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    Brain MRS findings in neonates with hypothyroidism born to mothers living in iodine-deficient area
    (Karger, 2006) Akinci, Aysehan; Sarac, Kaya; Gungor, Serdal; Mungan, Ilke; Aydyn, Ozgur
    [Abstract Not Available]
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    Is edema in minimal change disease of childhood really hypovolemic?
    (Springer, 2008) Tabel, Yilmaz; Mungan, Ilke; Karakurt, Cemsit; Kocak, Gulendam; Gungor, Serdal
    Objectives In this study, we aimed to find out whether children with minimal change disease can be classified as hypervolemic by objective measures. Methods Eighteen children with minimal change disease diagnosed at our department between November 2005 and May 2007 were included in this study. All patients were newly diagnosed or relapsed but were steroid free for at least 6 months. In the first week of edema and when edema resolved (5-7 days after initiation of therapy), weight, height and blood pressure were obtained from all patients. Serum and plasma samples were taken following a starvation period of 12-14 h. The volume load of all patients was evaluated, measuring the inferior vena cava indices in each stage by echocardiography. Results Average weight at presentation was 8.5% higher than the ideal (dry) weight. There were significant differences between the first and post-treatment body weights, abdomen circumference, and systolic and diastolic blood pressure values (P < 0.05 for each). The inferior vena cava index (IVCI) values decreased significantly after diuretic treatment (P < 0.001), while inferior vena cava collapsibility index (IVCCI) values increased in the post-treatment period (P < 0.001). Conclusion We believe that a close follow-up of hypervolemic children with MCD, treated solely with easy-to-handle diuretics instead of I.V. albumin and diuretics may properly solve the edematous state in these patients.
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    Primary Lymphoedema at an Unusual Location Triggered by Nephrotic Syndrome
    (Acad Medicine Singapore, 2009) Tabel, Yilmaz; Mungan, Ilke; Sigirci, Ahmet; Gungor, Serdal
    Introduction: Lymphoedema results from impaired lymphatic transport leading to the pathologic accumulation of protein-rich lymphatic fluid in the interstitial space, most commonly in the extremities. Primary lymphoedema, a developmental abnormality of the lymphatic system, may become evident later in life when a triggering event exceeds the capacity of normal lymphatic flow. Clinical Picture: We present a 3-year-old nephrotic syndrome patient with an unusual localisation for primary lymphoedema. Treatment and Outcome: The patient was treated with conservative approach and she was cured. Conclusion: In this particular case, lymphoedema developed at an unusual localisation, which has not been recorded before.