Yazar "Ozcan, Ozlem" seçeneğine göre listele
Listeleniyor 1 - 20 / 32
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Antibodies to Borna Disease Virus in Children with Attention Deficit-Hyperactivity Disorder Borna disease virus serology in Attention Deficit-Hyperactivity Disorder(Universitatsverlag Ulm Gmbh, 2009) Ozcan, Ozlem; Gungor, Serdal; Helps, Chris R.; Turan, Nuri; Tabel, Yilmaz; Saget, Hasan; Yilmaz, HueseyinBorna disease virus (BDV) causes behavioral disorders in rats infected in the newborn period. We investigated BDV serology in children with attention deficit hyperactivity disorder (ADHD). Method: Ninety-nine children with ADHD (mean age: 8.7 +/- 2.5) and 104 control children (mean age: 8.4 +/- 2.8) were included in the study. All sera were investigated using the Enzyme-Linked Immunosorbent Assay (ELISA) method for BDV antibodies. Results: The rate of sero-positivity was 2% (2 of 99) in ADHD and 3.8% (4 of 104) in the control group. There was no significant difference between ADHD and control group for BDV sero-positivity. Conclusion: Our results do not support a role of BDV infections in the pathogenesis of ADHD.Öğe Aripiprazole-related alopesia: A case report(Inonu University Faculty of MediciInonu University Faculty of Medicine, Department of Child and Adolescent Psychiatry, Malatya, Turkey, 2017) Demir, Arzu Caliskan; Ozcan, Ozlem[Abstract Not Acailable]Öğe Aripiprazole-related alopesia: A case report(2017) Caliskan Demir, Arzu; Ozcan, OzlemÖğe Association of Reactive-Proactive Aggression and Anxiety Sensitivity with Internalizing and Externalizing Symptoms in Children with Attention-Deficit/Hyperactivity Disorder(Springer, 2017) Bilgic, Ayhan; Tufan, Ali Evren; Yilmaz, Savas; Ozcan, Ozlem; Ozmen, Sevgi; Oztop, Didem; Turkoglu, SerhatThis study evaluates the associations among the symptoms of anxiety, depression, and disruptive behavioral disorders (DBD) in the context of their relationships with reactive-proactive aggression and anxiety sensitivity in children with attention-deficit/hyperactivity disorder (ADHD). The sample consisted of 342 treatment-naive children with ADHD. The severity of ADHD and DBD symptoms were assessed via parent-and teacher-rated inventories. Anxiety sensitivity, reactive-proactive aggression and severity of anxiety and depression symp-toms of children were evaluated by self-report inventories. According to structural equation modeling, depression and anxiety scores had a relation with the DBD scores through reactive-proactive aggression. Results also showed a negative relation of the total scores of anxiety sensitivity on DBD scores, while conduct disorder scores had a positive relation with anxiety scores. This study suggests that examining the relations of reactive-proactive aggression and anxiety sensitivity with internalizing and externalizing disorders could be useful for understanding the link among these disorders in ADHD.Öğe Association of reactive-proactive aggression and anxiety sensitivity with ınternalizing and externalizing symptoms in children with attention-deficit/hyperactivity disorder(Sprınger, 233 sprıng st, new york, ny 10013 usa, 2017) Ozcan, Ozlem; Yilmaz, Savas; Tufan, Ali Evren; Bilgic, AyhanThis study evaluates the associations among the symptoms of anxiety, depression, and disruptive behavioral disorders (DBD) in the context of their relationships with reactive-proactive aggression and anxiety sensitivity in children with attention-deficit/hyperactivity disorder (ADHD). The sample consisted of 342 treatment-naive children with ADHD. The severity of ADHD and DBD symptoms were assessed via parent-and teacher-rated inventories. Anxiety sensitivity, reactive-proactive aggression and severity of anxiety and depression symp-toms of children were evaluated by self-report inventories. According to structural equation modeling, depression and anxiety scores had a relation with the DBD scores through reactive-proactive aggression. Results also showed a negative relation of the total scores of anxiety sensitivity on DBD scores, while conduct disorder scores had a positive relation with anxiety scores. This study suggests that examining the relations of reactive-proactive aggression and anxiety sensitivity with internalizing and externalizing disorders could be useful for understanding the link among these disorders in ADHD.