Yazar "Oezdemir, Ismail" seçeneğine göre listele

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    Benzylic imidazolidinium, 3,4,5,6-tetrahydropyrimidinium and benzimidazolium salts
    (Wiley-V C H Verlag Gmbh, 2008) Yasar, Sedat; Oezdemir, Ismail; Cetinkaya, Bekir; Renaud, Jean-Luc; Bruneau, Christian
    Imidazoliidinium, tetrahydropyrimidinium and benzimidazolium. salts were prepared. Upon reaction with tBuOK, they generate carbene ligands, which were associated in situ to [RuCp*(MeCN)(3)]PF6 to produce ruthenium catalysts that are active for the substitution of allylic substrates by dimethyl of the N-heterocyclic structures, as well as that of the benzyhc N-substituents, on the reactivity and regioselectivity were examined. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).
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    Heck and suzuki reactions of aryl halides catalyzed by 1,3-dialkylimidazolinium/palladium
    (Science Press, 2008) Yasar, Sedat; Oezdemir, Ismail; Cetinkaya, Bekir
    New, sterically demanding 1,3-dialkylimidazolinium salts used as N-heterocyclic carbene precursors were synthesized and characterized. These salts, combined with palladium acetate, provided active catalysts for Heck and suzuki cross-coupling of aryl chlorides and bromides under mild conditions.
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    In Vitro Evaluation of Silver-NHC Complexes Against a Clinical Isolate of Acanthamoeba castellanii: Time- and Dose-Dependent Effects
    (Mdpi, 2025) Akin-Polat, Zuebeyda; Sahin, Neslihan; Hkiri, Shaima; Ly, Bui Minh Thu; Oezdemir, Ismail; Semeril, David
    The synthesis of a series of six chloro[N-alkyl-N-cinnamyl-benzimidazol-2-yliden]silver(I) complexes was successfully achieved, wherein allyl (3a), methoxymethyl (3b), benzyl (3c), 3-fluorobenzyl (3d), 4-fluorobenzyl (3e) and 4-methyl-benzyl (3f) substituents were grafted on the benzimidazole ring. The isolated silver N-heterocyclic carbene (NHC) complexes were identified by microanalyses and mass spectrometry and characterized by FT-IR and NMR spectroscopic techniques. Conclusive evidence for the structures of complexes 3c and 3d was provided by single-crystal X-ray crystallography. The in vitro inhibitory activity of the six Ag-NHC complexes was tested against trophozoites and cysts of the pathogenic Acanthamoeba castellanii strain and the efficacy sequence is as follows: 3d > 3c > 3f > 3a > 3b > 3e. At a concentration of 100 mu M in complexes 3c, 3d and 3f and after 72 h of incubation, 5.3, 3.2 and 6.3% A. castellanii trophozoite viabilities were observed, respectively. The utilization of elevated silver(I) drug concentrations, 1000 mu M, resulted in the near-total eradication of pathogenic protozoa.