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Öğe Assessment of Reliability of Three Different Computer-Assisted Analysis Programs(Aves Press Ltd, 2013) Toy, Ebubekir; Malkoc, Siddik; Altindis, Sedat; Aksakalli, SertacObjective: The aim of this study was to assess the reliability of cephalometric analysis using 3 different digital analysis programs. Methods: For this study, a dry human skull with the entire mandible, maxilla, and teeth was used. Fifteen lateral and 15 posteroanterior cephalometric digital images were taken by rotating the skull from 08 to 6148 at 28 intervals to obtain different images. Two researchers located the landmarks on the digital images independently using 3 computer-assisted analysis programs, Dolphin Image Software (Dolphin Imaging and Management Solutions), Quick Ceph Image (Quick Ceph Systems Inc), and Vistadent OC (GAC Int Inc). Following the first measurements (T1), all landmarks were relocated within a 2-week interval (T2) by each examiner. A paired and the independent Student t tests were used for intraexaminer and interexaminer measurements, and Pearson correlations were obtained. Intraclass correlation coefficients (ICC) were calculated to determine intraexaminer repeatability. Results: For the repeated measurements, mean differences were statistically insignificant, and high correlations for the repeated measurements were found, and the intraexaminer correlations were significant for each examiner (p <.001). When the interexaminer correlations of 3 analyses were compared, interexaminer correlations showed high consistency and the lowest Pearson r value was the same angular measurement (S ant-n-ss) (p <.001). ICC values demonstrated high intraexaminer repeatability. The highest value of ICC was the mandibular body length (go-me) for both examiners (p <.001). Conclusion: The 3 tested analysis programs may be accepted as reliable for clinical use.Öğe Bone regeneration by low-level laser therapy and low-intensity pulsed ultrasound therapy in the rabbit calvarium(Pergamon-Elsevier Science Ltd, 2016) Acar, Ahmet Huseyin; Yolcu, Umit; Altindis, Sedat; Gul, Mehmet; Alan, Hilal; Malkoc, SiddikObjective: We evaluated the efficacy of low-level laser therapy (LLLT) and low-intensity pulsed ultrasound (LIPUS), alone and in combination, in triggering new bone formation. Study design: Sixteen New Zealand white rabbits were given two calvarial defects by using a 6-mm trephine bur, then divided into four treatment groups: control, LLLT, LIPUS, and LLLT + LIPUS. The LLLT and LIPUS groups were treated three times a week for two weeks. The LLLT + LIPUS group received each treatment on the same day, 12 h apart, three days a week for two weeks. The animals were sacrificed after three weeks. Results: LLLT and LIPUS, alone and in combination, enhanced new bone formation in comparison to the untreated controls after three weeks (P < 0.05); the combined therapy did not produce an additive effect. Conclusions: Our results demonstrate the efficacy of LLLT or LIPUS in triggering bone regeneration. Therapeutic dose and duration requires further study. (C) 2015 Elsevier Ltd. All rights reserved.Öğe Comparison of the outcomes of the lower incisor extraction, premolar extraction and non-extraction treatments(Oxford Univ Press, 2012) Ileri, Zehra; Basciftci, Faruk Ayhan; Malkoc, Siddik; Ramoglu, Sabri IlhanThe aim of this retrospective study was to evaluate the treatment outcome of lower incisor extraction and to compare it with premolar extraction and non-extraction treatment. The sample consisted of 60 subjects with Class I malocclusion and moderate crowding. The sample was separated into three groups: extraction of a lower incisor group, extraction of a four first premolar group and a non-extraction group. All groups involved 13 girls and 7 boys with a total of 20 patients. The Peer assessment rating (PAR) index was applied to a patient's pre-treatment (T1) and post-treatment (T2) dental casts. T1 dental casts were also used for determining Bolton discrepancy. One-way analysis of variance and post hoc Tukey HSD tests were used for statistical analysis. For the mean percentage PAR score reduction for each group, there was one significant difference seen between the lower incisor extraction group and the non-extraction group (P = 0.047). For the mean anterior ratios, there were significant differences among premolar extraction group versus non-extraction group (P = 0.042) and non-extraction group versus lower incisor extraction group (P = 0.000). For the mean overall ratios, there were significant differences among the premolar extraction group versus lower incisor extraction group (P = 0.048) and the non-extraction group versus lower incisor extraction group (P = 0.001). Orthodontic treatment without extraction has a better treatment outcome than the four-first premolar extraction and single lower incisor extraction protocols in Class I cases with moderate to severe mandibular anterior crowding.