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Öğe The alarm and action levels of waist circumference in overweight and obese Turkish women(Elsevier Sci Ltd, 2007) Tanyolac, Sinan; Cikim, Ayse Sertkaya; Azezli, Adil Dogan; Orhan, YusufObjective: To determine alarm and action levels' of waist circumference (WC) in overweight and obese Turkish women and investigate the relationship with cardiovascular risk factors. Research subjects and methods: Four thousand three hundred and seventy-five women aged 18-81 years selected from Istanbul Faculty of Medicine Obesity outpatient clinic. WC, waist-to-hip ratio (WHR), body mass index [(BMI) (weight (kg)/height (m(2)))], blood pressure, and biochemical parameters were analyzed. Results: There was strong correlation between BMI and WC levels (r: 0.852). The regression equation which describes this correlation [WC=1.68 x BMI (kg/m(2)) + 39.2 +/- 1.6] was applied to 500 random samples in order to define alarm and action levels for WC. Our results indicated that alarm level of WC at BMI 25 kg/m(2) is 81 cm and action level of WC at BMI 30kg/m(2) is 90cm. Validating samples were divided into three groups: group I (WC levels below 81 cm, n: 421), group 11 (WC levels between 81 and 90cm, n: 718), group III (WC Levels above 90cm, n: 2736) and further correlative analyses were performed. Strong differences within alarm and action groups in terms of cardiovascular risk factors were identified. The prevalence and mean values of cardiovascular risk factors significantly increased with WC. In group 1 one or more risk factor prevalence was 64.8%, whereas in groups 2 and 3 prevalence was increased to 76.8 and 89%, respectively. Conclusion: Turkish women with WC greater than 81 cm should gain no further weight and those greater than 90cm should reduce their weight. (c) 2007 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.Öğe Correlation between educational status and cardiovascular risk factors in an overweight and obese Turkish female population(Aves, 2008) Tanyolac, Sinan; Cikim, Ayse Sertkaya; Azezli, Adil Dogan; Orhan, YusufObjective: The prevalence of obesity is rapidly increasing in Turkey as well as all over the world. Educational inequalities play an important role in the development of obesity. In this study, our aim is to evaluate how educational status affects obesity and cardiovascular risk factors in the overweight and obese Turkish female population. Methods: In this study, 3080 overweight (n=633) and obese (n=2447) Turkish women who applied to Istanbul Faculty of Medicine Obesity Outpatient Clinic were evaluated retrospectively. Educational status was classified according to the subjects' latest term of education. Subjects were evaluated in terms of anthropometric and biochemical parameters. The association of educational level with cardiovascular risk factors and metabolic syndrome were analyzed using logistic regression analysis. Results: Educational levels after adjusted continuous variables (age and body mass index) showed significant correlation with waist circumference, total and high-density lipoprotein cholesterol, triglycerides, low-density lipoprotein cholesterol and glucose. Low educated class (LEC) had a 1.93 (95% CI - 1.56-2.39, p=0.001) fold increased risk than high educated subjects for cardiovascular risk factors. Metabolic syndrome prevalence was more prevalent and significant risk increase was observed in LEC (OR = 2.02, 95% CI -1.53-2.67, p=0.001). Conclusions: Low educational status is a contributing factor for development of obesity and increased risk for obesity related disorders in the Turkish overweight and obese female population. Population based information and educational policies might prevent obesity related disorders and decrease cardiovascular mortality. (Anadolu Kardiyol Derg 2008; 8: 336-41)Öğe Fazla kilolu ve şişman kadınlarda boy uzunluğunun risk göstergeleri ile ilişkisi(2005) Akkaya, Vakur; Çıkım Sertkaya, Ayşe; Özbey, Neşe; Orhan, YusufÖz: Amaç: Kısa boy bazı kardiyovasküler risk faktörleri ile ilişki göstermektedir. Bu çalışma fazla kilolu ve şişman kadınlarda boy uzunluğu ile çeşitli kardiyovasküler risk faktörleri arasındaki ilişkiyi araştırmak