Yazar "Ozsahin A.D." seçeneğine göre listele

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    Investigating inhibitory effects of punica granatum fruit extracts on lipid peroxidation in the fenton reagent environment
    (Chemical Publishing Co., 2012) Ozsahin A.D.; Kirecci O.A.; Yilmaz O.; Erden Y.; Bircan B.; Karaboga Z.
    In this study, it is aimed to find antioxidant activity of methanolic extract of Punica granatum fruit, by determining a,a-diphenyl-b- picrylhydrazyl (DPPH) radical scavenging property and also by determining the capacity to prevent the formation of lipid peroxidation which is found in in-vitro environment that soybean and corn oils are found. The capacity of preventing lipid peroxidation was analyzed in an in vitro environment that oil samples were existed by evaporating methanol phase of extracts. In the experiment, the groups were formed as control group e.g., Fenton reactive, Pomegranate extract + Fenton reactive. It was observed that the lipid peroxidation level formed on the oils had increased at a significant level when compared to Fenton reactive groups according to the control group. When the extract groups are compared (to each other) according to the Fenton reactive group, it was detected that lipid peroxidation level had significantly decreased (p > 0.0001). According to the scavenging activity of ?,?-diphenyl-?-picrylhydrazyl radical, it was determined that the pomegranate extracts were effective at their highest level at 250-500 ?L (p < 0.0001). It was concluded that Punica granatum effectively decreases the lipid peroxidation level, neutralizes the ?,?-diphenyl-?-picrylhydrazyl free radical and has a characteristic of conserving the fatty acid content.
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    Radical scavenging activities of some Vitis vinifera varieties grown in malatya (Turkey) and their preventive effects on the formation lipid peroxidation in unsaturated fatty acids mediated
    (Chemical Publishing Co., 2010) Ozsahin A.D.; Yilmaz O.; Tuzcu M.; Kirecci O.A.; Guvenc M.
    This study examined the phytochemical characteristics of five samples of Vitis vinifera grown in the Malatya region of Turkey and investigated their impacts on human health by determining their antioxidant activities in vitro. The present research includes five native grape varieties (white: Tahanebi, Sam and Kureys; red: Köhnü; black: Banazi Karasi). Antioxidative activities of the grape extracts were determined with the following modifications. The free radical scavenging effect in extracts was assessed by the decolouration of a methanolic solution of DPPH. Lipid peroxidation level was found to be significantly high in the Fenton reagent (FR) containing group when compared to the control group (p < 0.0001). However, lipid peroxidation level decreased significantly in the groups to which grape extracts were added (p < 0.0001). According to DPPH results, all grape samples showed effective antioxidant activity in different concentrations and these activities were observed to change in parallel with the increase in flavonoid concentration. The results indicate that the grape fruit extracts decrease lipid peroxidation level in the Fenton reagent environment and have scavenging effect on the DPPH depending on grape varieties.