Öğe Attachment styles in women with vaginismus(Cumhurıyet unıv tıp fak psıkıyatrı anabılım dalı, cumhurıyet unıv tıp fak psıkıyatrı abd, sıvas, 58140, turkey, 2015) Ozcan, Ozlem; Elbozan Cumurcu, Birgul; Karlidag, Rifat; Unal, Suheyla; Aktan Mutlu, Elif; Kartalci, SukruObjective: Attachment styles reflect individual differences in beliefs about oneself and others, interpersonal functioning and close relationships. This study intended to investigate attachment styles of vaginismus patients. Methods: Our sample was included 56 patients with vaginismus and 51 healthy women. Golombok Rust Inventory of Sexual Satisfaction Scale (GRISS) and Relationship Scales Questionnaire (RSQ) were administered to the patients and healthy control group. Results: The scores of the vaginismus group for secure attachment scores were statistically significantly lower than the healthy control group while there was no difference between the groups for the fearful, preoccupied and dismissive attachment subscale scores. GRISS total and subscale scores were statistically higher in women with an insecure attachment style when the total sample as divided into two groups as secure and insecure attached individuals. Conclusions: These findings taken together support the notion that insecure attachment may be an important factor in the pathogenesis of vaginismus.Öğe Biopsychosocial variables associated with gender of rearing in children with male pseudohermaphroditism(Turkiye Sinir Ve Ruh Sagligi Dernegi, 2007) Uslu, Runa; Oztop, Didem; Ozcan, Ozlem; Yilmaz, Savas; Berberoglu, Merih; Adiyaman, Pelin; Cakmak, MuratObjective: The effect of parental rearing on gender identity development in children with ambiguous genitalia remains controversial. The present study aimed to address this issue by investigating the factors that may be associated with sex of rearing in children with male pseudohermaphroditism. Method: The study included 56 children with male pseudohermaphroditism that were consecutively referred to a child psychiatry outpatient clinic. At the time of referral the age range of the sample was 6 months-14 years, 28 children hod been raised as boys and 28 as girls. Demographic and biological information was obtained from patient charts. An intersex history interview was administered to the children and parents, whereas The Gender Identity Interview and the Draw-A-Person Test were administered only to the children. The children were observed during free play. Comparisons of biological, psychological and social variables were made with respect to gender of rearing. Results: More children reared as boys were younger at time of referral, belonged to extended families, and had higher Proder scores. Although children's gender roles were appropriate for their gender of rearing, findings of the Gender Identity Interview and the Draw-A-Person Test suggested that some of the girls presented with a male or neutral gender self-perception. Conclusion: The relationships between age at the time of problem identification, age at the time of diagnosis, and gender of rearing indicate the importance of taking measures to ensure that the intersex condition is identified at birth and children ore referred for early diagnosis, gender assignment, and treatment.Öğe Does Toxoplasma gondii play a role in obsessive-compulsive disorder? Response(Elsevier Ireland Ltd, 2012) Miman, Ozlem; Mutlu, Elif Aktan; Ozcan, Ozlem; Atambay, Metin; Karlidag, Rifat; Unal, Suheyla[Abstract Not Available]Öğe EEG and MRI findings and their relation with intellectual disability in pervasive developmental disorders(Zhejiang Univ Press, 2009) Unal, Ozlem; Ozcan, Ozlem; Oner, Ozguer; Akcakin, Melda; Aysev, Ayla; Deda, GuelhisBackground. The diagnostic category pervasive developmental disorders (PDDs) refer to a group of five disorders: autism, Rett syndrome, childhood disintegrative disorder, Asperger syndrome, and pervasive developmental disorder not otherwise specified (PDD-NOS). EEG abnormalities and seizures are considered much frequent in autistic subjects with comorbid intellectual disability (ID). In this study, we aimed to evaluate the EEG and MRI findings and their relation with ID in pervasive developmental disorder. Methods: A retrospective, cross-sectional and non-experimental study was performed. Subjects included 81 patients diagnosed with autism or PDD-NOS according to the DSM-IV criteria. The age range of the patients was 2-15 years (mean 6.6 years, SD 3.0). Among them, 21 (25.9%) were girls and 60 boys (74.1%). Results: Patients with severe ID had a higher rate of EEG abnormalities (P=0.03) than patients without ID as well as patients with mild or moderate ID. The association remained significant after the structural MRI abnormalities were controlled (P=0.04). The severity of ID was not associated with abnormal MRI. The most frequent EEG and MRI abnormalities were active epileptic anomaly/paroxysmal abnormality and cerebral atrophy/periventricular leukomalacia, respectively. Almost a third of the EEG abnormalities were associated with temporal cortex and adjacent cortical structures. Conclusions: Consistent with previous studies, almost a fourth of the patients in this relatively large sample of patients with pervasive developmental disorders had EEG and/or MRI abnormalities. EEG results indicate that temporal cortex may play a significant role in pervasive developmental disorders.