Yazar "Ocakli, Birsen" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Delays in diagnosis in patients with pulmonary and extrapulmonary sarcoidosis
    (2019) Acarturk Tuncay, Eylem; Yalcinsoy, Murat; Gungor, Sinem; Selcuk, Engin Burak; Tokgoz Akyil, Fatma; Yavuz, Dilek; Sucu, Pakize; Alpaslan Bekir, Sumeyye; Ocakli, Birsen; Aksoy, Emine
    Aim: Sarcoidosis is a multisystemic disease with typical or atypical pulmonary and extra-pulmonary symptoms or frequently without symptoms. Presence of typical clinical findings and symptoms contribute to rapid diagnosis, whereas asymptomatic progression leads to delays in the diagnosis. The aim of this study was to investigate the delay in diagnosis in between patients with pulmonary and/or extra-pulmonary involvement and related symptoms and those without symptoms. Material and Methods: Patients in the sarcoidosis clinics between 2010-2015, were retrospectively evaluated. The cases were grouped according to the presence or absence of symptoms (pulmonary and/or extra-pulmonary). The groups were compared with regard to the delay in diagnosis. Results: Among the 300 patients, 209 (69%) were female. The mean age was 43±11.68. The disease was stage I in 67.3%, stage II in 23.7%, stage III in 5.7% and stage 0 in 3.3% of the patients. No significant difference was observed between symptomatic and asymptomatic patients with regard to total duration until diagnosis (p=0.78). A statistically significant difference was observed between patients groups with regard to physician-related delayed diagnosis(p=0.026). The mean delay in physician-related diagnosis was observed to be longer in asymptomatic cases (21.44 days) compared to patients with pulmonary symptoms (13.66 days)(p=0.036). In asymptomatic cases, the mean duration of physician-related delayed diagnosis (21.44 days) was observed to be longer in comparison with patients with extra-pulmonary symptoms (12.79 days)(p=0.016). In patient-related delayed diagnosis, no difference was observed between groups with regard to the duration until diagnosis(p=0.78). Conclusion: Comparison of delayed diagnosis between patients with or without pulmonary and/or extra-pulmonary symptoms revealed a longer duration of delay in asymptomatic cases compared to symptomatic cases. The timing of diagnosis is very important in sarcoidosis in order to reduce morbidity and mortality; a suspicious approach to asymptomatic patients will increase the possibility of diagnosis and prevent delayed diagnosis.Keywords: Sarcoidosis; diagnosis; delay; extrapulmonary symptoms.
  • Küçük Resim Yok
    Öğe
    Extrapulmonary Sarcoidosis withMultiple-Organ Involvement
    (2018) Aksoy, Emine Ebru; Tunçay, Eylem; Ocakli, Birsen; Bekir, Sümeyye Alparslan; Atik, Sinem Güngör; Tokgöz, Fatma Akyıl; Sucu, Pakize
    Objective: In cases of pulmonary sarcoidosis, extrapulmonary involvement is not uncom-mon. The skin, eyes, and lymph nodes are the most common sites of extrapulmonary in-volvement, and multiple organs may be involved at the same time. In this study, patients with extrapulmonary sarcoidosis were investigated in terms of the localization of involvement.Methods: Patients diagnosed with sarcoidosis between 1994 and 2015 were evaluated ret-rospectively. Demographic characteristics, symptoms, organ involvement, diagnostic meth-ods, and the length of time between the diagnosis of sarcoidosis and additional organ in-volvement were recorded. The patients were consulted to the departments of dermatology, ophthalmology, and cardiology, and a chest X-ray, high-resolution computed tomography, and abdominal ultrasound examinations were performed.Results: Extrapulmonary involvement was detected in 144 of a total of 337 sarcoidosis pa-tients. In 92% of those patients with extrapulmonary involvement, there was accompanying pulmonary involvement. Women made up 75% of the group, and the mean age was 43 years. The most commonly detected extrapulmonary involvement was of the skin (n=41), followed by erythema nodosum (n=37), and involvement of the liver (n=24), lymph nodes (n=20), spleen (n=18), and salivary/parotid gland (n=15). The most frequent diagnostic method used was mediastinoscopy (n=41), followed by a skin biopsy (n=23), and a transbronchial lung biopsy (n=19). Of the 26 (18%) patients who had multiple-organ involvement, 2 were diag-nosed as stage 0, 14 were stage 1, 9 were stage 2, and 1 was stage 3. The mean length of time before a diagnosis of extrapulmonary involvement was 24 days.Conclusion: If there is extrapulmonary involvement in a case of sarcoidosis, it should be kept in mind that more than 1 organ system may be involved and the relevant additional tests may be required.