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  • Küçük Resim
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    Childhood sleep disorders in premature infants that hospitalized in neonatal intensive care unit in neonatal period
    (2020) Barutcu, Adnan; Celik, Gonca; Yapca Kaypakli, Gamze; Ozlu, Ferda; Yapicioglu Yildizdas, Hacer; Satar, Mehmet
    Aim: Children requiring intensive care in the neonatal period have more fine motor injuries, learning difficulties, eating disorders and sleeping problems. Sleep disorder rate is about 10-30% in children who had no problem in newborn period. We aimed to investigate the rate of sleep disorder in children who were hospitalized in the neonatal intensive care unit during the neonatal period. Material and Methods: Fourty-six patients hospitalized in neonatal intensive care unit and still followed in outpatient policlinic at Çukurova University were enrolled in to the study. Children’s Sleep Habits Questionnaire was performed to evaluate sleep resistance, delay in fall into sleep, duration of sleep, sleep anxiety, parasomnia, midnight awakening and daily sleepiness.Results: Children were 6.64±1.18 years old. They were healthy and had no neurological sequela. None of the parents complained about sleep disorders. However, 20 of the 46 (43.47%) children had sleep disorder (Sleep disorder group). Twenty-six children had no sleep disorder (No sleep disorder group). There isn’t any statistically difference between the groups that terms of gestational age, birth weight, ventilator support, gender (p>0.05).Conclusion: Although there isn’t any significant difference between groups, sleep disorder rate is higher compared to normal population’s rates reported in the previous studies. Infants discharged from neonatal intensive care unit should be under evaluation also for sleep disorder.
  • Küçük Resim Yok
    Öğe
    An observational, multicenter, registry-based cohort study of Turkish Neonatal Society in neonates with Hypoxic ischemic encephalopathy
    (Public Library Science, 2023) Okulu, Emel; Hirfanoglu, Ibrahim Murat; Satar, Mehmet; Erdeve, Omer; Koc, Esin; Ozlu, Ferda; Gokce, Mahmut
    Background Hypoxic ischemic encephalopathy (HIE) is a significant cause of mortality and short- and long-term morbidities. Therapeutic hypothermia (TH) has been shown to be the standard care for HIE of infants >= 36 weeks gestational age (GA), as it has been demonstrated to reduce the rates of mortality, and adverse neurodevelopmental outcomes. This study aims to determine the incidence of HIE in our country, to assess the TH management in infants with HIE, and present short-term outcomes of these infants. Methods The Turkish Hypoxic Ischemic Encephalopathy Online Registry database was established for this multicenter, prospective, observational, nationally-based cohort study to evaluate the data of infants born at >= 34 weeks GA who displayed evidence of neonatal encephalopathy (NE) between March, 2020 and April 2022. Results The incidence of HIE among infants born at >= 36 weeks GA (n = 965) was 2.13 per 1000 live births (517:242440), and accounting for 1.55% (965:62062) of all neonatal intensive care unit admissions. The rates of mild, moderate and severe HIE were 25.5% (n = 246), 58.9% (n = 568), and 15.6% (n = 151), respectively. Infants with severe HIE had higher rates of abnormal magnetic resonance imaging (MRI) findings, and mortality (p<0.001). No significant difference in mortality and abnormal MRI results was found according to the time of TH initiation (<3 h, 3-6 h and >6 h) (p>0.05). TH was administered to 85 (34.5%) infants with mild HIE, and of those born of 34-35 weeks of GA, 67.4% (n = 31) received TH. A total of 58 (6%) deaths were reported with a higher mortality rate in infants born at 34-35 weeks of GA (OR 3.941, 95% Cl 1.446-10.7422, p = 0.007). Conclusion The incidence of HIE remained similar over time with a reduction in mortality rate. The timing of TH initiation, whether <3 or 3-6 h, did not result in lower occurrences of brain lesions on MRI or mortality. An increasing number of infants with mild HIE and late preterm infants with HIE are receiving TH; however, the indications for TH require further clarification. Longer follow-up studies are necessary for this vulnerable population.