Öğe Heart rate variability as an indicator of autonomous nervous system activity in children withattention deficit hyperactivity disorder(Cumhurıyet unıv tıp fak psıkıyatrı anabılım dalı, cumhurıyet unıv tıp fak psıkıyatrı abd, sıvas, 58140, turkey, 2018) Yuksel, Tugba; Ozcan, OzlemObjective: The aim of the present study was to evaluate heart rate variability (HRV) in children newly diagnosed as attention-deficit/hyperactivity disorder (ADHD). Methods: A total of 51 children with new ADHD diagnosis who were not received any treatment formed the study group and 51 age and sex-matched healthy children were enrolled as the control group. 24-hour heart rate (HR) recordings were performed with rhythm Hotter monitoring and HRV parameters indicating autonomous nervous system (ANS) functions were evaluated. Children in ADHD group were further divided into two groups as 'severe' and 'mild' ADHD according to Clinical Global lmpressions-ADHD-Severity scale. Results: HRV parameters were comparable between ADHD and control groups. Whereas, percentage of consecutive NN intervals over 50 msn (pNN50) and minimum Spectral Power per hour (minSPH) values were lower; while, maximum 1-hour heart rate Hotter (maxHRH) and mean heart rate (HR) values were higher in severe ADHD group than those of control group. Conclusion: These results support that as the severity of ADHD increases, ANS dysfunction becomes more overt. Further large scale, multi-centered, randomized-controlled clinical trials are needed to clarify possible role of ANS dysfunction in ADHD etiopathogenesis.Öğe Is there any role of Toxoplasma gondii in the etiology of obsessive-compulsive disorder?(Elsevier Ireland Ltd, 2010) Miman, Ozlem; Mutlu, Elif Aktan; Ozcan, Ozlem; Atambay, Metin; Karlidag, Rifat; Unal, SuheylaObsessive-compulsive disorder (OCD) is a common psychiatric illness. Although the aetiology of OCD is still unknown, the family-genetic data show that familial forms of OCD may be associated with a specific genetic susceptibility. Recent investigations have associated development of OCD with infectious illness. Toxoplasmic encephalitis (TE) is a common presentation of Toxoplasma gondii infection of the central nervous system (CNS). The most commonly affected CNS region in TE is the cerebral hemisphere, followed by the basal ganglia, cerebellum and brain stem. The basal ganglia has been implicated in the development of OCD. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD. We selected 42 patients with OCD and 100 healthy volunteers, and investigated the sero-positivity rate for anti-Toxoplasma IgG antibodies by Enzyme Linked Immunosorbent Assay (ELISA). The sero-positivity rate for anti-T. gondii IgG antibodies among OCD patients (47.62%) was found to be significantly higher than the rate in healthy volunteers (19%). This is the first report to examine a potential association between Toxoplasma infection and OCD. The main finding of the present study is an increased level of IgG antibodies to T. gondii in OCD patients when compared with the level in healthy controls. There might be a causal relationship between chronic toxoplasmosis and the aetiology of OCD. (C) 2010 Elsevier Ireland Ltd. All rights reserved.Öğe Management of Hepatotoxicity Induced by the Use of Olanzapine(Mary Ann Liebert, Inc, 2017) Donmez, Yunus Emre; Ozcan, Ozlem; Soylu, Nusret; Sarioglu, Fatma Kartal; Selimoglu, AyseNumerous drugs cause hepatotoxicity clinically or biologically. Neuropsychiatric drugs constitute 16% of these drugs. The occurrence of hepatotoxicity induced by the use of olanzapine is expressed by the researchers. In such cases, generally the dose of olanzapine is reduced or the drug is completely discontinued and the treatment of the patient fails. The aim of this study is to report the case for whom elevated liver enzymes were observed but the process was managed without changing treatment dose and drug and to discuss this case with literature information. The present study has characteristics of being the first in the literature concerning management of the process.Öğe Manic attack as a symptom of fluoxetine discontinuation syndrome in a child.