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Öğe Colorectal invasion of endometriosis(2020) Ozdemir, Hakan; Unal Ozdemir, Zehra; Gul, Mehmet OnurAim: Endometriosis is a common gynecological disorder affecting women of reproductive age. The localization and stage of endometriosis determine the clinical course of the disease. In this study, colorectal invasion in endometriosis cases were evaluated retrospectively.Material and Methods: Between January 2011 and December 2019, female patients aged 18-60 that had undertaken colonoscopy examinations, appendectomies, colorectal resections and bowel shave was performed to remove mass in the intestinal wall. All results were evaluated retrospectively. After histopathological examinations, the results obtained, including findings of endometriosis were included in the study.Results: The mean age of patients was found to be 41.78±2.03. 30078 patients who had colonoscopy and rectosigmoidoscopy only two endometriosis was found(0.06%). Five out of 554 colorectal resection specimens (0.9%) and 8 out of 1516 appendectomy specimens were detected with endometriosis. Endometriosis was detected in 3 other cases with an invasive mass on the colon wall during gynecological operations and finally, in one patient holding the entire intestinal system along with the peritoneal surfaces in the abdomen. Altogether 19 cases of endometriosis were detected, 42% was invasion of the appendix tissue (most common) and the rectum being second with 21% most common localization.Conclusion: Colorectal invasion of the endometriosis is a rare clinical condition. The radiological appearance of the lumen obstruction could be confused with malignancy, cases that have not been diagnosed can visit emergency services with ileus due to lumen obstruction. In these cases surgical treatments are the best treatment option.Öğe Effects of Orthodontic Treatment on Patients' Dental Anxiety and Oral Health Knowledge(Aves Press Ltd, 2009) Ozturk, Firat; Sokucu, Oral; Demirer, Serhat; Nalcaci, Ruhi; Ozdemir, HakanThe aim of this study was to investigate effects of orthodontic treatment on both anxiety and oral health knowledge of orthodontic patients. The study was carried out in 184 patients. Four groups were formed according to the stage of orthodontic treatment. Group 1 consisted of 47 individuals selected from patients who were awaiting orthodontic treatment; groups 2 and 3, comprised 44 and 46 individuals who had been undergoing orthodontic treatment for a period of 1-12 and 12-26 months respectively, and group 4, 47 orthodontically treated individuals. The modified Dental Anxiety Scale was used to measure dental anxiety. Oral health knowledge was assessed using several questions concerning etiology, symptoms and prevention. Chi-squire test was used for statistical assessment. The anxiety level of patients in group 1 was significantly higher than the subjects in group 4. Patients in groups 2, 3 and 4 mostly knew that gum bleeding is a sign of periodontal disease (81.8, 84.7, 80.1 per cent respectively); and this was 63.8 per cent for group 1. Patients in all groups were aware how to prevent, however those who were undergoing or had completed treatment were more informed about symptoms of periodontal disease. Only 19.6 and 52.1 per cent of subjects in group 3 had the knowledge to identify dental plaque and what it can cause respectively; which was the highest ratio among the groups. Orthodontic treatment involves some degree of exposure, consequently creates a positive influence on patients' anxiety and periodontal health knowledge.Öğe Stabilization of autotransplanted teeth using thermoplastic retainers(Medicina Oral S L, 2011) Isa-Kara, Muhammed; Sari, Fatih; Emre-Coskun, Mehmet; Kustarci, Alper; Burak-Polat, Hidayet; Ozdemir, Hakan; Polat, SerkanObjective: Different fixation techniques have been used for stabilization of autotransplanted teeth. Because rigid or extended fixation periods can cause complications such as ankylosis and disturbances of pulpal revascularization, our aim was to evaluate an alternative technique, a removable splint, for improving the success rate of autotransplanted molar teeth. Study Design: In 44 patients, (20 male and 24 female patients), 45 transplanted teeth were analyzed. These cases were followed for 31 to 47 months after operation. Transplanted teeth were evaluated after use of a thermoplastic retainer for 1 month, in terms of success rate and dissatisfaction with this apparatus. The primary stability, ankylosis, and root resorption were also analyzed. Results: To date, 1 transplant was extracted after 6 months due to unpreventable periapical root inflammation, and 