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Öğe Comparison of pulmonary function testing among non-smokers, hand-rolled cigarette smokers and factory made cigarette smokers(SEAMEO TROPMED Network, 2018) Turgut K.; Turtay M.G.; Kılıc T.; Oguzturk H.; Gulactı U.; Gur A.; Guven T.Tobacco use causes significant health problems. The aim of this study was to compare the following factors among factory-made cigarette (FMC) smokers, hand-rolled cigarette (HRC) smokers and non-smokers (NS): demographic characteristics, pulmonary function testing (PFT) and carboxyhemoglobin (COHb) levels. PFT included checking: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC, forced expiratory flow from 25-75% of the vital capacity (FEF25-75) and peak expiratory flow (PEF). We wanted to determine the impact of smoking on pulmonary function testing and to determine any differences in PFTs and COHb levels between FMC and HRC smokers. A total of 182 participants (all males) were included in the study. The subjects in the study were randomly chosen from emergency service admissions which had complaints other than respiratory system. The mean age of study subjects was 40.8 (range: 22-92) years. Mean age of starting smoking among HRC smokers was not significantly different from FMC smokers (95% CI:-0.55-2.37, p=0.220). HRC smokers had significantly lower economic and education levels than FMC smokers (95% CI: 9.0-45.2, p<0.01). NS had highest economic and educational levels (95% CI: 35.9-66.6, p<0.01) of the 3 study groups. The mean [±standard deviation(SD)] FEV1/FVC was 76.66 (±7.45) among FMC smokers (95% CI: 74.82-78.51), 77.36 (±8.14) among HRC smokers (95% CI: 75.36-79.36) and 83.13 (±5.08) among NS (95% CI: 81.70-84.56, p<0.01). The mean (±SD) FEV1 was 84.50 (±17.80) among FMC smokers (95% CI: 80.12-88.92 ), 89.4 (±15.8) among HRC smokers (95% CI: 85.56-93.32) and 95.30 (±13.3) among NS (95% CI: 91.59-99.07, p<0.01). The mean (±SD) PEF was 81.90 (±19.30) among HRC smokers (95% CI: 77.19-86.69), 78.10 (±18.70) among FMC smokers (95% CI: 73.47-82.74) and 86.20 (±16.0) among NS (95% CI: 81.70-90.69, p=0.06). The mean FVC, FEV1, FEV1/FVC, FEF25-75%, and PEF values among NS were significantly (p<0.05) higher for each variable than the mean of these values among FMC and HRC smokers. The mean COHb level among NS was significantly (p<0.05) lower than the mean COHb levels in the two smoking groups. There were no significant differences in PFT results or COHb levels between the two smoking groups (p>0.05). Cigarette smoking cause impairment of pulmonary function equally independent of the cigarette type (FMC, HRC) smoked. © 2018, SEAMEO TROPMED Network. All rights reserved.Öğe Complete atrioventricular block caused by mad honey intoxication.(2012) Oguzturk H.; Ciftci O.; Turtay M.G.; Yumrutepe S.The honey produced by the bees fed on Rhododendron family plants containing grayanotoxin is known as mad honey in our country. This intoxication is seen rarely. However, it may lead life-threatening hemoinstability mentioned above and may be confused with various diseases. For these reasons the exact diagnosis and treatment of this intoxication seems very important. We aim to describe a case admitted to the Emergency Department in consequence of mad honey intoxication and treated and discharged after hypotension and complete atrioventricular block development.Öğe Does 3-G mobile phone radiofrequency affect oxidative stress, sperm characteristics and testis histology?(2011) Oguzturk H.; Beytur A.; Ciftci O.; Turtay M.G.; Samdanci E.; Dilek O.F.This study aims to investigate the effects of electromagnetic radiation (EMR) delivered by mobile phones on oxidative stress, histological damage and sperm characteristic in rats. For this purpose, 18 male rats (9 in the study group and 9 in the control group) were used. The rats in experimental group were exposed to EMR from an active (1.9-2.2 GHz) mobile phone (MP) for 20 min per day for 20 days. The rats in control group were exposed to an MP without a battery for the same period. The results showed that there was no significant differences in oxidative stress parameters (TBARS, GSH, SOD, CAT, GSH-Px), testis histology and reproductive organ weight (testis, epididymis, prostate weight) between the control and the study groups. On the other hand, it was observed that the use of MPs may have negative effects on the sperm characteristics (especially sperm motility) in rats. In conclusion, it was suggested that the exposure of EMR caused a decrease of fertility capacity due to their effects on sperm characteristics. © by PSP.