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    Evalution of Renal Involvement in Patients with Behcet Disease: Need to be Aware About Potential Hypertension in Long Term Follow Up?
    (Int Scientific Information Inc, 2016) Ozel, Deniz; Ozel, Betul Duran; Ozkan, Fuat; Kutlu, Ramazan
    Backround: The aim of this study was to evaluate frequency and severity of kidney involvement with some clinical, ultrasonography and color Doppler measurements in patients with Behcet disease. Material/Methods: This study was including 32 patients with Behcet disease and 32 healthy sex and age-matched control subjects. Patients were divided into two groups as period of disease 0-6 years and 7 years and above to evaluate effect of duration of disease. We evaluated some biochemical tests in both blood and urine related to renal functions, blood pressure values. Gray scale and color Doppler findings were noted. Results: Renal artery volume flow in patients with a duration of 7 years or above was significantly decreased compared to control group (p<0.05). However, gray scale ultrasound and color Doppler measurements reveal there was not statistically significant change compared to control group. There was no biochemical abnormalities in any patient. Four patients had elevated blood pressure but mean blood pressure values were not statistically different compared to volunteers. Conclusions: Renal involvement ratios varies in different studies but not common. End stage renal failure can be seen very rare. Furthermore, vasculitic changes can lead renal artery narrowness and can result to decrease in renal blood flow. It has a potential to activate renin angiotensin aldosterone cascade to elevate blood pressure. We must be aware about blood pressure of patients with Behcet disease, especially with long term follow up.
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    Measurement of Bone Mineral Density in Male Detainees
    (Galenos Yayincilik, 2012) Bakan, Betul; Sucakli, Mustafa Haki; Ozer, Ali; Kalender, Ali Murat; Ozkan, Fuat
    Aim: We aimed to investigate the increased risk for osteoporosis due to closed environment and sedentary lifestyle of prisoners. In his way, we planned to inform prisoners and supervisors for protective measures that should be taken if low bone mineral density (BMD) is detected compared with normal population. Materials and Methods: Sixty six prisoner men over the age of 45 as the study group and 66 male volunteers who are not detainees over the age of 45 as a control group were included in the study. All participants' age, occupation, duration in prison, habits, nutrition, exercise, diseases and medications used were noted. BMD values were measured using a phalangeal radiographic absorptiometry (Alara Metriscan(6)). Results: BMD values in the study group were measured as 0.341 +/- 0.030 g/cm(2) and as 0.346 +/- 029 g/cm(2) in the control group (p=0.968) BMD values of the study group were lower than those of the control group. Conclusion: In this study, we found that BMD values of the detainees were lower than those of the control group but this difference was not statistically significant. However, there was a negative correlation between BMD values and duration in prison.
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    The Osteoporotic Effect of Arteriovenous Fistula on the lpsilateral Upper Extremity in Hemodialysis Patients
    (Galenos Yayincilik, 2013) Bakan, Betul; Kalender, Ali Murat; Ozer, Ali; Sucakli, Mustafa Haki; Ozkan, Fuat; Dogan, Ekrem
    Objective: Hemodialysis requires an arteriovenous fistula (AVF), the presence of which may influence the structure of nearby bone. This study analyzed the effect of AVF on ipsilateral upper extremity bone mineral density (BMD), as measured by phalangeal radiographic absorptiometry (RA). Materials and Methods: In this cross-sectional study, phalangeal BMD was measured in both arms by RA in a convenience sample of end-stage renal disease (ESRD) patients with a forearm AVF Patients were excluded if the patient had pathology which might affect distal arm circulation. BMD values (g/cm(2)) from forearms with AVF were compared with values from forearms without AVF Predialysis values of complete blood count, calcium, phosphorus, alkaline phosphatase, parathyroid hormone, urea, creatinine, potassium, albumin, total cholesterol, HDL cholesterol, and LDL cholesterol were determined in all patients; dialysis adequacy values were also calculated. Results: One hundred and sixteen patients agreed to participate in the study. Thirty-three patients were excluded, thus, data were analyzed from 83 patients (59% male, 41% female, mean hemodialysis time: 156 +/- 6 months, mean age: 53 +/- 16 years). AVFs were located in the nondominant hand in all patients. Phalangeal BMD in forearms with AVF (0.28 +/- 0.05 g/cm(2), range: 0.14-0.40) was significantly lower than that in the contralateral forearm (0.30 +/- 0.04 g/cm2, range: 0.79-0.40, p<0.05). Conclusion: In ESRD patients on hemodialysis, BMD is lower in the ipsilateral-to-AVF hand compared to the contralateral-to-AVF hand. In these patients, further investigations should be made to ascertain the ability of BMD assessment in determining fracture risk and to prompt physicians to initiate treatments which will preserve BMD and reduce fractures.