). There was a significant negative correlation found between number of VPC and Mediterranean diet score (p0.001, r = -0.652).Conclusion: The protective role of Mediterranean diet type nutrition on the frequency of VPC was clearly observed in our study. This study, which is one of the limited numbers of studies examining the relationship between Mediterranean diet and VPC, may be helpful in understanding the pathophysiology of VPC.
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    Monocyte count to high-density lipoprotein cholesterol ratio may be a predictor in ascending aortic aneurysm
    (2020) Kuyumcu, Mevlut Serdar; Ozen, Yasin; Ozbay, Mustafa Bilal; Kuyumcu, Aliye
    Aim: The predictive value of the monocytes count and HDL-cholesterol ratio (MHR) has been demonstrated in several cardiovascular diseases. Ascending aortic aneurysm (AAA) is an important cause of mortality in adults. The aim of our study was to investigate the relationship between MHR and AAA in patients with hypertension. Material and Methods: 240 consecutive patients with AAA and 240 consecutive patients with normal ascending aortic diameter were recruited into the study by comprehensive transthoracic echocardiography. All data and MHR was compered between two groups.Results: MHR levels were significantly higher in AAA group compared to normal ascending aortic diameter group (p0.001). Higher levels of MHR was found significantly and independently associated with the AAA (p0.001). Also there was significant positive correlation between the diameter of the ascending aorta and the MHR (p0.017).Conclusion: MHR as a marker of chronic low-grade inflammation may play a role in the pathogenesis of aneurysm of the ascending aorta.