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Öğe Assessment of ganglion cell complex, macular thickness, and optic disc parameters in keratoconus patients(Wolters Kluwer Medknow Publications, 2020) Orman, Gozde; Firat, Penpe Gul; Doganay, Selim; Doganay, DeryaPURPOSE: Keratoconus (KC) is bilateral noninflammatory corneal disorder characterized by progressive corneal thinning, protrusion, and scarring. The purpose of this study was to evaluate ganglion cell complex(GCC), macula thickness(MT) and optic head disc parameters in keratoconus patients. METHODS: A hospital based prospective clinical case series was performed in Inonu University School of Medicine. 52 eyes of 52 keratoconus patients and 50 eyes of 50 normal patients were enrolled. RESULTS: There is no statistically significant in MT between groups. GCC in nasal superior, temporal superior and temporal inferior 9 mm from macula were found statistically significant decrease in keratoconus group (p<0,05). In optic disc analysis fifth and the eleventh clock-hour quadrants of peripapiller retina nerve fiber layer and cup area ratio were found statistically significant decrease in keratoconic eyes (p<0,05). CONCLUSION: We thought that structural retinal changes seem in keratoconus eyes; keratoconus pathogenesis may affect not only cornea but also retina and optic nerve head.Öğe Endoscopic Transcanalicular Diode Laser Dacryocystorhinostomy: Is It an Alternative Method to Conventional External Dacryocystorhinostomy?(Lippincott Williams & Wilkins, 2013) Derya, Kutukde; Demirel, Soner; Doganay, Selim; Orman, Gozde; Cumurcu, Tongabay; Gunduz, AbuzerPurpose: To compare the success rates of endoscopic transcanalicular diode laser dacryocystorhinostomy (EL-DCR) and external DCR. Materials and Methods: Operations were performed on 55 eyes of 54 patients who had distal nasolacrimal canal obstruction. External DCR was performed on 29 of the eyes and EL-DCR on 26 of them. Success was defined based on subjective relief of patients reported at their final examinations. Results: There were 23 women and 6 men in group 1 and 19 women and 6 men in group 2 (p = 0.77). The mean ages of groups were 45.24 +/- 12.08 (range, 15-74) and 43.2 +/- 17.01 (range, 11-72) years, respectively (p = 0.63). The mean follow-up times were 8.82 +/- 5.51 (range, 3-18) and 7.12 +/- 2.96 (range, 2-12) months, respectively in groups (p = 0.58). The success rates based on symptoms were measured at 25 of 29 (86%) and 17 of 25 (68%) for 2 groups. The difference in the success rates was higher but not found to be statistically significant (p = 0.202). The authors found various conditions related to nasal passage in 4 of 8 unsuccessful EL-DCR, including allergic rhinitis, nasal crust, silicone tube reaction, and unsuitable passage for endoscopic surgery. Conclusions: The success rate of EL-DCR was lower than that of the external DCR; however, no statistically significant difference was observed. Endoscopic transcanalicular diode laser DCR may be considered as an alternative method to external DCR with these results. (Ophthal Plast Reconstr Surg 2013;29:15-17)Öğe Evaluation of Antimicrobial Activities of Topical Anesthetics(Ortadogu Ad Pres & Publ Co, 2011) Orman, Gozde; Cankaya, Cem; Doganay, Selim; Gunal, Selami; Otlu, BarisObjective: To investigate the antimicrobial activities of the drugs used as topical anesthetics. Material and Methods: Test drugs (oxybuprocaine 0.4%, proparacaine hydrochloride 0.5%, lidocaine 10%) were tested for Staphylococcus aureus (S. aureus) ATCC 29213, Streptococcus pneumoniae (S. pneumoniae)ATCC 27336, Pseudomonas aeruginosa (P. aeruginosa) ATCC 27853, standard strains of Escherichia coli (E. coli) ATCC 25922 and Candida albicans (C. albicans) using modified microplate alamar blue method (MABA) in different concentrations according to Clinical and Laboratory Standards Institute (CLSI) criteria. Results: S. Pneumoniae proliferated in none of the dilutions of three