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Öğe Carotid intima-media thickness in chronic obstructive pulmonary disease and survival: A multicenter prospective study(Wiley, 2019) Gulbas, Gazi; Turan, Onur; Sarioglu, Nurhan; Diken, Ozlem Ercen; Ogan, Nalan; Kadioglu, Esra Ekbic; Kurtipek, ErcanIntroduction Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality. Carotid intima-media thickness (CIMT) is a noninvasive method assessing atherosclerosis. Objective It was aimed to determine relationship and survival between COPD and CIMT. Methods CIMT was measured using Doppler ultrasound (USG) in 668 stable COPD patients at 24 centers. Patients were followed-up for 2 years. Results There were 610 patients who completed the study. There were 200 patients CIMT with <0.78 mm (group 1), and 410 with CIMT >= 0.78 mm (group 2). There was a significant difference at the parameters of age, gender, smoking load, biomass exposure, GOLD groups and degree of airway obstruction (FEV1) between groups 1 and 2. Our results revealed positive correlations between mean CIMT and age, smoking load (pack-years), biomass exposure (years), exacerbation rate (last year), duration of hypertension (years) and cholesterol level; negative correlations between CIMT and FEV1 (P < 0.05). According to logistic regression model, compared with group A, risk of CIMT increase was 2.2-fold in group B, 9.7-fold in group C and 4.4-fold in group D (P < 0.05). Risk of CIMT increase was also related with cholesterol level (P < 0.05). Compared with infrequent exacerbation, it was 2.8-fold in the patients with frequent exacerbation (P < 0.05). The mean survival time was slightly higher in group 1, but not significant (23.9 vs 21.8 months) (P > 0.05). Conclusion This study is the first regarding CIMT with combined GOLD assessment groups. It has revealed important findings supporting the increase in atherosclerosis risk in COPD patients. We recommend Doppler USG of the carotid artery in COPD patients at severe stages.Öğe Disease history of patients with COPD(Kare Publ, 2022) Suerdem, Mecit; Sanoglu, Nurhan; Ogan, Nalan; Arslan, Sertac; Yildirim, Guifem; Diken, Oziem Ercen; Bozkus, FulsenBACKGROUND AND AIM: This study aimed to obtain real-life data of patients diagnosed with chronic obstructive pulmonary disease (COPD) at least one year ago, including smoking history, inhaler device training, and the number of exacerbations. METHODS: This study was planned as a nationwide, prospective, observational, multicenter, and noninterventional study, and web-based electronic case forms were used to register the patients. RESULTS: A total of 460 patients from 11 centers were included, of whom 88.3% were males. Of the total patients, 137 (29.8%) were current smokers, and 292 (63.5%) were ex-smokers. One hundred twenty-four (29.6%) patients did not receive inhaler device training. Repeated inhaler device training in the follow-up visits was not performed in 255 (60.8%) patients. Of the total participants, 187 (41.0%) reported no exacerbations in the previous year. The mean number of exacerbations per person over the previous year was 1.19. The annual rates of influenza and pneumococcal vaccines were 34.8% and 4.2%, respectively. CONCLUSIONS: Patients should be trained more efficiently in the risks of COPD, use of inhaler devices, exacerbations, and improving quality of life.Öğe Pulmonary physician consultancy in emergency services in Turkey (PUPCEST) - a prospective multicenter study(European Respiratory Soc Journals Ltd, 2018) Diken, Ozlem Ercen; Ekici, Aydanur; Bektas, Hayriye; Yildiz, Hanifi; Tabaru, Ali; Ogan, Nalan; Gulhan, Pinar Yildiz[Abstract Not Available]