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    Clinicopathologic features of obese patients with rectal cancer and short-term results of surgery
    (2018) Oter, Volkan; Ofkeli, Ozcem; Ulas, Murat; Ozer, Ilter; Bostanci, Erdal Birol
    Aim: Some authors related the increased body mass index (BMI) with postoperative complication rates also increase, number of harvested lymph nodes reduce and sparing the anal sphincter is much more challenging in the surgical management of rectal cancer. In this study, we evaluated clinic-pathologic features and short-term surgical results in obese and non-obese patients with rectal cancer. Material and Methods: 54 obese and 326 non-obese patients are evaluated for clinic-pathological features, postoperative complications, re-operation rates and mortality rates. Results: The rate of distally located rectal tumor is found significantly higher in obese patients than non-obese patients (p<0.05). Although anterior resection has been performed more commonly in Group-I, abdominoperineal resection procedure is found significantly higher in Group-II, (p<0.05)..Harvested lymph nodes ratio between two groups was quite close to each other so this difference is not statistically significant. .Postoperative results were similar between the groups except total postoperative complications and re-operations for anastomotic leak. Although re-operation rates for anastomotic leak are found different, they are quite close between the two groups and this difference is not statistically significant. In contrast to some of the previously published articles, there was not any significant difference in morbidity and mortality between the two groups in our study. Conclusion: In our opinion there is not a clear conclusion to change the operative strategy for enough number of harvested lymph nodes but meticulous technique should be utilized to reduce the rate of anastomotic leak and resultant re-operations in this group of patients
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    The effective factors on our early and late results, recurrence and survival in differential thyroid cancers: “An analysis of 184 patients”
    (2019) Bulut, Aziz; Ofkeli, Ozcem; Gozalan, Ahmet Ugur; Daglar Ozdemir, Gul; Doganay, Mutlu; Kama, Nuri Aydin
    Aim: The purpose of the study was to investigate the effective prognostic factors on recurrence and mortality in patients with differential thyroid cancer. Material and Methods: The effects of various parameters of demographic characteristics, the admission symptoms, physical examination, laboratory findings, pathological examination, and surgical method of 184 patients, who underwent surgery due to differential thyroid cancer between January 1986 and December 2009 in 4th General Surgical Clinic of Ankara Numune Training and Research Hospital, on prognosis were examined. The information of the patients was obtained from automation system of the hospital and Thyroid Cancer Information and Follow-Up Form of 4th General Surgical Clinic of Ankara Numune Training and Research Hospital.Results: The sample group consisted of 172 papillary cancer patients and 12 follicular cancer patients. The mean age of the patients was 45.4 years (15-78). There were 159 (86.4%) female patients and 25 (13.6%) male patients. The mean follow-up period of 161 (87.5%) patients, who were followed up regularly, was 73.26 months (1-231). The mean recurrence period was 77.66 months (1-150). Mortality was observed in eight (4.3%) patients during their follow-up period. The mean life expectancy of those who died was 66.87 months (1-150 months).* Single variable analysis revealed that the T stage and pathologic final stage were effective on recurrence. Painful nodules and palpable lymph nodes in the neck and the papillary histological malignant subtype variant, as well as the presence of vascular and adjacent organ invasion, multicentricity, T stage, the lymph nodes, distant metastasis, and the clinical stage during the admission were identified to be effective on mortality.Conclusion: The risk of recurrence is high in DTC patients with high T stage and advanced pathologic stage. The rate of survival of those with multicentric tumors and advanced pathologic stage is low. Therefore, it is important for patients to be followed up closely within a postoperative multidisciplinary context.Keywords: Differential; thyroid; cancer; recurrence; mortality.