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    Increasing the Functionality of Surgical Masks with Water-Soluble Antibacterial Polymers and MTT Test Studies
    (Springernature, 2024) Oktay, Aysenur Cakmak; Demirci, Sevilay; Tanriverdi, Aslihan Aycan; Kurucay, Ali; Ata, Ahmet Cagri
    Herein, reversible addition-fragmentation chain transfer (RAFT) agent salts containing water-soluble, antibacterial macro xanthate polyethylene glycol (PEG) were synthesized. Macro xanthate RAFT agent salts were featured by proton nuclear magnetic resonance (1H-NMR) spectroscopy and Fourier transform infrared (FT-IR) spectroscopy. PEG1500 Macro Xanthate RAFT agent pure water and PEG400 Macro Xanthate RAFT pure water solutions were applied to surgical masks by spraying. Moreover, these polymers were used to determine the minimum inhibitory concentration (MIC) on standard bacterial strains of Gram-positive bacteria and Gram-negative bacteria in the modified Broth MicroDilution method. It was determined that the synthesized polymers prevented the growth of bacteria. Mus musculus mouse fibroblast cells (L-929) were used in the cytotoxicity test of the materials performed by the direct method. It was determined by the Cytotoxicity 3-4,5-dimethyl-thiazolyl-2,5-diphenyltetrazolium bromide (MTT) test that these polymers were not harmful to human health. The biocompatibility of Macro xanthate RAFT agent salts was above 80%.