Yazar "Malkoc, S." seçeneğine göre listele

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    Biocompatibility evaluation of orthodontic composite by real-time cell analysis
    (Sage Publications Ltd, 2016) Ersoz, M.; Malkoc, S.; Kucuk, E. B.; Bozkurt, B. S.; Hakki, S. S.
    Introduction: The aim of this study was to evaluate the cytotoxic effects of three different light-cured orthodontic composites. Material and methods: Light Bond (Reliance orthodontic products), Grengloo (Ormco corporation), and Kurasper F (Kuraray Europe GmbH) were selected for the experiment. Specimens were prepared according to the manufacturers' instructions, measuring 5 mm in diameter and 2 mm in thickness. Fibroblast cells were obtained from healthy gingival connective tissues. The composite cylinders were incubated in Dulbecco's modified Eagle's culture medium for 72 h according to ISO 10993-5 standards. The xCELLigence method was used to evaluate fibroblast cell vitality. After seeding 200 mL of the cell suspensions into the wells (20,000 cells/well) of the E-plate 96, gingival fibroblasts were treated with bioactive components released by the orthodontic composite materials and monitored every 15 min for 121 h. Results: There were no significant differences between the human gingival fibroblast (HGF) cell indexes of the control and all testing groups (p > 0.05) at 24 and 48 h. Light Bond demonstrated statistically significant decrease in HGF index (p < 0.05) at 72 h, but there was no significant difference among the Kurasper F, Grengloo, and untreated control groups (p > 0.05). Light Bond (p < 0.001) and Grengloo (p < 0.05) groups had lower HGF cell index values when compared to untreated control group, but Kurasper F demonstrated no significant differences between the control groups at 96 h (p > 0.05). Conclusion: Orthodontic composite materials include biologically active components and may change oral tissue. So, biocompatible orthodontic bonding composites should be used.
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    Comparison of Time-dependent Two-dimensional and Three-dimensional Stability with Micro-computerized Tomography and Wettability of Three Impression Materials
    (Wolters Kluwer Medknow Publications, 2018) Karaaslan, G.; Malkoc, M. A.; Yildirim, G.; Malkoc, S.
    Objectives: The objective of this study is to explore time-dependent dimensional stability of three different elastomeric impression materials -vinyl polyether silicone (VPES), vinyl polysiloxane (VPS), and polyether (PE) -through micro-computerized tomography (mu -CT) imaging, allows three-dimensional (3D) imaging and measurement without sample preparation or chemical fixation. Materials and Methods: Thirty specimens were created using 3 mm high, 30 mm wide Teflon molds (n = 10). Specimens were scanned with mu -CT on the 1st (T1) h and 1st (T2), 7th (T3), and 14th (T4) days. 3D models were created at the above-mentioned times, volumetric measurements were conducted and dimensional changes were calculated. Diameters and heights of each impression material were measured with 2D analyses. Furthermore, contact angle measurements of these elastomeric impression materials were collected using the sessile drop method during and after polymerization at 0, 2, 5, 20, 60, 120, and 240 s These measurements were made on specimens (n = 10) prepared in standard sizes using a 50 mu m deep stainless steel die with dimensions of 62 mm x 20 mm x 3 mm. Results: Evaluation of the dimensional volume changes of the VPES, VPS, and PE measurements showed there to be no statistically significant differences between the T1, T2, T3, and T4 (P > 0.05). Only the decreases in the volume averages of T3 and T4 in the VPES were statistically significant (P < 0.05). As a result of binary comparisons, the evaluation of contact angle measurements of VPES, VPS, and PE materials during and after polymerization were compared. The average contact angle measurements of the VPS group were statistically significantly lower than the averages of the VPES and PE groups (P < 0.01). Conclusions: VPS was found to be the most stable impression material concerning dimensional change and wettability.
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    An Evaluation of Effects Of Platelet-rich-fibrin on Postoperative Morbidities after Lower Third Molar Surgery
    (Wolters Kluwer Medknow Publications, 2017) Asutay, F.; Yolcu, U.; Gecor, O.; Acar, A. H.; Ozturk, S. A.; Malkoc, S.
    Objectives: The aim of the present study was to assess whether the use of platelet-rich fibrin (PRF) decreased the pain, swelling, and trismus levels of postoperative third molar surgery. Materials and Methods: In a double-blinded, split-mouth randomized study, thirty patients (6 male/24 female, mean age 20.32 years) with bilateral symmetric impacted third molars were enrolled in this study to receive surgery. The PRF mass was randomly placed in one of the extraction sockets, whereas the other socket was left without treatment. The outcome variables were pain, maximum mouth opening (trismus), swelling (edema), and the presence of dry socket which were measured using a 10-point visual analog scale, manual calipers, and 3dMD facial imaging system which was used for the 1st time in the third molar surgery. Results: Statistical analyses revealed that there were no significant differences between the control and study groups regarding postoperative pain, swelling, and trismus (P > 0.05). Conclusion: The results of this study suggest that PRF was not observed to have a positive effect on postoperative discomfort, so even though, PRF is presumed to have positive effects on healing and recovery processes.