Yazar "Ozcan, Hamdi" seçeneğine göre listele
Listeleniyor 1 - 9 / 9
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Ciprofloxacin-induced urticaria and tenosynovitis: A case report(Karger, 2008) Kayabas, Uner; Yetkin, Funda; Firat, Ahmet K.; Ozcan, Hamdi; Bayindir, YasarBackground: Tendon disorders are rare events associated with fluoroquinolone congestion. Skin reactions are more frequent than tendon disorders. We reported this case as the combination of ciprofloxacin-induced urticaria and tenosynovitis has been unreported in young women. Case: A 28-year-old woman without underlying disease developed urticarias and tendinopathy 4 days after the initiation of ciprofloxacin treatment for urinary infection. MRI of the left foot revealed increased synovial fluid surrounding the tendon of the flexor hallucis longus muscle representing tenosynovitis. Ciprofloxacin was ceased due to the possibility of ciprofloxacin-induced tendinopathy and urticaria. Complete resolution of her symptoms and findings occurred 3 days after discontinuation of ciprofloxacin without any additional treatment. Conclusion: Early discontinuation of fluoroquinolone therapy when tendinopathy is suspected is the basis of therapy. So, it should be kept in mind that fluoroquinolone-induced tendinopathy may occur in an otherwise healthy young patient with no risk factors and in a site other than the Achilles tendon. Copyright (C) 2008 S. Karger AG, Basel.Öğe Diagnostic potential of serum N-terminal pro-B-type brain natriuretic peptide level in detection of cardiac wall stress in women with polycystic ovary syndrome: a cross-sectional comparison study(Oxford Univ Press, 2007) Celik, Onder; Sahin, Ibrahim; Celik, Nilufer; Hascalik, Seyma; Keskin, Lezzan; Ozcan, Hamdi; Uckan, AhmetBACKGROUND: In addition to the negative effect on fertility, polycystic ovary syndrome (PCOS) has been associated with cardiac pathology. Brain natriuretic peptide (BNP) is a possible marker for cardiac risk, therefore we investigated whether N-terminal pro-B-type BNP (NT-proBNP) increases in women with PCOS compared with healthy women of comparable age and body mass index. METHODS: Thirty women with PCOS and 30 healthy women not suffering from overt cardiac disease were involved in the study. Fasting insulin and serum NT-proBNP levels were measured, and M-Mode echocardiography was performed. Insulin resistance was calculated using the homeostasis model assessment insulin resistance index (BOMA-IR). RESULTS: PCOS subjects had higher NT-proBNP levels than the control subjects (P < 0.001). Abnormal echocardiography indices were detected in 14 of the PCOS subjects (but none of the controls), including valvular heart disease in nine, diastolic dysfunction in two, right ventricular enlargement in one, right atrial enlargement in one and pulmonary hypertension in one. PCOS subjects (n = 30) showed an increased left ventricular mass (LVM) (P < 0.001) and left ventricular posterior wall thickness (LVPWT) (P = 0.006). In addition, NT-proBNP concentration was positively correlated with LVM (r = 0.587, P = 0.001) and negatively correlated with sex-hormone-binding globulin (r = -0.528, P = 0.003). There was a positive correlation between LVM and HOMA-IR (r = 0.295, P = 0.03) while LVPWT was positively correlated with fasting insulin and HOMA-IR (r = 0.335, P = 0.031 and r = 0.346, P = 0.045, respectively) in PCOS subjects (n = 30). CONCLUSION: The present study demonstrated that the level of NT-proBNP was increased in PCOS subjects with asymptomatic heart disease.Öğe The effects of sebum configuration on Demodex spp. density(Tubıtak scıentıfıc & technıcal research councıl turkey, ataturk bulvarı no 221, kavaklıdere, ankara, 00000, turkey, 2016) Demirdag, Hatice Gamze; Ozcan, Hamdi; Gursoy, Sule; Beker Akbulut, GulcinBackground/aim: Demodex spp. are ectoparasites living in the pilosebaceous units, which feed on the host's sebum and cellular proteins. The protective barrier of the skin consists of sebum secretion, moisture, and the acid mantle. In this study, we aimed to determine the effects of skin sebum, moisture, pH levels, and sebum configuration on Demodex spp. density Materials and methods: Forty-five patients who had demodicosis were enrolled in the study group, while the control group consisted of 40 subjects without demodicosis. Body fat percentage, serum triglyceride and cholesterol levels, skin sebum, moisture, and