2 transplants were extracted after one year due to external root resorption. Although 2 ankylosed transplants were still functional after an average follow-up period of three years, with no dissatisfaction by the patients, these cases were treated as failures because of the probable risk for external root resorption. The remaining 40 (88.8 % success rate) transplants remained asymptomatic and functioning for a mean follow-up period of 37 months. In the assessment of dissatisfaction with the thermoplastic retainer, 36 (81.8 %) patients had no or little dissatisfaction, 4 (9 %) patients had very appreciable or excessive dissatisfaction, and 4 (9 %) patients had moderate dissatisfaction. Conclusions: A thermoplastic retainer for use after autotransplantation of third molar teeth is a reasonable and useful method and a good alternative to conventional rigid or semi-rigid splints. This technique was especially useful in autotransplanted teeth that had poor stability, i.e., in cases in which it is conventionally advised to use long-term rigid or semi-rigid splints.Öğe Systemic effects of H2S inhalation at human equivalent dose of pathologic halitosis on rats(Taylor & Francis Ltd, 2017) Yeler, Defne Yalcin; Aydin, Murat; Gul, Mehmet; Hocaoglu, Turgay; Ozdemir, Hakan; Koraltan, MelikeObjectives: Halitosis is composed by hundreds of toxic gases. It is still not clear whether halitosis gases self-inhaled by halitosis patients cause side effects. The aim of the study was to investigate the effect of H2S inhalation at a low concentration (human equivalent dose of pathologic halitosis) on rats. Materials and methods: The threshold level of pathologic halitosis perceived by humans at 250ppb of H2S was converted to rat equivalent concentration (4.15ppm). In the experimental group, 8 rats were exposed to H2S via continuous inhalation but not the control rats. After 50 days, blood parameters were measured and tissue samples were obtained from the brain, kidney and liver and examined histopathologically to determine any systemic effect. Results: While aspartate transaminase, creatine kinase-MB and lactate dehydrogenase levels were found to be significantly elevated, carbondioxide and alkaline phosphatase were decreased in experimental rats. Other blood parameters were not changed significantly. Experimental rats lost weight and became anxious.Histopathological examination showed mononuclear inflammatory cell invasion in the portal areas, nuclear glycogen vacuoles in the parenchymal area, single-cell necrosis in a few foci, clear expansion in the central hepatic vein and sinusoids, hyperplasia in Kupffer cells and potential fibrous tissue expansion in the portal areas in the experimental rats. However, no considerable histologic damage was observed in the brain and kidney specimens. Conclusions: It can be concluded that H2S inhalation equivalent to pathologic halitosis producing level in humans may lead to systemic effects, particularly heart or liver damage in rats.Öğe Ultrastructural changes in epithelial cells of rats exposed to low concentration of hydrogen sulfide for 50 days(Taylor & Francis Inc, 2016) Yeler, Defne Yalcin; Aydin, Murat; Hocaoglu, Peyami Turgay; Koraltan, Melike; Ozdemir, Hakan; Kotil, Tugba; Gul, MehmetHydrogen sulfide (H2S) and other volatile sulfur compounds (VSCs) appear mainly in the oral air of patients with halitosis. It seems that VSCs are directly involved in the pathogenesis of gingival diseases. In previous studies, short-term (7 hours-4 days), high concentrations (5-400 ppm) of H2S applications on periodontal tissues have been evaluated in a culture medium. The aim of the present study was to investigate the potential effects of lower (equivalent to halitosis) concentrations of H2S on rat gingival tissue for longer-term inhalation. The threshold level of pathologic halitosis perceived by humans at 250 ppb of H2S was converted to rat equivalent concentration (4.15 ppm). Rats in the experimental (H2S) group (n=8) were exposed to H2S continuously but not the control rats (n=8). After 50 days, the gingival sulcular tissue samples of each rat were taken and examined using transmission electron microscope. Ultrastructural changes in the sulcular epithelia of the rat gingiva showed deformation of celullar shape, vacuolization, and disintegrity of intercelullar connection by loss of desmosomes and collagen fibrils. No basal membrane damage was observed. Inhalation of low levels of H2S (equivalent of halitosis) in the oral environment causes ultrastructural celullar damages in rat sulcular mucosa. These results suggest that halitosis may be the potential reason for periodontal destruction in humans.