(Springer, 2013) Ozcan, Ozlem; Ozdemir, Serdal; Kutuk, Meryem Ozlem[Abstract Not Available]Öğe Manic Symptoms as a Symptom of Antidepressant Discontinuation Syndrome in a Child(Mary Ann Liebert, Inc, 2013) Ozcan, Ozlem; Ozdemir, Serdal; Kutuk, Ozlem Meryem[Abstract Not Available]Öğe Melatonin Treatment for Childhood Sleep Terror(Mary Ann Liebert, Inc, 2014) Ozcan, Ozlem; Donmez, Yunus Emre[Abstract Not Available]Öğe The nutritional behavior of children with autism spectrum disorder, parental feeding styles, and anthropometric measurements(Taylor & Francis Ltd, 2022) Demir, Arzu Caliskan; Ozcan, OzlemBackground Although autism spectrum disorder (ASD) is known to include problems relating to nutrition, information about nutritional behavior, caregiver feeding styles, and anthropometric measurements is still limited. Aims We aimed to assess the nutritional behavior, anthropometric measurements, and caregiver feeding styles of children with ASD. Method One hundred and four children with ASD and 100 controls were enrolled in the study. Children's weight and height were measured and recorded by the researchers. The Children's Eating Behavior Questionnaire, Parental Feeding Style Questionnaire, Development Assessment Form, and Sociodemographic Data Form were conducted by their caregivers. Results Children with ASD were difficult to feed as babies, experienced more problems in the transition to supplementary food, were more selective about food, and were fed diets with a more limited variety than the control group. The BMI z-scores for children with ASD were higher than those for children without ASD, while their height z-scores were lower. Children with ASD displayed more responsiveness to food, emotional overeating, enjoyment of food, desire for drinks, emotional undereating, and food selectivity behaviors, while the parents of these children were found to use more emotional feeding, instrumental feeding, and tolerance-controlled feeding styles than the parents of the controls. Conclusions Children with ASD are more selective about foods and have greater difficulty in switching to supplementary food. The BMI-z score for children with ASD is higher and the height-z score is lower. Children with ASD have different eating and feeding styles compared to children in the control group.Öğe P50 Sensory Gating in Children and Adolescents with Developmental Stuttering(Kure Iletisim Grubu A S, 2009) Ozcan, Ozlem; Altinayar, Sibel; Ozcan, Cemal; Unal, Suheyla; Karlidag, RifatObjective: Stuttering is a speech disorder, where speech fluency is disturbed by the involuntary repetition and prolongation of words and syllables. Its cause is not fully known. Sensory gating is an essential part of information processing and developing an appropriate behavioral response in the brain. Psychological, social, and learning-related factors together with sensorymotor variables play an important role in ensuring fluent speech. Sensory gating protects the brain from overload by filtering the redundant or potentially irrelevant information from the continuous and intensive stream of information. A lack of sensory gating for auditory stimuli may lead to disturbed auditory signal processing and auditory feedback and result in loss of speech fluency. Our aim in this study was to evaluate the state of sensory gating in children and adolescents with developmental stuttering using P50 suppression to test our hypothesis that sensory gating may be disturbed in stuttering. Method: A total of 20 stuttering children and adolescents in 7-18 age group and 20 age-and sex-matched healthy controls with no speech problems were included in the study. All children underwent psychiatric evaluation by a pediatric psychiatrist. Patients with psychiatric, neurological or chronic disease, those who had a history of using medication that could affect the central nervous system and children with a family history of schizophrenia were excluded from the study. P50 suppression was then recorded with an electroencephalogram (EEG). Statistical analysis was performed using the SPSS package software program. The Mann-Whitney U test was used to compare the P50 values of the two groups and p value <0.05 was considered significant for all analyses. Results: The mean age for the children and adolescents included in the study was 11.8 +/- 2.7 years and the age stuttering started was 4.6 +/- 1.1 years. There were 16 males (80%) and 4 females (20%) in both groups. There was no statistically significant difference between the P50 amplitude, latency and P50 suppression ratios of the two groups. Conclusion: The results of this study have shown no association between P50 and stuttering in children and adolescents. However, this first study evaluating sensory gating in children and adolescents should be repeated with prepulse inhibition, another test used to evaluate sensory gating, on larger samples and in different age groups.