Öğe The effect of chronic carbon monoxide exposure on brain in Barbecue workers(Parlar Scientific Publications, 2014) Turtay M.G.; Yumrutepe S.; Kahraman A.S.; Bentli R.; Oguzturk H.; Firat C.; CoIak C.The aim of our study is to investigate whether chronic carbon monoxide (CO) exposure has effects on the brains of the people who work as barbecue workers (BWs) for a long time. Twenty males who had been working in the indoor environments of various restaurants (Group 1) and 20 healthy males who were matched by age with the other group (Group 2) were included in the study. Laboratory tests were performed in both groups of people. Magnetic Resonance Spectroscopy (MRS) was applied to the people whose blood samples were taken. In Group 1, significant correlations were not detected between carboxyhemoglobin (COHb) values and the variables of age, working hours, hemoglobin (Hb), white blood cell (WBC), hematocrit (HCT), platelet (PLT), mean platelet volume (MPV), pH, oxygen saturation (Sat 02) (p> 0.05). In terms of Hb, WBC, HCT, PLT, MPV, pH, Sat 02, COHb, N-acetylaspartate/creatine in basal ganglion, choline/creatine in basal ganglion, N-acetylaspartate/creatine in frontal lobe periventricular white matter, choline/creatine in frontal lobe periventricular white matter variables, significant differences between Group 1 and Group 2 were not determined. (p>0.05). As a result of this study; it is detected that chronic exposure to CO in BWs does not have any effects on brain with respect to MRS imaging method.Öğe Lycopene prevents experimental priapism against oxidative and nitrosative damage(Verduci Editore, 2014) Ciftci O.; Oguz F.; Beytur A.; Polat F.; Altintas R.; Oguzturk H.OBJECTIVE: Priapism is a persistent and often painful penile erection in the absence of sexual stimulation. It can cause progressive fibrosis, edema and drying of the erectile tissue and then it can lead to erectile dysfunction. Previous studies suggested that, neu-ronal nitric oxide levels increased during the pri-apism. High NO levels can result in the formation of reactive oxygen species (ROS) leading to oxidative stress in tissue and reproductive system. The aim of this study was to evaluate oxida-tive and nitrosative effects caused by priapism in cavernosal tissue and serum, and determinate beneficial effects of lycopene on ischemic pri-apism. MATERIALS AND METHODS: 32 rats were randomly divided into four groups and the first group being as the control. In the second group, experimental ischemic priapism was formed for an hour and then 1hour reperfusion was provided. In the third group, lycopene was intraperi-toneally given at the dose of 10 mg/kg. In the fourth group, lycopene were administered to rats with experimental priapism. RESULTS: Priapism caused a significant increase in TBARS (thiobarbituric acid reactive substances) and NO levels and a significant decrease in the levels of GSH, CAT, GPx and SOD in serum and cavernosal tissue of rats. However, lycopene significantly increased GSH, CAT, GPx and SOD levels but decreased formation of TBARS production and NO in rats with priapism. CONCLUSIONS: Our findings indicated that is-chemic priapism lead to significant oxidative and nitrosative damage in cavernosal tissue and serum samples of rats. However lycopene treatment eliminates these negative effects induced by priapism. For this reason, we suggested that lycopene may be used in the treatment of pri-apism.Öğe Mushrooms: The velvety poison(A. CARBONE Editore, 2015) Gürbüz S.; Oguzturk H.; Turgut K.; Turtay M.G.; Guven T.Introduction: Mushroom poisoning, a frequent health condition worldwide, documented since ancient times, can occur when an amateur mushroom hunter misidentifies a mushroom due to the close resemblance between toxic and edible species. In the majority of cases, mistakenly ingested mushrooms cause only gastrointestinal irritation, but certain toxic species, such as Amanita phalloides, can cause multiorgan failure and death. This study investigated the demographic and clinical characteristics of 79 mushroom poisoning cases, together with the treatments applied and their outcomes. Materials and methods: A total of 79 adult patients who were admitted to the emergency ward of the medical faculty of Inönü University between 2011 and 2014 were evaluated retrospectively. Results: The 79 patients ranged in age from 18 to 85 years; 44 (55.7%) were female and 35 (44.3%) were male. A total of 62 (78.4%) of the poisoning cases occurred during the spring and autumn seasons, which in Turkey are characterized by the highest levels of rainfall. At admission, nausea was observed in 76 (96.2%) cases, vomiting in 63 (79.7%), abdominal pain in 18 (22.8%), and diarrhea in 3 (3.8%). In 35 (44.3%) cases, toxicity symptoms onset within 6 hours of ingestion and later in 45 (64.5%) patients. A total of 73 patients recovered fully following medical treatment and were therefore discharged; three others received a liver transplant, one of whom survived. The remaining three patients, in whom no transplantations were performed, died; therefore a total of five patients did not survive. Conclusion: Mushroom poisoning can cause serious, potentially fatal illness. Rapid toxin analysis, prompt treatment and liver transplantation decrease the likelihood of mortality.