amacıyla gerçekleştirildi. Gereç ve yöntem: Beden kitle indeksi 25-67 kg/m2 arasında değişen 3665 fazla kilolu ve şişman kadında boy ile serum glukoz, ürik asit, total ve HDL-kolesterol, trigliserit, insülin, HOMA (homeostasis model assessment), sistolik ve diyastolik damar basıncı arasındaki ilişki, korelasyon analizi ve boy uzunluğuna göre ayrılmış dört grupta ANOVA, eşlenmemiş seri t-testi ve ki-kare testi ile araştırıldı. Bulgular: Olgularda boy uzunluğu ile ağırlık ve HDL kolesterol arasında anlamlı pozitif, boy uzunluğu ile yaş, beden kitle indeksi, glukoz, kolesterol, trigliserit, maksimum ve minimum damar basıncı ve bel-kalça oranı arasında anlamlı negatif ilişkiler bulundu. Boy ile ürik asit, insülin ve HOMA arasında anlamlı bir ilişki saptanmadı. Boy uzunluğuna göre dört gruba ayrılan olgularda ANOVA ile yaş, ağırlık, beden kitle indeksi, glukoz, maksimum ve minimum damar basıncı, kolesterol, trigliserit ve bel kalça oranı açısından gruplararası anlamlı farklar bulundu. Vakalarda çeyrek gruplar arasında diabetes mellitus, hipertansiyon, hiperkolesterolemi ve abdominal şişmanlık varlığı bakımından anlamlı farklılık bulundu. Aksine hipertrigliseridemi ve HDL-kolesterol düşüklüğü varlığı açısından anlamlı bir fark saptanmadı. Sonuç: Bulgularımız, fazla kilolu ve şişman kadınlarda kısa boyun hiperglisemi, hipertansiyon ve hiperkolesterolemi gibi tablolar birlikte olabileceğini desteklemektedir. Bu nedenle kısa boylu ve fazla kilolu veya şişman olan kadınlar kardiyovasküler risk varlığı bakımından daha yakından izlenmelidir.Öğe THE RELATIONSHIP BETWEEN HEIGHT MEASUREMENT AND METABOLIC RISK MARKERS IN OVERWEIGHT AND OBESE WOMEN(Istanbul Univ, Faculty Medicine, Publishing Office, 2005) Akkaya, Vakur; Sertkaya, Ayse Cikim; Ozbey, Nese; Orhan, YusufObjective: The aim of this study was to determine the relationship between height and cardiovascular risk markers in overweight and obese women. Materials and methods: The study group was composed of 3665 overweight or obese women with body mass index varying from 25 to 67 kg/m(2). In order to determine the relationship between body height and various cardiovascular risk markers, ANOVA, unpaired-t test and chi-square tests were performed. Results: Data analyses indicated a significant positive relationship between height and weight and HDL cholesterol and an inverse relationship between height and age, serum total cholesterol, glucose, triglyceride, systolic and diastolic blood pressure. No significant relationship was found between height and uric acid, insulin and HOMA (homeostasis model assessment). Age, weight, body mass index, glucose, cholesterol, triglyceride, systolic and diastolic blood pressures were found to vary between quartiles of stature. The incidence of diabetes mellitus, hypertension, hypercholesterolemia and abdominal obesity also was found to differ significantly between quartiles of stature using ANOVAanalysis. Conclusion: These results support the suggestion that short stature may be relevant to hyperglycemia, hypertension and hypercholesterolemia. Therefore, the measurement of metabolic risk markers could be useful in clinical screening for overweight and obese women of short stature.Öğe Türk kadınlarında boyun çevresi ile vücut yağ miktarı arasındaki ilişki(İstanbul Üniversitesi İstanbul Tıp Fakültesi Mecmuası, 2004) Sertkaya, Ayşe Çakım; Akkaya, Vakur; Özbey, Neşe; Orhan, YusufÖz: Çeşitli vücut ağırlıklı kadınlarda boyun çevresi (neck circumference, NC) ölçümü ile beden kitle indeksi (body mass index, BMI) arasındaki ilişkiyi araştırmak amacıyla gerçekleştirildi. BMI düzeyi 14-58 kg/m2 arasında değişen 1861 kadında 25 ve 30 kg/m2 BMI değeri ile NC arasındaki ilişki "receiver output curve" (ROC) analizi ile araştırıldı. Tüm vakalarda NC ile BMI arasında anlamlı bir ilişki saptandı (r: 0.6998, p < 0.001). ROC analizi ise BMI >= 25.0 ve >= 30.0 kg/m2 düzeylerine uyan en iyi NC cutoff değerleri sırasıyla 32 ve 35 cm bulundu. Bulgularımız, boyun çevresinin fazla kilolu ve şişman Türk kadınlarını belirlemede yardımcı basit bir ölçüm olabileceğini desteklemektedir. NC düzeyi 32 cm'den yüksek olanlar fazla kilolu ve 35 cm'den yüksek olan kadınlar şişman olarak tanımlanabilir.