topical anesthetics. S. aureus proliferated in all dilutions of oxybuprocaine and lidocaine and in no dilutions of proparacaine hydrochloride. P. Aeruginosa proliferated in 0.2% dilution of oxybuprocaine and 2.5% and 5% dilutions of lidocaine and in all dilutions of proparacaine hydrochloride. C. albicans proliferated in 0.05% and 0.025 % dilutions of oxybuprocaine, 1.25% and 0.625% dilutions of lidocaine, 0.125%, 0.0625% and 0.0312% dilutions of proparacaine hydrochloride. E. Coll proliferated in all dilutions of oxybuprocaine, 0.625% dilutions of lidocaine and 0.125%, 0.0625% and 0.0312% dilutions of proparacaine hydrochloride. Conclusio: Topical anesthetics that are used before sample collection in superficial ocular infections can cause false results in cultures by inhibating proliferations of microorganisms. Thus, it is important to know the effects of topical anesthetics and dilutions on bacterial proliferation.Öğe Influence of corneal parameters in keratoconus on IOP readings obtained with different tonometers(Taylor & Francis Ltd, 2013) Firat, Penpe Gul; Orman, Gozde; Doganay, Selim; Demirel, SonerBackground Accurate intraocular pressure (IOP) measurement is important but of unsure reliability in patients with keratoconus. Different types and models of tonometers are available. This study investigated the influence of corneal parameters on IOP readings obtained by a Goldmann applanation tonometer, a non-contact tonometer and a dynamic contour tonometer. Methods IOP readings with the Goldmann applanation, non-contact and dynamic contour tonometers were obtained from 52 patients with keratoconus and from 50 normal subjects and their corneal parameters were measured using a Pentacam. Results The mean IOP measurements in keratoconus obtained with the Goldmann applanation, non-contact and dynamic contour tonometers were statistically significantly different from the mean IOP measurements in the normal subjects (p < 0.0001; p < 0.005; p < 0.0001, respectively). In the keratoconus group, the thinnest corneal thickness (TCT), steepest keratometry, the corneal curvature (CC), central corneal thickness (CCT) and the posterior corneal curvature (PCC) had a significant effect on the Goldmann applanation and non-contact tonometers but not on the dynamic contour tonometer. In the control group, thinnest and central corneal thicknesses had a significant effect on findings with the Goldmann and non-contact tonometers but not on the dynamic contour tonometer. The corneal volume (CV) had no significant effect on the three tonometers in both groups. Conclusions The corneal parameters affecting the IOP readings of the Goldmann applanation tonometers, non-contact tonometers and the dynamic contour tonometers are not the same. While the Goldmann applanation and non-contact tonometers were significantly affected by the corneal parameters that were measured, the dynamic contour tonometer was not affected by any of these corneal parameters.Öğe Ocular Surface Rreconstruction with Allogeneic Limbal Stem Cell and Autologous Oral Mucosal Graft: Two Cases(Turkish Ophthalmological Soc, 2013) Orman, Gozde; Demircl, Soner; Doganay, Selim; Duman, Behicc Suheda; Kutukde, DeryaTwo patients with severe ocular surface damage in both eyes are presented. In the patient with limbal stem cell deficiency, allogeneic limbal stern cell transplantation was performed. In the other patient with recurrent pterygium and symblepharon, autogenic oral mucosa transplantation was performed to manage the symblepharon. In this study, we discuss the methods that can be performed for reconstruction in patients with ocular surface disorder in both eyes.Öğe Reply re: Endoscopic Transcanalicular Diode Laser Dacryocystorhinostomy. Is It an Alternative Method to Conventional External Dacryocystorhinostomy?(Lippincott Williams & Wilkins, 2013) Demirel, Soner; Derya, Kutukde; Doganay, Selim; Orman, Gozde; Cumurcu, Tongabay; Gunduz, Abuzer[Abstract Not Available]