pH levels were measured. Demodex spp. density was determined with a standardized skin surface biopsy. Sebum samples were taken from the forehead and a high-performance thin-layer chromatography (HPTLC) method was performed on these samples. Subsequently, densitometric analyses were applied to the HPTLC plates. Results: Demodex spp. were found on the cheeks and lived in an alkali environment. Skin sebum and moisture levels were low in all groups. The skin pH levels and cholesterol ester in the sebum configuration were determined to be significantly higher in the group with demodicosis. Conclusion: We suggest that Demodex spp. may use cholesterol ester in the sebum as nutriment. In other words, cholesterol ester may be a suitable growth medium for the proliferation of Demodex spp.Öğe Evaluation of 23 cutaneous anthrax patients in eastern Anatolia, Turkey: diagnosis and risk factors(Wiley, 2008) Ozcan, Hamdi; Kayabas, Uner; Bayindir, Yasar; Bayraktar, Mehmet R.; Ay, SelmaBackground Anthrax is a potentially fatal zoonotic disease. The diagnosis of cutaneous anthrax (CA) may be very difficult, particularly in atypical presentations and nonendemic regions. Aim To evaluate the clinical features and diagnostic difficulties of 23 anthrax cases seen between May 2004 and September 2006. Methods Twenty-three patients with CA were included in this study. The diagnosis of CA was based on clinical findings and/or microbiologic procedures. Results All patients with a diagnosis of CA were followed up. One patient experienced toxemic shock. Twenty-two patients had a history of animal contact. Only one patient did not recall any history of suspicious contact. The clinical presentation of CA was typical in 20 patients (87%). Two patients were initially misdiagnosed with insect bites and one patient with angioedema. Cultures from the lesions were positive for Bacillus anthracis in seven cases (30.4%). Gram stain from the lesions revealed Gram-positive rods in eight cases (34.8%). Fifteen patients (65.2%) were diagnosed by clinical presentation and a history of contact with sick animals and/or contaminated animal products. Conclusions CA is a very contagious and important infectious disease worldwide. Early and accurate diagnosis dramatically affects the prognosis of the disease. The diagnosis of CA may be difficult, especially in atypical presentations and nonendemic areas. Thus, CA should be kept in mind, especially in these situations.Öğe Investigation and analysis of a human orf outbreak among people living on the same farm(Edizioni Int Srl, 2011) Bayindir, Yasar; Bayraktar, Mehmet; Karadag, Nese; Ozcan, Hamdi; Kayabas, Uner; Otlu, Baris; Durmaz, RizaHuman orf is a viral zoonotic infection caused by Parapoxvirus. The skin lesions of human orf can be misdiagnosed as cutaneous anthrax leading to overtreatment and also fear This study was conducted to analyze an outbreak which led to deaths among kids and lambs in the same flock, and skin lesions in some persons who were living on the same farm that were initially diagnosed as cutaneous anthrax by a practitioner. Eight patients with skin lesions and eleven persons who had no skin lesion were considered as patients and control groups, respectively The cultures obtained from the lesions of all patients were negative for Bacillus anthracis. The diagnosis of skin lesions was done by clinical findings, histopathological examination and PCR as human if. To be under 20 years of age, direct contact with the animals, and contact with flayed skin of sick animals were the risk factors for human if (Odds Ratio 7.5; 95% Confidence Interval 1.02-54.54, OR 12.25; 95% CI:1.3-100.9, OR 16.67; 95% CI:1.65-148.20, respectively). Orf should be kept in mind in the differential diagnosis of skin lesions resembling anthrax. For control and prevention of orf, transmission routes should be known; good hand hygiene and other personal protective measures have to be implemented.