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    Evaluation of Nutritional Needs of Intensive Care Unit Patients by Clinical Pharmacists
    (Hacettepe University, Faculty of Pharmacy, 2024) Çakir A.; Memiş H.; Ülkü Gün Z.
    Malnutrition in intensive care unit (ICU) patients affects disease progression and prolongs hospital stays. In this study, it was aimed to present the recommendations of clinical pharmacists in terms of nutrition in ICU patients.This study was conducted in the ICU between November 2022 and January 2023. Clinical pharmacists counseled patients on nutrition according to guidelines. Basal energy expenditure was calculated using the Harris-Benedict formula, and the most appropriate nutritional product was selected for the patients. Descriptive analyses were performed with SPSS v27.0.Total number of patients and recommendations were 41 and 71, respectively. Hundred percent of the recommendations were accepted. According to the reasons, the recommendation rates were categorized as feeding started (9.86%), feeding stopped (1.41%), feeding dose increased-reduced (28.17%), protein amount increased-reduced (35.21%), management of nutritional complications (15.49%), and changes in administration (9.86%). Enema (54.54%) for constipation, prokinetic metoclopramide (36.36%), and discontinuation of parenteral nutrition due to hyperglycemia (9.09%) were recommended for the management of nutritional complications. Examples of suggestions and explanations made regarding the nutritional status of the patients were given.In this study, recommendations were made for most ICU patients to eat more calories and protein. Clinical pharmacists can prevent malnutrition with other healthcare professionals. © 2024, Hacettepe University, Faculty of Pharmacy. All rights reserved.
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    Evaluation of the Appropriateness of Antimicrobial Drug Dosages in Intensive Care Unit Patients
    (Hacettepe University, Faculty of Pharmacy, 2024) Memiş H.; Çakir A.; Özdemir N.; Gün Z.Ü.
    The purpose of this study was to investigate the factors that required dose adjustments of antimicrobial drugs in intensive care unit (ICU) patients and to identify the drugs that required the most dose adjustments. The current prospective study was conducted in the reanimation ICU with 26-bed capacity of a university-af-filiated hospital from September to December 2022. Two clinical pharmacists on duty examined patients’ antimicrobial drug dosages daily. The acceptance status of the recommendations and the patients’ demographic information were recorded. The study involved 133 ICU patients, and antimicrobial drug recommendations were made for 48 patients, 31 (64.6%) of whom were male. The median (IQR) age of the 48 patients was 67 (54–77). The count of recommendations was 94, and the acceptance rate was 100%. The recommendation rates were as follows: 71.3% for renal function, 11.7% for presence of continuous renal replacement therapy, 10.6% for indication, 4.3% for body weight, and 2.1% for loading dose. The top 3 drugs for which recommendations were made the most were colistin (21.3%), meropenem (18.1%), and piperacillin-tazobactam (12.8%). The most troublesome drug was colistin, which is frequently used to treat Acinetobacter pneumonia. Clinical pharmacist and physician collaboration may help rationalize ICU antimicrobial drug use. © 2024, Hacettepe University, Faculty of Pharmacy. All rights reserved.