Öğe Cytotoxic effects of orthodontic composites(E H Angle Education Research Foundation, Inc, 2010) Malkoc, Siddik; Corekci, Bayram; Ulker, Hayriye Esra; Yalcin, Muhammet; Sengun, AbdulkadirObjectives: To evaluate the cytotoxic effects of five different light-cured orthodontic bonding composites. Materials and Methods: The orthodontic composites Heliosit Orthodontic (Ivoclar), Transbond XT (3M Unitek), Bisco ORTHO (Bisco), Light Bond (Reliance), and Quick Cure (Reliance) were prepared, and the samples were extracted in 3 mL of BME (Basal Medium Eagle) with 10% newborn calf serum for 24 hours. The L929 cells were plated (25,000 cells/mL) in a 96-well dish and maintained in a humidified incubator for 24 hours at 37 degrees C, 5% CO(2), and 95% air. After 24 hours of incubation of the cells, the incubation medium was replaced by the immersed medium in which the samples were stored. Then, L929 cells were incubated in contact with eluates for 24 hours. The cell mitochondrial activity was evaluated by the methyl tetrazolium (MTT) test. Twelve wells were used for each specimen, and the MTT tests were applied two times. The data were statistically analyzed by one-way analysis of variance (ANOVA) and Tukey HSD tests. Results: Results with L929 fibroblasts demonstrated that except for Transbond XT, freshly prepared composite materials did not reduce vital cell numbers (P>.05) compared with the control group. Our data demonstrate that Transbond XT showed significant cytotoxicity compared with the control group. Conclusion: Results indicate that tested orthodontic bonding composites are suitable for clinical application, but that further studies using different test methods are needed for Transbond XT. (Angle Orthod. 2010;80:759-764.)Öğe Cytotoxic effects of resin-modified orthodontic band adhesives Are they safe?(E H Angle Education Research Foundation, Inc, 2010) Malkoc, Siddik; Corekci, Bayram; Botsali, Hayriye Esra; Yalcin, Muhammet; Sengun, AbduelkadirObjective: To evaluate the cytotoxic effects of three different resin-modified orthodontic band adhesives. Materials and Methods: Three resin-modified orthodontic band adhesives (Bisco Ortho Band Paste LC (TM), Multi-Cure Glass lonomer Band Cement (TM), and Transbond Plus Light Cure Band Adhesive (TM)) were prepared and the samples were extracted in 3 mL of Basal Medium Eagle with 10% newborn calf serum for 24 hours. The L929 cells were plated (25,000 cells/mL) in wells of 96-well dishes and maintained in a humidified incubator for 24 hours at 37 degrees C, 5% CO(2), and 95% air. After 24-hour incubation of the cells, the incubation medium was replaced by the immersed medium in which the samples were stored. Then L929 cells were incubated in contact with eluates for 24 hours. The cell mitochondrial activity was evaluated by the methyltetrazolium test. Twelve wells were used for each specimen, and methyltetrazolium tests were applied two times. The data were statistically analyzed using one-way analysis of variance and Tukey Honestly Significantly Different tests. Results: Results with L929 fibroblasts demonstrated that all freshly prepared resin-modified orthodontic band adhesive materials reduced vital cell numbers (P > .05), in comparison to the control group. Our data demonstrate that all materials showed significant cytotoxicity compared to the control group. Conclusions: The results indicate that all materials showed significant cytotoxicity compared to the control group, and further studies using different test methods are needed for all resin-modified orthodontic band adhesives. (Angle Orthod. 2010;80:890-895.)