Öğe Prophylactic Antiviral Treatment in Recurrent Herpes Zoster: A Case Report(Galenos Publ House, 2011) Bayram, Hatice Gamze; Ozcan, Hamdi; Bayindir, YasarHerpes zoster (HZ) occurs in older ages with activation of varicella-zoster virus (VZV) which persists in a dormant phase within the dorsal root ganglia. The incidence of HZ in immunosuppressed patients is 20-100 times higher and the clinical progress is more severe than in immunocompetent individuals. A 48-year-old man who had been diagnosed with acute myelocytic leukemia type M3 and had been treated with immunosuppressive agents was admitted to our clinic. The patient was clinically diagnosed as having HZ. He was treated with acyclovir 800 mg five times daily for 7 days. In the consecutive three months, he attended our clinic again with similar complaints. The left cervical (C)5, C6 dermatomes were involved at the fourth attack of HZ. Multinucleated giant cells were determined on the Tzanck smear. VZV DNA was detected by polymerase chain reaction (PCR). Treatment with valacyclovir 1 g three times daily for 14 days was prescribed and then, prophylactic treatment with valacyclovir 500 mg two times a day was administered. Although immunosuppressive treatment was continued, no new attacks of herpes zoster occurred. We think that prophylactic antiviral therapy should be initiated in immunosuppressive individuals who have recurrent herpes zoster attacks.Öğe Relation between Psoriasis and Helicobacter pylori(Galenos Yayincilik, 2011) Turkmen, Dursun; Ozcan, Hamdi; Kekilli, ErsoyObjective: Psoriasis is a common, chronic, inflammatory and hyperproliferative skin disease. It was aimed to detect the role of H. pylori in triggering psoriasis. Materials and Methods: A total of 56 clinically diagnosed psoriatic patients who applied to the dermatology outpatient clinic, were included in the study. As the control group, 57 patients who do not have psoriasis and H. pylori associated dermatologic diseases were included in the study. All patients and control group were tested for H. pylori by the urea-breath test (UBT). Results: Thirty-eight (67.9%) of 56 psoriasis patients (mean age 38.4 +/- 14.08 years; 32 men, 24 women) and 38 (66.7%) of 57 control group (men age, 37.9 +/- 13.73 years; 26 men, 31 women) were positive for H. pylori. There was no statistically significant difference between psoriasis patients and controls with respect to the urea breath test (p=0.89). UBT was positive in all patiens who have gastrointestinal reflux. Conclusion: We could not determine the role of H. pylori in psoriasis. There have been some reports about the association of H. pylori and palmoplantar pustular psoriasis. Therefore, we believe that there is a need for newer studies in a large psoriasis group with tests which have higher specificity and sensitivity.Öğe Toxic epidermal necrolysis due to concomitant use of valproic asid and lamotrigine(Deri Zuhrevi Hastaliklar Dernegi, 2015) Ozcan, Hamdi; Cenk, Hulya; Cumurcu, BirgulToxic epidermal necrolysis (TEN) is a rare but life-threatening acute mucacutaneous hypersensitivity reaction, usually related to medications. Concomitant use of lamotrigine and valproic acid can cause this serious reaction. A 36-year-old male was admitted to the emergency department with the complaints of high fever, burning sensation at eyes, oral and genital mucous erosions, generalized rush and weakness. He had been taking valproic asid, olanzapine, and sertraline for bipolar affective disorder. Lamotrigine 25 mg/day treatment was added to his treatment protocol 15 days before the rush and lamotgine dose was increased 50 mg/day 10 days later. The patient was diagnosed with TEN caused by concomitant use of valproic acid and lamotrigine. The patient was followed up and treated at the burn unit with intravenous immunoglobulin, corticosteroid and antibiotics. Concomitant use of valproic acid and lamotrigine increases the frequency of adverse reaction. TEN may cause serious complications and death. Patients with TEN should be followed by a multi-disciplinary team. Early determination of complications and suitable management can increase the odds for survival.Öğe Ülseratif Kolit Ve Hipertiroidi İle Birlikte Görülen Piyoderma Gangrenozum Olgusu+(Turgut Özal Tıp Merkezi Dergisi, 1999) Ozcan, Hamdi; Akdaş, Ahmet; Aşçıoğlu, ÖzcanPyoderma gangrenozum nadir görülen hasarlayıcı, inflamatuar bir deri hastalığıdır. Ağrılı nodul veya püstül şeklinde başlayan lezyonlaıdan kenarları deriden kabarık, dokunmakla hassas, kenar kısımlarının altı oyuk, giderek genişleme eğilimi gösteren ülser gelişir. Lezyonlar, ülseratif kolit, Crohn hastalığı, poliartrit, gammopati gibi sistemik hastalıklarla birlikte veya altta yatan bir hastalık olmaksızın tek veya çok sayıda olabilirler. Burada piyoderma gangrenozum ile birlikte ülseratif kolit ve hipertiroidi görülen bir olgu sunulacaktır.