Öğe Plasma leptin, adiponectin, neuropeptide y levels in drug naive children with adhd(Sage publıcatıons ınc, 2455 teller rd, thousand oaks, ca 91320 usa, 2018) Ozcan, Ozlem; Arslan, Muejgan; Guengoer, Serdal; Yueksel, Tugba; Selimoglu, Mukadder AyseObjective: ADHD is one of the most common childhood psychiatric disorders. Research indicates that there is some link between obesity/overweight and ADHD, though the mechanism of this association remains uncertain. It is the aim of the present study to explore the association between ADHD, obesity, and plasma leptin, neuropeptide Y (NPY), and adiponectin levels. Method: Thirty-six patients diagnosed with ADHD were included in the study. The control group consisted of 40 healthy children and adolescents who had similar age and gender features with the patient group. Plasma leptin, adiponectin, NPY levels were measured, and body mass index (BMI), weight for height, and standard deviation scores (SDS) of height, weight, and BMI were calculated. Results: No significant difference was found between patients and healthy children in terms of BMI and BMI percentile. Participants were classified into three groups according to their weight to height values. There was no significant difference between the two groups, but 10% of the control group and 30.6% of the ADHD group were classified as overweight, which was 3 times higher than the control group. The adiponectin plasma level was significantly lower and leptin/adiponectin (L/A) ratio was significantly higher in the ADHD group. There was no significant difference between serum NPY levels. In the ADHD group, the mean leptin plasma level was high, but was not statistically significant. Conclusion: We think that a low adiponectin level and high L/A ratio may be the underlying mechanism of the obesity in ADHD patients.Öğe Plasma Leptin, Adiponectin, Neuropeptide Y Levels in Drug Naive Children With ADHD(Sage Publications Inc, 2018) Ozcan, Ozlem; Arslan, Muejgan; Guengoer, Serdal; Yueksel, Tugba; Selimoglu, Mukadder AyseObjective: ADHD is one of the most common childhood psychiatric disorders. Research indicates that there is some link between obesity/overweight and ADHD, though the mechanism of this association remains uncertain. It is the aim of the present study to explore the association between ADHD, obesity, and plasma leptin, neuropeptide Y (NPY), and adiponectin levels. Method: Thirty-six patients diagnosed with ADHD were included in the study. The control group consisted of 40 healthy children and adolescents who had similar age and gender features with the patient group. Plasma leptin, adiponectin, NPY levels were measured, and body mass index (BMI), weight for height, and standard deviation scores (SDS) of height, weight, and BMI were calculated. Results: No significant difference was found between patients and healthy children in terms of BMI and BMI percentile. Participants were classified into three groups according to their weight to height values. There was no significant difference between the two groups, but 10% of the control group and 30.6% of the ADHD group were classified as overweight, which was 3 times higher than the control group. The adiponectin plasma level was significantly lower and leptin/adiponectin (L/A) ratio was significantly higher in the ADHD group. There was no significant difference between serum NPY levels. In the ADHD group, the mean leptin plasma level was high, but was not statistically significant. Conclusion: We think that a low adiponectin level and high L/A ratio may be the underlying mechanism of the obesity in ADHD patients.Öğe Psychometric properties of the DY-BOCS in a Turkish sample of children and adolescents(W B Saunders Co-Elsevier Inc, 2016) Guler, Aysegul Selcen; do Rosario, Maria Conceicao; Ayaz, Ayse Burcu; Gokce, Sebla; Yulaf, Yasemin; Basgul, Senem; Ozcan, OzlemBackground: Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) is a promising scale for assessing frequency and severity of symptom dimensions. The main objective of the study was to assess the psychometric properties of the DY-BOCS in a large sample of children and adolescents from Turkey. Methods: We studied 143 children and adolescents, 7-18 years, with well characterized DSM-IV-R OCD, ascertained from seven collaborating university or state hospital sites. We compared the DY-BOCS scores with the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), the Children's Depression Inventory (CDI), the Yale Global Tic Severity Scale (YGTSS) and the Child Behavior Checklist 6-18 years (CBCL 6-18). Results: The internal consistency of the DY-BOCS symptom dimensions and inter-rater agreement of component scores were excellent. The agreement between global DY-BOCS score and the total CY-BOCS score was highly significant (Pearson's r = 0.55, p < 0.0001). Severity scores for individual symptom dimensions were independent of one another, only modestly correlating with the global ratings, and were also differentially related to ratings of depression, anxiety and tic severity. Conclusion: The DY-BOCS is a reliable and valid instrument for assessing multiple aspects of OCD symptom severity in children and adolescents from Turkey. (C) 2015 Elsevier Inc. All rights reserved.