Öğe Cytotoxicity Evaluation of Bioresorbable Fixation Screws on Human Gingival Fibroblasts and Mouse Osteoblasts by Real-Time Cell Analysis(W B Saunders Co-Elsevier Inc, 2015) Yolcu, Umit; Alan, Hilal; Malkoc, Siddik; Bozkurt, Serife Buket; Hakki, Sema SezginPurpose: To evaluate the effects of bioresorbable fixation screws (BFSs) on human gingival fibroblast (HGF) and mouse osteoblast (MC3T3-E1) cell viability. Materials and Methods: The KLS Martin SonicPins Rx, Synthes RapidSorb Cortex Screws, and Inion CPS Bioabsorbable Fixation System each were incubated in Dulbecco's Modified Eagle Medium for 72 hours according to ISO 10993-5 standards. A real-time cell analyzer was used to evaluate cell survival. After seeding 200-mu L cell suspensions in the wells of an E-plate View 96, HGF and MC3T3-E1 cells were treated with the bioactive components released by the bioresorbable materials and monitored every 15 minutes for 96 hours. Statistical significance was determined using 1-way analysis of variance and Tukey-Kramer tests. Results: There were significant differences in the HGF responses to the untreated control conditions and the Synthes (P < .01), Inion (P < .05), and KLS Martin (P < .05) treatments over 48 hours. The Synthes (P < .01) and Inion (P < .01) treatments produced lower HGF cell index values than the untreated control at 72 hours, whereas the KLS Martin treatment did not. When left to elute for 96 hours, there were no significant differences in values among the control and study groups for HGFs (P > .05). All tested BFSs decreased cell survival rates of M3T3C1 cells for 48 hours (P < .01), 72 hours (P < .001), and 96 hours (P < .001). Conclusion: Differences in the sensitivities of the 2 tested cell lines to the different BFSs might be the result of the different materials used to manufacture the screws. These results provide fundamental knowledge and new insights for the future design and development of new biocompatible BFSs for oral and maxillofacial surgery. (C) 2015 American Association of Oral and Maxillofacial SurgeonsÖğe Dietary arginine silicate inositol complex inhibits periodontal tissue loss in rats with ligature-induced periodontitis(Dove Medical Press Ltd, 2016) Dundar, Serkan; Eltas, Abubekir; Hakki, Ema S.; Malkoc, Siddik; Uslu, M. Ozay; Tuzcu, Mehmet; Komorowski, JamesThe purpose of this study was to induce experimental periodontitis in rats previously fed diets containing arginine silicate inositol (ASI) complex and examine the biochemical, immunological, and radiological effects. Fifty two 8-week-old female Sprague Dawley rats were equally divided into four groups. The control group included those fed a standard rat diet with no operation performed during the experiment. The periodontitis, ASI I, and ASI II groups were subjected to experimental periodontitis induction for 11 days after being fed a standard rat diet alone, a diet containing 1.81 g/kg ASI complex, or a diet containing 3.62 g/kg ASI complex, respectively, for 8 weeks. Throughout the 11-day duration of periodontitis induction, all rats were fed standard feed. The rats were euthanized on the eleventh day, and their tissue and blood samples were collected. In the periodontitis group, elevated tissue destruction parameters and reduced tissue formation parameters were found, as compared to the ASI groups. Levels of enzymes, cytokines, and mediators associated with periodontal tissue destruction were lower in rats fed a diet containing ASI complex after experimental periodontitis. These results indicate that ASI complex could be an alternative agent for host modulation.Öğe Dietary boron does not affect tooth strength, micro-hardness, and density, but affects tooth mineral composition and alveolar bone mineral density in rabbits fed a high-energy diet(Elsevier Gmbh, 2015) Hakki, Sema S.; Malkoc, Siddik; Dundar, Niyazi; Kayis, Seyit Ali; Hakki, Erdogan E.; Hamurcu, Mehmet; Baspinar, NuriThe objective of this study was to determine whether dietary boron (B) affects the strength, density and mineral composition of teeth and mineral density of alveolar bone in rabbits with apparent obesity induced by a high-energy diet. Sixty female, 8-month-old, New Zealand rabbits were randomly assigned for 7 months into five groups as follows: (1) control 1, fed alfalfa hay only (5.91 MJ/kg and 57.5 mg B/kg); (2) control 2, high energy diet (11.76 MJ and 3.88 mg B/kg); (3) B10, high energy diet + 10 mg B gavage/kg body weight/96 h; (4) B30, high energy diet + 30 mg B gavage/kg body weight/96 h; (5) B50, high energy diet + 50 mg B gavage/kg body weight/96 h. Maxillary incisor teeth of the rabbits were evaluated for compression strength, mineral composition, and micro-hardness. Enamel, dentin, cementum and pulp tissue were examined