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    Evaluation of Post-traumatic Stress, Depression, and Anxiety Levels in Survivors of the 2023 Kahramanmaraş Türkiye Earthquakes at the 12th Month After the Event
    (Cambridge Univ Press, 2025) Cansel, Neslihan; Sandikli, Hatice; Melez, Sahide Nur Ipek; Sandikli, Mustafa; Cicek, Ipek Balikci; Kayhan Tetik, Burcu
    Objectives On February 6, 2023, 7.7 and 7.6 magnitude earthquakes struck southeastern T & uuml;rkiye, affecting 11 provinces and causing significant losses. This study aims to assess the mental health status of survivors in the twelfth month after the earthquake.Methods A cross-sectional study was conducted using an online survey with the virtual snowball sampling method. The survey included sociodemographic data, previous traumas, earthquake-related experiences, and the Post-Earthquake Trauma Level Determining Scale (PETLDS) and Hospital Anxiety and Depression Scale.Results The study included 2544 participants. The mean PETLDS score was 58.14 +/- 18.18, indicating that the participants were highly traumatized. Among them, 59.5% had high levels of post-traumatic symptoms, 44.2% had high anxiety, and 61% had high depression symptoms. 35.77% of participants displayed a co-occurrence of post-traumatic stress along with anxiety and depression. Female gender was the strongest predictor of high-level trauma and anxiety, while a history of psychiatric disorder was the strongest predictor of depression. Multiple logistic regression analysis indicated that symptoms were predicted by low income, low education level, smoking, comorbid chronic diseases, past traumatic experiences, the loss or injury of a loved one due to the earthquake, personal injury, temporary displacement, and damage to homes and workplaces.Conclusions The findings suggest that one year after the earthquake, mental health problems are prevalent among survivors, highlighting the need for urgent psychiatric interventions.
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    Frequency and predictors of coronavirus anxiety in psychiatric patients and healthy people and its effect on treatment compliance during the pandemic
    (2021) Cansel, Nesihan; Ünal, Ahmet; Ekici Onsoz, Saadet; Akan, Mustafa; Gonenir Erbay, Lale; Melez, Sahide Nur Ipek
    Coronavirus-19 has caused anxiety around the world. Although anxiety is inherent in pandemics, it can have serious consequences when it is chronic and disproportionate. It is possible situation affect the vulnerable population with mental illness more. This study compares the frequency and predictors of coronavirus anxiety among psychiatric patients and the healthy group and evaluates its effects on treatment compliance. A cross-sectional study was conducted on 285 psychiatric patients who applied to the psychiatry outpatient clinic and 86 healthy people between 15 July – 30 September 2020. Coronavirus Anxiety Scale was applied with a questionnaire that investigated demographic characteristics, experiences with the pandemic and treatment compliance. Coronavirus anxiety was detected in 8.4% of the patients and 9.3% of the healthy group. 34% of the patients didn’t come to checkups regularly, the most common reason for this was their fear of the pandemic (56.7%). Their anxiety scores were also high. Female gender, comorbid disease and being quarantined were associated with an increased coronavirus anxiety scale score in patients while advanced age, retirement, divorced/widowed, having children, having comorbid disease, being tested for COVID-19 PCR and losing a relative due to COVID-19 increased the score in healthy group. Coronavirus anxiety disrupts the compliance of psychiatric patients with treatment and may cause the disease to exacerbate. Therefore, there is a need to develop special treatment approaches in the follow-up of psychiatric patients.
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    Prevalence and predictors of psychological response during immediate COVID-19 pandemic
    (Wiley-Hindawi, 2021) Cansel, Neslihan; Ucuz, Ilknur; Arslan, Ahmet Kadir; Kayhan Tetik, Burcu; Colak, Cemil; Melez, Sahide Nur Ipek; Sule Gumustakim, Raziye
    Aim COVID-19 pandemic has created a serious psychological impact worldwide since it has been declared. This study aims to investigate the level of psychological impacts of the COVID-19 pandemic on the Turkish population and to determine related factors. Methods The study was carried out by an online questionnaire using the virtual snowball sampling method. The sociodemographic data were collected on the following subjects: participants' experience on any signs of infection within the last month, the history of COVID-19 contact-treatment-quarantine, level of compliance with precautionary measures, the sources of information and level of knowledge about the pandemic process and their belief levels on the knowledge they acquire. Besides, the questions that take place in the Depression, Anxiety and Stress Scale-21 (DASS-21), and Impact of Events Scale-Revised (IES-R) were asked to participants. Results Of the 3549 participants, anxiety was found in 15.8%, depression in 22.6%, stress in 12.9%, and psychological trauma in 20.29% based on moderate and above levels. Female gender, young age, higher education level, being single, high monthly income, presence of psychiatric illness, a large number of people living together, having any signs of infection, and contact history with COVID-19 infected person or contaminated object are identified as risk factors that may increase psychological impact. Compliance with the rules was found to reduce the risk of psychological response. Conclusions The risk factors for the psychological impact of the COVID-19 pandemic, and acknowledging these factors can help to formulate the interventions to reduce the stress levels of the population.
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    Reply to the Letter to the Editor: Interpretation of the Relationship Between CHA2DS2-VASc and Anxiety in Anticoagulated Patients
    (Kare Publ, 2026) Cansel, Neslihan; Adiguzel, Muhammed Yasin; Melez, Sahide Nur Ipek; Bayramoglu, Adil
    [No abstract available]
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    The Effects of Warfarin and Novel Oral Anticoagulants on Depression and Anxiety in Patients with Non-Valvular Atrial Fibrillation
    (Kare Publ, 2025) Cansel, Neslihan; Adiguzel, Muhammed Yasin; Melez, Sahide Nur Ipek; Bayramoglu, Adil
    Objective: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia and has a detrimental impact on psychological well-being. This study aims to determine the prevalence of anxiety and depression in patients with non-valvular AF and to investigate the relationship between these psychological conditions and the treatment regimens administered. Method: This cross-sectional study included 255 individuals diagnosed with non-valvular AF who were treated between 2021 and 2022. Psychiatric evaluation was conducted using the Beck Depression Inventory and Beck Anxiety Inventory. Multivariate regression analysis was performed to identify predictors of depression and anxiety. Results: Of the patients included, 62 were on warfarin, 124 were on novel oral anticoagulants (NOACs), and 69 were not receiving any oral anticoagulant (OAC) therapy. Overall, 68.6% had depression and 64.7% had anxiety at a moderate or higher severity level. Although there was no notable variation in anxiety and depression scores between patients on NOACs and those not undergoing OAC treatment, the warfarin group had significantly higher scores than the other two groups. Age, anxiety, C-reactive protein (CRP) levels, and CHA2DS2-VASc scores (Congestive heart failure, Hypertension, Age >= 75 years, Diabetes mellitus, prior Stroke/transient ischemic attack-Vascular disease, Age 65-74 years, Sex category) all positively correlated with the severity of depression. Anxiety, in turn, was positively associated with age, depression, and CHA2DS2-VASc scores, and negatively associated with ejection fraction. Regression analysis revealed a strong correlation between warfarin treatment and anxiety severity. Conclusion: The findings of this study suggest that warfarin treatment is associated with significant psychological effects in patients with AF. Considering that comorbid psychiatric disorders are linked to unfavorable prognosis and higher mortality, the development of appropriate intervention strategies that address psychological distress as part of the treatment process may provide substantial clinical benefits.