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    Effects of the copper on the haematology of the Oncorhynchus mykiss
    (2004) Orun I.; Suiçmez M.; Kalkan E.; Ulus E.
    This study has been conducted to observe the effects of copper concentrations on the blood parameters of rainbow trout Oncorhynchus mykiss (Walbaum 1872) through different time (24hr, 48hr and 72hr). While a significant increase was observed in values of WBC, neutrophil, eosinophil, monocyte, MCV, MCH and thrombocyte depending of dose groups and time periods, a significant decrease was determined in values of lymphocyte, erythrocyte, haemoglobin and hematocrit. But we couldn't observe a significant changes in values of basophil and MCHC. When the dose amount and exposure time were increased, the blood abnormalities became clearer. We can say that the fish have a macrocytic anaemia because of the increase in their mean cell volume (MCV), besides the decrease in their red blood cell (RBC), haemoglobin (Hb) and hematocrit (PCV).
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    Modulating effect of selenium on gills of fish exposed to heavy metals
    (2011) Orun I.; Talas Z.; Alkan A.
    The present study was performed to understand the preventive effect of selenium (Se4+) on heavy metal stress induced by Cd2+ and Cr3+ in rainbow trout. Changes in glutathione peroxidase (GSH-Px), catalase (CAT) and superoxide dismutase (SOD) activity, and in malondialdehyde (MDA) level in gill tissue of rainbow trout after 7 days of exposure to Cd 2+ and Cr3+ were investigated in the presence and absence of Se4+. Heavy metals treated groups exhibited significant decreases (P<0.05) in GSH-Px, CAT, SOD activities of gill, and an increase (P<0.05) in MDA levels, compared to the control. In the presence of Se4+, GSH-Px activity and SOD activity were found to be higher and MDA levels were lower compared with in its absence. In the light of our findings, it could be stated that Cd2+ and Cr3+ lead to dramatic changes in biochemical parameters and selenium caused these parameters to converge to control levels when it was administered concurrently with these heavy metals. Selenium fully or partially restored enzyme activities. Lipid peroxidation was also decreased in selenium treated groups. © by psp.