histologically. Mineral densities of the incisor teeth and surrounding alveolar bone were determined by using micro-CT. When compared to controls, the different boron treatments did not significantly affect compression strength, and micro-hardness of the teeth, although the B content of teeth increased in a dose-dependent manner. Compared to control 1, B50 teeth had decreased phosphorus (P) concentrations. Histological examination revealed that teeth structure (shape and thickness of the enamel, dentin, cementum and pulp) was similar in the B-treated and control rabbits. Micro CT evaluation revealed greater alveolar bone mineral density in B10 and B30 groups than in controls. Alveolar bone density of the B50 group was not different than the controls. Although the B treatments did not affect teeth structure, strength, mineral density and micro-hardness, increasing B intake altered the mineral composition of teeth, and, in moderate amounts, had beneficial effects on surrounding alveolar bone. (C) 2014 Elsevier GmbH. All rights reserved.Öğe Effects of contemporary orthodontic composites on tooth color following short-term fixed orthodontic treatment: a controlled clinical study(Tubitak Scientific & Technological Research Council Turkey, 2015) Corekci, Bayram; Toy, Ebubekir; Ozturk, Firat; Malkoc, Siddik; Ozturk, BoraBackground/aim: To determine the color alterations of natural teeth associated with different orthodontic composites used in comprehensive short-term treatment. Materials and methods: Twenty-two patients were treated with fixed appliances and 22 untreated subjects were also evaluated. Lower incisors were bonded with different orthodontic composites: 42 with Grengloo, 41 with Light Bond, 31 with Kurasper F, and 32 with Transbond XT. The color parameters of the Commission Internationale de l'Eclairage (CIE) were measured for each tooth with a spectrophotometer. Color assessment in relation to time, adhesive material, and their interaction was made with 2-way mixed analysis of variance (ANOVA) and 1-way ANOVA for the color differences (Delta E*). Further analyses were done using Tukey's honestly significant difference tests and paired-samples t-tests. Results: The color of teeth was affected by treatment. The mean L* and a* values increased, whereas the mean b* values decreased. Total color differences of teeth demonstrated visible color changes clinically after treatment, ranging from 1.12 to 3.34 Delta E units. However, there were no significant differences for color of enamel. Conclusion: Teeth may be discolored with fixed appliances during treatment. Moreover, contemporary orthodontic composites have similar effects of enamel discoloration.Öğe Effects of Different Combinations of Er:YAG Laser-Adhesives on Enamel Demineralization and Bracket Bond Strength(Mary Ann Liebert, Inc, 2016) Cokakoglu, Serpil; Nalcaci, Ruhi; Usumez, Serdar; Malkoc, SiddikObjective: The purpose of this study was to investigate the demineralization around brackets and shear bond strength (SBS) of brackets bonded to Er:YAG laser-irradiated enamel at different power settings with various adhesive systems combinations. Methods: A total of 108 premolar teeth were used in this study. Teeth were assigned into three groups according to the etching procedure, then each group divided into three subgroups based on the application of different adhesive systems. There were a total of nine groups as follows. Group 1: Acid + Transbond XT Primer; group 2: Er:YAG (100 mJ, 10 Hz) etching + Transbond XT Primer; group 3: Er:YAG (200 mJ, 10 Hz) etching + Transbond XT Primer; group 4: Transbond Plus self-etching primer (SEP); group 5: Er:YAG (100 mJ, 10 Hz) etching + Transbond Plus SEP; group 6: Er:YAG (200 mJ, 10 Hz) etching + Transbond Plus SEP; group 7: Clearfil Protect Bond; group 8: Er:YAG (100 mJ, 10 Hz) etching + Clearfil Protect Bond; group 9: Er:YAG (200 mJ, 10 Hz) etching + Clearfil Protect Bond. Brackets were bonded with Transbond XT Adhesive Paste in all groups. Teeth to be evaluated for demineralization and SBS were exposed to pH and thermal cyclings, respectively. Then, demineralization samples were scanned with micro-CT to determine lesion depth values. For SBS test, a universal testing machine was used and adhesive remnant was index scored after debonding. Data were analyzed statistically. Results: No significant differences were found among the lesion depth values of the various groups, except for G7 and G8, in which the lowest values were recorded. The lowest SBS values were in G7, whereas the highest were in G9. The differences between the other groups were not significant. Conclusions: Er:YAG laser did not have a positive effect on prevention of enamel demineralization. When two step self-etch adhesive is preferred for bonding brackets, laser etching at 1 W (100 mJ, 10 Hz) is suggested to improve SBS of brackets.