Yazar "Miman, Ozlem" seçeneğine göre listele

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    A demodicosis case which responded to systemic ivermectin
    (John Libbey Eurotext Ltd, 2009) Karincaoglu, Yelda; Miman, Ozlem; Kalayci, Bulent; Aycan, Ozlem Makbule; Atambay, Metin
    [Abstract Not Available]
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    Does Toxoplasma gondii play a role in obsessive-compulsive disorder? Response
    (Elsevier Ireland Ltd, 2012) Miman, Ozlem; Mutlu, Elif Aktan; Ozcan, Ozlem; Atambay, Metin; Karlidag, Rifat; Unal, Suheyla
    [Abstract Not Available]
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    Is there any role of Toxoplasma gondii in the etiology of obsessive-compulsive disorder?
    (Elsevier Ireland Ltd, 2010) Miman, Ozlem; Mutlu, Elif Aktan; Ozcan, Ozlem; Atambay, Metin; Karlidag, Rifat; Unal, Suheyla
    Obsessive-compulsive disorder (OCD) is a common psychiatric illness. Although the aetiology of OCD is still unknown, the family-genetic data show that familial forms of OCD may be associated with a specific genetic susceptibility. Recent investigations have associated development of OCD with infectious illness. Toxoplasmic encephalitis (TE) is a common presentation of Toxoplasma gondii infection of the central nervous system (CNS). The most commonly affected CNS region in TE is the cerebral hemisphere, followed by the basal ganglia, cerebellum and brain stem. The basal ganglia has been implicated in the development of OCD. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD. We selected 42 patients with OCD and 100 healthy volunteers, and investigated the sero-positivity rate for anti-Toxoplasma IgG antibodies by Enzyme Linked Immunosorbent Assay (ELISA). The sero-positivity rate for anti-T. gondii IgG antibodies among OCD patients (47.62%) was found to be significantly higher than the rate in healthy volunteers (19%). This is the first report to examine a potential association between Toxoplasma infection and OCD. The main finding of the present study is an increased level of IgG antibodies to T. gondii in OCD patients when compared with the level in healthy controls. There might be a causal relationship between chronic toxoplasmosis and the aetiology of OCD. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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    Toxoplasma gondii - obsessive -compulsive disorder relationship: is it different in children?
    (Taylor & Francis Ltd, 2018) Miman, Ozlem; Ozcan, Ozlem; Unal, Sueheyla; Atambay, Metin
    Background and aim: Obsessive-compulsive disorder (OCD) is a common neuropsychiatric illness. Although the etiology of OCD is still unknown, recent investigations have associated development of OCD with infectious illness. Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes infection of the central nervous system. In the last decade, a lot of researches have focused on the possible relationship between exposure to T. gondii and neuropsychiatric disorders such as schizophrenia. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD in children and adolescents.Methods: We selected 55 patients with OCD (aged between 7 and 16 years) and 59 healthy children and adolescents (aged between 7 and 16 years), and investigated the seropositivity rate for anti-Toxoplasma IgG antibodies by enzyme-linked immunosorbent assay.Results: The seropositivity rate for anti-T. gondii IgG antibodies among OCD patients (21.82%) was found to be higher than the rate in control group (15.25%). However, the difference between the OCD group and the control group was not statistically significant (p>.05).Conclusion: In contrast to studies in adult patients, the results of this study do not support the relationship between T. gondii and OCD children and adolescents.
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    Toxoplasma gondii - obsessive -compulsive disorder relationship: is itdifferent in children?
    (Taylor & francıs ltd, 2-4 park square, mılton park, abıngdon or14 4rn, oxon, england, 2018) Miman, Ozlem; Ozcan, Ozlem; Unal, Sueheyla; Atambay, Metin
    Background and aim: Obsessive-compulsive disorder (OCD) is a common neuropsychiatric illness. Although the etiology of OCD is still unknown, recent investigations have associated development of OCD with infectious illness. Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes infection of the central nervous system. In the last decade, a lot of researches have focused on the possible relationship between exposure to T. gondii and neuropsychiatric disorders such as schizophrenia. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD in children and adolescents.Methods: We selected 55 patients with OCD (aged between 7 and 16 years) and 59 healthy children and adolescents (aged between 7 and 16 years), and investigated the seropositivity rate for anti-Toxoplasma IgG antibodies by enzyme-linked immunosorbent assay.Results: The seropositivity rate for anti-T. gondii IgG antibodies among OCD patients (21.82%) was found to be higher than the rate in control group (15.25%). However, the difference between the OCD group and the control group was not statistically significant (p>.05).Conclusion: In contrast to studies in adult patients, the results of this study do not support the relationship between T. gondii and OCD children and adolescents.