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Öğe Estimating body weight from foot measurements in the Eastern Turkish Population using linear methods and artificial neural networks(2024) Oruç, Mucahit; Celbiş, Osman; Parlak, Muhammed Emin; Turan, Ömer; Özkul, Bengü BerrakIn forensic and archaeological contexts, accurately determining an individual's age, sex, height, and weight is essential for the identification of unidentified bodies and dismembered remains. This study assesses the effectiveness of linear regression analysis and artificial neural networks (ANNs) in estimating body weight using foot measurements within the Eastern Turkish population. The research was conducted with medical students, including 149 volunteers—76 males and 73 females. Participants' height and weight were recorded using a stadiometer. Foot measurements were taken with a Vernier caliper and an osteometric board. The data were assessed utilizing SPSS 26.0, and ANN models were developed using the Keras library within the Google Colab platform. In terms of height, weight, and foot size, all these values were significantly higher in males than in females. Linear regression methods resulted in a root mean squared error (RMSE) of 11.83 kg for males, 6.23 kg for females, and 9.56 kg for the entire sample. With ANNs, these error values were reduced to 10.13 kg for males, 5.10 kg for females, and 8.07 kg for the entire sample. The analysis shows that ANNs are more adept at handling complex data, leading to improved prediction accuracy.Öğe Evaluation of Thoracic Region Complications Associated with Cardiopulmonary Resuscitation Applied to Cases of Fall From Height(2023) Altın, İsmail; Dündar, Ahmet Sedat; Gümüşboğa, Erkal; Oruç, Mucahit; Celbiş, Osman; Şamdancı, EmineAim: The most common causes of blunt trauma are traffic accidents and falls from height. Thoracic region complications may be seen in cardiopulmonary resuscitation (CPR). The aim of this study was to examine thoracic complications developing in cases applied with CPR following a fall from height with no direct chest trauma. Materials and Methods: The thoracic complications of CPR were examined in cases with CPR applied after a fall from height following the exclusion of cases where death occurred and an autopsy was performed. Results: Evaluation was made of 109 cases who met the study criteria, comprising 82 males and 27 females. Fractures of the sternum and costa were seen at a higher rate than reported in studies in literature. No statistically significant difference was determined between the genders in respect of fracture rates. As age increased, there was found to be a statistically significant increase in fractures. Conclusion: This is the first study to have examined CPR complications following a fall from height. Just as there are direct effects of trauma on the body in general, there are also known to be some indirect effects. The results of this study showed an in increase in thoracic region complications developing after CPR applied to cases who developed cardiac arrest following a fall from height.Öğe Karbondioksit ve Karbonmonoksite Maruz Bırakılan Sıçanlarda Biyokimyasal ve Moleküler Genetik Parametrelerin Değişimi(2016) Celbiş, Osman; Çifçi, Osman; Doğan, Mustafa; Oruç, MucahitKarbondioksit ve Karbonmonoksite Maruz Bırakılan Sıçanlarda Biyokimyasal ve Moleküler Genetik Parametrelerin Değişimi Karbonmonoksit (CO) zehirlenmesi beyin, kalp, böbrek, iskelet kası, deri, periferal sinir gibi hemen hemen bütün organları etkiler. Ülkemiz dâhil gelişmiş ve gelişmekte olan ülkelerde, özellikle kış aylarında, karbonmonoksit zehirlenmelerine bağlı ölümler sıkça görüldüğü bildirilmektedir. Klinik olarak tanı ve tedavi takibinde karboksihemoglobin (CO-Hb) düzeyi kullanılmakla birlikte, oluşan toksisite durumunun her insanda farklılık göstermesi ve ağırlık derecesinin her zaman için COHb düzeyi ile kolere olmaması nedeniyle farklı mekanizmaların da toksisitede yer aldığı düşünülmektedir. Bu durumun açıklanması için yapılan çalışmalarda nöro-endokrin dokularda nöroprotektif rolü olduğu yönünde çalışmalar yapılan ve nöroglobin olarak isimlendirilen, nöronal dokuya özgü bir globin türevi 2000?li yılların başında tanımlanmıştır. Beyinde hasar nedniyle oluşan durumlarda, arsenik gibi nörotoksik ajanlara bağlı oluşan durumlarda nöroglobin sentezi ile ilgili çalışmalar yapılmıştır. Ancak; nöroglobin ile ilgili çalışmalarda oluşan hipoksik durumların nedenleri arasındaki farklılık olup olmadığı, Karbonmonoksit veya karbondioksite maruziyet neticesinde oluşabilecek durumların ve kann biyokimyasındaki değişikliğin sentez üzerinde etkisi hususunda literatür bilgisine