Öğe The effects of hesperidin on idiopathic pulmonary fibrosis evaluated by histopathologial-biochemical and micro-computed tomography examinations in a bleomycin-rat model.(Allied Acad, 2016) Gormeli, Cemile Ayse; Sarac, Kaya; Ciftci, Osman; Timurkaan, Necati; Malkoc, SiddikIdiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive parenchymal lung disease. The pathology is characterized by recurrent injury to microscopic alveolar epithelial cells. These injuries activate inflammatory cells, resulting in the proliferation of fibroblasts and alveolar tissue damage. Interstitial inflammation, advanced oxidative stress, and abnormal antioxidant activity were demonstrated to be the main causes of IPF. Hesperidin (HP) is a bioflavonoid with anti-inflammatory, antioxidant, anticarcinogenic, and analgesic actions. HP may be able to prevent pulmonary fibrosis, and may ultimately lead to healthy lung function. We hypothesized that HP could prevent Bleomycin (BLC)-induced pulmonary fibrosis due to its biochemical, antioxidant, and anti-inflammatory properties and may ultimately lead to healthy lung function. Based on these findings, we hypothesized that HP could prevent BLC-induced pulmonary fibrosis due to its biochemical, antioxidant, and anti-inflammatory properties. The animals were divided into 4 groups with 14 rats per group. The experimental treatments were as follows: Control, BLC, HP, and BLC+HP. Six of the 14 lungs in each group were sent for micro CT analysis. The remaining 8 lung specimens were harvested for histopathological and biochemical analyses. BLC-treated rats showed marked histopathological changes in the lungs. In these rats, thickening of interalveolar septa due to macrophage and lymphocyte infiltration, as well as fibroblast proliferation, were observed. Histopathological changes were less severe in the BLC+HP group compared with the BLC group. HP treatment led to a decrease in lipid peroxidation and an increase in antioxidant status compared with the BLC group. Also micro-CT showed a significant positive correlation with histopathological and biochemical results. To the best of our knowledge, this is the first study to evaluate the beneficial effects of HP against pulmonary fibrosis using histopathological, biochemical, and micro-CT analyses and HP successfully minimized the severity of BLC-induced lung injury, which was used as a model for IPF.Öğe Effects of staining solutions on the discoloration of orthodontic adhesives: An in-vitro study(Mosby-Elsevier, 2010) Corekci, Bayram; Irgin, Celal; Malkoc, Siddik; Ozturk, BoraIntroduction: Our aim was to evaluate the effects of staining solutions on the discoloration of orthodontic adhesives. Methods: Six orthodontic adhesives were investigated (Transbond XT [3M Unitek, Monrovia, Calif, USA], Heliosit Orthodontic [Ivoclar Vivadent, Liectenstein], Light Bond [Reliance Orthodontic Products, Itasca, IL, USA], Bisco Ortho [Bisco, Schamburg, IL, USA], Quick Cure [Reliance Orthodontic Products, Itasca, IL, USA], and Filtek Supreme XT [3M ESPE, St Paul, Minn, USA]), and 5 beverages (tea, cola, coffee, red wine, and yogurt). Sixty specimens were prepared. Five specimens from each group were stored in each of the 5 staining solutions. The 5 remaining specimens from each group served as the controls and were stored in distilled water. The specimens were immersed in staining solutions and water at 37 degrees C +/- 1 degrees C for 5 days. The test period was 25 days. Before and after the test period, color measurements were carried out with a spectrophotometer, and color changes (Delta E*) were calculated. Statistical differences were evaluated by using analysis of variance (ANOVA) and the Tukey HSD tests. Results: Adhesive materials, staining agents, and their interactions were found to play statistically significant roles (P <0.001) in color changes. Among the adhesive materials, the Light Bond water control group consistently showed the lowest Delta E* value for all materials, and the Filtek Supreme XT group showed the highest Delta E* value for all materials. After the in-vitro experimental process for staining solutions and water, unsatisfactory color stability was observed for the conventional adhesive systems except for Light Bond, Transbond XT, and Bisco Ortho water control group (Delta E* >3.7), respectively. Conclusions: In esthetically critical areas, discoloration of adhesive materials for fixed orthodontics can cause patient dissatisfaction. Orthodontic composites will discolor from staining beverages during their lifespan. (Am J Orthod Dentofacial Orthop 2010;138:741-6)Öğe Effects of Time Delay on Degree of Conversion of Contemporary Orthodontic Band Adhesives(Aves Press Ltd, 2013) Corekci, Bayram; Toy, Ebubekir; Malkoc, Siddik; Ozturk, Bora; Gunduz, S. BenizObjective: For prolonged use in the oral cavity, orthodontic band adhesives should have certain physical properties to ensure the best clinical performance. The degree of conversion (DC) of orthodontic band adhesives has been found to affect their mechanical properties. The aim of this study was to investigate the effects of time delay on the DC of orthodontic band adhesives. Materials and Methods: Fourier-transform infrared spectroscopy was used to evaluate the DC of 3 adhesives (Bisco Ortho Band Paste LC, Multi Cure Glass Ionomer Band Cement, Transbond Plus Light Cure Band Adhesive) immediately after they had been polymerized and stored in artificial saliva at 37 +/- 1 degrees C for 30 days. Thirty disc-shaped specimens (10 for each adhesive) were fabricated in Teflon molds (6.0 x 1.0 mm). The samples for each adhesive were divided further into 2 groups (n=5). Results: The DC was significantly influenced by the band adhesive type (p < 0.05), and there were significant differences among band adhesive types for the DC after 30 days. Conclusion: The value of the DC could change with time delay.Öğe Evaluation of the effects of the low-level laser therapy on swelling, pain, and trismus after removal of impacted lower third molar(Biomed Central Ltd, 2016) Alan, Hilal; Yolcu, Umit; Koparal, Mahmut; Ozgur, Cem; Ozturk, Seyit Ahmet; Malkoc, SiddikBackground: In current study we aimed to examine the effect of a low-level laser therapy on the pain, mouth opening and swelling of patients whose impacted 3rd molar tooth was extracted in addition measurement volumetrically to the edema with 3dMD face system. Methods: It was surveyed 15 patients who had bilateral symmetric lower 3rd molars. Surgical sides of patients were randomly separated into two groups: the study group and the control group. It was applied extra oral low-level laser therapy (LLLT, 0.3 W, 40 s, 4 J/cm(2)) to the study group (n = 15) after the surgical operation and on the 2nd day. Only routine postoperative recommendation (ice application) was made in the control (n = 15) group. The maximum mouth opening, pain level and facial swelling evaluated. 3dMD Face r (3dMD, Atlanta, GA) Photogrammetric System was used to evaluate volumetric changes of the swelling. Results: There was no statistically significant difference in the edema and interincisal opening between the groups and the pain level in the laser group was significantly lower than in the control group on the 7th postoperative day. Conclusions: Although there were decreasing trismus, swelling, and pain level, with this LLLT, there was significant difference only in the 7th day pain level in the laser group compared with the control group.Öğe In-vitro assessment of temperature rise in the pulp during orthodontic bonding(Mosby-Elsevier, 2010) Malkoc, Siddik; Uysal, Tancan; Usumez, Serdar; Isman, Eren; Baysal, AsliIntroduction: In this in-vitro study, we evaluated the temperature changes in the pulp chamber during bracket bonding using 4 different light sources. Methods: Eighty intact extracted maxillary central incisors were used. The teeth were divided into 4 groups of 20 teeth each. Brackets (Mini Twin, Dentaurum, Ispringen, Germany) were bonded with Transbond XT (3M Unitek, Monrovia, Calif) adhesive and light cured with low-intensity halogen light for 40 seconds, high-intensity halogen light for 40 seconds, light-emitting diode (LED) light for 20 seconds, and plasma arc light (PAC) for 6 seconds. Light curing was performed 5 mm from tooth surfaces. A J-type thermocouple wire was positioned in the center of the pulp chamber. The results were analyzed with analysis of variance (ANOVA) and the Tukey HSD test. Results: ANOVA and the