rastlanmamıştır. Konu bu açıdan özgün bir değer taşımaktadır. Çalışmada ağırlıkları 300 gr (±50 gr) olan 36 adet Wistar-Albino cinsi erkek sıçan kullanıldı. Sıçanlar eşit olarak 3 gruba (n=12) ayrıldı. Hazırlanmış ve kontrolleri tamamlanmış deney ortamında; bir gruba 15 dk süreli CO2, diğer ruba 15 dk süreyle CO gazları verildi. Deney sonunda gruplardan kan gazı tetkiki, nöroglobin mRNA tetkiki ve oksidan/antioksidan kimyasal parametrelerin tetkiki açısından kan ve beyin dokulaı usuüne uygun olarak alındı. Çalışmada çıkan sonuçların karşılaştırılmsında CO ve CO2? ye maruz kalan gruplarda nöroglobin mRNA seviyesinde, kan ve beyin dokuya ait kimyasal parametrelerde ve kan gazı parametrelerinde değişimler olduğu görüldü. Çalışmamızın Adli Tıp Biliminde genotoksisite ve adli toksikoloji açısından yapılacak olan daha kapsamlı çalışmalara ışık tutacak ve literatüre farklı bir bakış açısı katacak bir çalışma olduğu kanaatindeyiz.Öğe Mitral papillary muscle rupture associated with blunt chest trauma and the effect of alcohol: A case report(2024) Oruç, Mucahit; Erdil, Nevzat; Celbiş, Osman; Yılmaz, MesutMitral regurgitation associated with papillary muscle rupture following blunt chest trauma is an extremely rarely seen pathology. The risk of myocardial injury is much higher than normal in blunt chest traumas that develop in people who have consumed high doses of alcohol. In this case article, we present our successful diagnosis and treatment approach in a 39-year-old patient who had high-dose alcohol intake and developed acute mitral regurgitation as a result of blunt chest trauma due to a traffic accident. It may be life-saving to keep in mind that there may be life-threatening myocardial injuries in patients with blunt thoracic trauma who have consumed alcohol.Öğe Otopsisi Yapılan ve Kanda Alkol, Uyutucu Uyuşturucu ve Uyarıcı Madde Tespit Edilen Olguların Retrospektif Olarak İncelenmesi(2025) Oruç, Mucahit; Samdanci, Emine; Nalçacı, Sultan; Güven, SalihAmaç: Adli Tıp Kurumu bir Grup Başkanlığında otopsisi yapılmış; toksikolojik incelemesinde alkol, uyutucu, uyuşturucu veya uyarıcı madde tespit edilen olguların retrospektif olarak değerlendirilmesi. Yöntemler: Ocak 2017 ile Aralık 2022 tarihleri arasında otopsisi gerçekleştirilen 2689 olgu retrospektif olarak incelendi. Tüm olgular içerisinde 251 olgunun kanında psikoaktif madde saptandı. Bu olgular; yaş, cinsiyet, ölüm nedenleri ve tespit edilen madde profilleri açısından değerlendirildi. Ayrıca esas ölüm nedeni uyutucu, uyuşturucu veya uyarıcı madde intoksikasyonu olarak belirlenen 9 olguda olay bilgisi, dış muayene ve histopatolojik inceleme sonuçları verildi. Bulgular: Otopsisi yapılan olguların %9,3’ünün (n=251) kanında psikoaktif madde tespit edildi. Bu 251 olgunun %91’i (n=229) erkek, %9’u (n=22) kadındı. Madde kullanımı kadınlarda en sık 31-40, erkeklerde ise 21-30 yaş grubunda görüldü. En yüksek madde tespit oranı %11 (n=27) ile temmuz ayında kaydedildi. Olguların %65,73’ünde (n=165) alkol, %2,78’inde (n=7) ise metanol saptandı. Alkol miktarı %9,26’sında (n=15) 250 mg/dL üstünde, metanol miktarı %3,63’ünde (n=6) 151 mg/dL üstünde bulundu. Erkeklerde en sık tespit edilen madde %18’lik (n=42) oranla amfetamin tipi uyarıcılar olup bu gruptaki yaş ortalaması 41,52 olarak hesaplandı. Madde kullanımı en çok %23 (n=58) ile ateşli silah yaralanmalarına bağlı ölümlerde gözlendi. Esas ölüm nedeni uyuşturucu veya uyarıcı madde intoksikasyonu olan olgularda çoklu madde kullanımı saptanmış olup en yüksek oran amfetamin türevi uyarıcılarda görüldü.Uyuşturucu madde intoksikasyonu sonucu evde ölü bulunan, 36 yaşındaki erkek bir olguda, 4361,76 ng/mL metamfetamin tespit edildi. Histopatolojik incelemede beyinde subaraknoidal taze kanama, karaciğerde ise makroveziküler steatoz saptandı. Sonuç: Madde kullanımının ölüm üzerindeki etkisi ancak yapılan analizlerle belirlenebilir. Maddelerin tespiti bu maddelerin temin edilmesinin ve yayılmasının önlenebilmesi için gerekli önlemlerin alınmasını gerektirir.