Tukey HSD test showed that pulp chamber temperature changes were influenced by the type of light source. All groups showed significant differences between each other (P <0.001). The intrapulpal temperature changes induced by different light sources were the following: high-intensity halogen (6.84 degrees C +/- 2.44 degrees C), low-intensity halogen (4.71 degrees C +/- 0.96 degrees C), LED (2.95 degrees C +/- 1.12 degrees C), and PAC (0.96 degrees C +/- 0.83 degrees C). Conclusions: High-and low-intensity halogen light induced significantly higher intrapulpal temperature changes than did the LED and PAC. Except for the high intensity halogen light, orthodontic bonding with light-curing units did not exceed the critical 5.5 degrees C rise in temperature reported to produce pulpal damage. (Am J Orthod Dentofacial Orthop 2010; 137: 379-83)Öğe The incidence of canine transmigration and tooth impaction in a Turkish subpopulation(Oxford Univ Press, 2010) Aktan, Ali Murat; Kara, Sami; Akgunlu, Faruk; Malkoc, SiddikThe purpose of this study was to determine the incidence of transmigrated maxillary and mandibular canine teeth and also of the other impacted teeth in a Turkish subpopulation. Five thousand consecutive panoramic radiographs taken of patients who attended the Department of Oral Diagnosis and Radiology, Selcuk University, for routine examination between 2005 and 2007 were examined to identify incidences of transmigrated and impacted teeth. Demographic information of all patients was also recorded. Transmigrations were categorized according to the classification of Mupparapu. The effect of age, gender, and sidedness (left or right side) on the recorded abnormality was evaluated using a t-test. The incidence of transmigrated upper and lower canine teeth was found to be 0.34 per cent [17 patients, 12 females/5 males, with a mean age of 34 years (range 16-76 years)] and 0.14 per cent [7 patients, 4 females/3 males, with a mean age of 37.1 years (range 17-62 years)]. The incidence of tooth impaction was 2.94 per cent [147 patients, 101 females/46 males, with a mean age of 29.7 years (range 15-80 years)]. The most frequently impacted tooth was the upper canine followed by the lower canine, lower second premolar, and upper second premolar. No incidence of maxillary first molar impaction was found. Gender and sidedness did not show a statistical significance on the recorded abnormality (P = 0.22 and P = 0.48, respectively). However, in the 15-29 year age group, this was statistically different (P < 0.05). The incidence of transmigration of impacted mandibular canine teeth was greater than other teeth. With the increased use of panoramic radiographs, it is inevitable that diagnosis of such anomalies will increase.Öğe Maxillary and mandibular mesiodistal tooth sizes among different malocclusions in a sample of the Turkish population(Oxford Univ Press, 2011) Malkoc, Siddik; Basciftci, Faruk Ayhan; Nur, Metin; Catalbas, BulentThe purpose of this study was to establish normative data for mesiodistal tooth crown dimensions with respect to malocclusions and gender differences in Turkish sample. The subjects were randomly selected and assigned to three malocclusion groups according to Angle's classification. Each group consisted of 100 individuals between the ages of 13 and 18 years with the following distribution: Class I, 42 males and 58 females; Class II, 52 males and 48 females; and Class III, 51 males and 49 females. An electronic digital calliper was used to measure the mesiodistal tooth width from the right second permanent molar to the left second permanent molar on both upper and lower study casts. For statistical evaluation, one-and two-way analyses of variance and post hoc Tukey's honestly significant difference (HSD) tests were performed. There were statistically significant differences for the maxillary canine (P < 0.001), first premolar (P < 0.05), second molar (P < 0.05), and mandibular canine (P < 0.01) for males, and for all maxillary teeth and the mandibular central (P < 0.05), canine (P < 0.001), and first premolar (P < 0.05) teeth in females among the malocclusion groups. When Angle's classification was evaluated, significant differences were determined, except for the first and second mandibular molars. All mesiodistal widths were also found to be statistically different according to gender dimorphism. A significant relationship was found between mesiodistal tooth size, Angle's classification, and gender. Therefore, tooth dimensions may play a crucial role in treatment planning and in achieving satisfactory interdigitation of the upper and lower dentition following the completion of orthodontic treatment.