Öğe Post-traumatic stress and secondary traumatic stress of earthquake-affected and non-affected healthcare workers after the 6th February Earthquake in Türkiye(Turkish Society of Public Health Specialists, 2025) Taş, Ayşe; Akpınar, Günseli; Yükseler, Abdullah; Oruç, Mucahit; Celbiş, OsmanObjective: This study aims to investigate the presence of post-traumatic stress disorder and secondary traumatic stress in earthquake-affected healthcare workers (HCW) and non-affected deployed health workers. Method: Healthcare professionals deployed to earthquake-affected areas from the provinces not affected by the earthquake were determined as the first group and healthcare personnel who have experienced the earthquake themselves were determined as the second group. Data was collected via a form to investigate sociodemographic information, occupational exposure, post-earthquake experience, Post-Traumatic Stress Disorder Symptom Self-Report Scale (PSS-SR), and Secondary Traumatic Stress Scale (STSS). Mann-Withney U test, Kruskal Wallis test, and chi-square test were used to evaluate the analytical relationship. Results: The median PSS-SR score of healthcare workers who were non experienced of the earthquake (14.0 (5.0-29.0)) was found to be lower than the median PSS-SR score (27.0 (16.0-34.0)) of healthcare workers who were affected by the earthquake (p<0.001). The median STSS score of healthcare workers who had non experienced the earthquake (30.0 (22.0-48.0)) was found to be lower than the median STSS score of the earthquake-affected healthcare workers (50.0 (38.0-58.0)) (p<0.001). The sleep patterns and nutrition patterns of the earthquake-affected healthcare personnel were more negatively affected than the non-affected healthcare personnel (p<0.001). Conclusion: The PSS-SR and STSS scores were higher and sleep patterns and nutrition were affected more after the earthquake than those who were non-earthquake victims. For this reason, in health workforce planning, it would be appropriate to continue services by deployed healthcare workers instead of disaster-affected healthcare workers and to provide psychological support to earthquake-affected healthcare workers. ©Copyright 2025 by the Association of Public Health Specialist (https://hasuder.org.tr) Turkish Journal of Public Health published by Cetus Publishing.Öğe Retrospective Analysis of Injuries Resulting from Traffic Accidents(2024) Oruç, Mucahit; Celbiş, Osman; Yılmaz, MesutAim: To evaluate injuries and organ damage occurring in traffic accidents, and the cause of death in cases with mortality. Material and Method: The study included cases involved in traffic accidents who presented at hospital in a 4-year period. The cases were evaluated in respect of age, gender, injuries, alcohol consumption, form of involvement in traffic, and cause of death in deceased cases. The data were analyzed using SPSS vn. 26.0 software. Results: The total 3039 cases included in the study comprised 68.08% males and 31.92% females. Of the cases who presented at hospital, 4.11% died. The age group most involved in accidents was the 20-29 years group. The bones most frequently fractured were the costae. According to body regions, the nasal bone was the bone most often fractured in the head region, the humerus in the upper extremities, the pubis in the pelvis, the tibia in the lower extremities, and the costae in the chest region. The abdominal organ most often damaged was the liver. Conclusion: A statistically significant correlation was determined between gender and fractures of the ischium, sacrum, iliac, and pubic bones, with these fractures seen more in females than males. This higher rate of pelvic fractures in females can be attributed to the differences in male and female pelvic anatomy.Öğe THE EFFECT OF DIFFERENT PROCESSING METHODS ON AMYGDALIN LEVELS AND SOME PHYSICOCHEMICAL PROPERTIES OF APRICOT KERNELS(Inonu University, 2025) Nalçaci, Sultan; Oruç, Mucahit; Şamdanci, EmineIn this study, the amygdalin content of the Hacıhaliloğlu, Kabaaşı, and Zerdali varieties was determined using an LS-MS/MS device. Methods to reduce the amygdalin content in raw bitter apricot kernels to a safe level for consumption were identified. To remove bitterness treatments such as alkaline treatment with sodium bicarbonate (4-10% NaHCO3, 7-15 min), ultrasound (30-50 °C, 30-60 min), microwave (240-560 W, 2-5 min) and roasting (120-160 °C, 10-20 min) were performed. After all treatments, protein content, the amygdalin content via HCN, the antioxidant activity, the phenolic compounds and the color values (L, a*, b*, chroma, hue) of the samples were determined. The fat content (%42.99, %44.35, %40.75), protein content (%34.14, %30.36, %29.27) and hydrocyanic acid (HCN) content (mg/kg) of Hacıhaliloğlu, Kabaaşı and Zerdali varieties were 24.56, 30.31 and 1630.66, respectively. Among the methods used to reduce or eliminate the amygdalin content, roasting was found to be the most effective. The amygdalin content of raw Zerdali kernels was 27.64 mg/g, which decreased to 9.77 mg/g after roasting at 160 °C for 10 min. The antioxidant activity was measured at 82.59 mg TE/100 g, but a decrease was observed after treatment with sodium bicarbonate (81.72), ultrasound (57.5), microwave (52.65) and roasting (97.04). © 2025, Inonu University. All rights reserved.