Öğe Micro-CT evaluation of microleakage under orthodontic ceramic brackets bonded with different bonding techniques and adhesives(Oxford Univ Press, 2016) Ozturk, Firat; Ersoz, Mustafa; Ozturk, Seyit Ahmet; Hatunoglu, Erdem; Malkoc, SiddikThe aim of this study was to evaluate microleakage under orthodontic ceramic brackets bonded with direct and different indirect bonding techniques and adhesives using micro-computed tomography. A total of 30 human maxillary premolars were randomly separated into five groups with six teeth in each group. In group I, teeth were bonded directly with Transbond XT (3M Unitek). In group II, group III, group IV, and group V, teeth were bonded through an indirect technique with Custom I.Q. (Reliance Orthodontic Products), Sondhi Rapid-Set (3M Unitek), RMbond (RMO), and Transbond IDB (3M Unitek), respectively, following the manufacturer's instructions. Micro-CT system model 1172 of Skyscan (Kontich, Belgium) was used to scan all samples. NRecon (Skyscan) version 1.6, CT-Analyser V.1.11 (Skyscan), and TView (SkyScan, Bvba) software programs were used for microleakage evaluation. Microleakage values between the test groups were assessed using the Kruskal-Wallis test, while the Wilcoxon signed rank test was used for within-group comparisons. The level of significance was set at P < 0.05. According to the Kruskal-Wallis analysis of variance test, there were no significant differences among the tested groups, with regard to volume and percentage (microleakage/region of interest x 100) of microleakage values (P < 0.05). The Wilcoxon signed rank test showed that coronal microleakage volume and percentage values significantly differed for RMbond and Transbond IDB groups. In the study, only ceramic brackets were used and microleakage into mini gaps did not show up on the micro-CT image because 50% silver nitrate solution could not penetrate into mini gaps which are smaller than silver nitrate particles. Use of direct and indirect bonding techniques with different adhesives did not significantly affect the amount of microleakage.Öğe Microcomputed tomography evaluation of white spot lesion remineralization with various procedures(Mosby-Elsevier, 2016) Kucuk, Eyup Burak; Malkoc, Siddik; Demir, AbdullahIntroduction: The aim of this study was to use microcomputed tomography to evaluate the effects on white spot lesions of 3 remineralizing agents compared with artificial saliva (Inonu University, Malatya, Turkey). The agents were GC Tooth Mousse (GC International, Itabashi-ku, Tokyo, Japan), 50-ppm sodium fluoride solution (Inonu University, Malatya, Turkey), and Clinpro 5000 (3M ESPE Dental Products (St Paul, Minn). The experimental and control teeth were stored in artificial saliva. Methods: Forty-four extracted premolars were divided into 4 groups of 11 teeth each (3 experimental groups and 1 control group). After white spot lesions were created on the teeth, a remineralizing agent was applied. Microcomputed tomography scanning was performed at the following times: T0 (sound enamel), T1 (day 0, when the white spot lesion was formed), T2 (day 15), and T3 (day 30). Volume, depth, surface area, and mineral density changes of the white spot lesions were evaluated at different time points using CTAn software (SkyScan; Bruker, Kontich, Belgium). Results: GC Tooth Mousse and Clinpro 5000 improved all measurements after 30 days. However, Clinpro 5000 was not as effective in reducing lesion depth as it was in the other parameters. The artificial saliva group and the 50-ppm sodium fluoride solution did not show significant effects in the regression of the white spot lesions at the end of the 30-day experiment. Conclusions: GC Tooth Mousse and Clinpro 5000 were more effective in remineralization of white spot lesions than sodium fluoride solution and artificial saliva. They can be preferred for use clinically. Microcomputed tomography is a novel and effective method that shows promise in accurately evaluating white spot lesions and remineralization.Öğe Modification of Maxillary Sinus Floor With Orthodontic Treatment and Implant Therapy: A Case Letter(Allen Press Inc, 2014) Saglam, Mehmet; Akman, Serhan; Malkoc, Siddik; Hakki, Sema S.[Abstract Not Available]
