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Öğe Brown syndrome: clinical features and results of superior oblique tenotomy(Consel Brasil Oftalmologia, 2021) Ozsoy, Ercan; Gunduz, Abuzer; Firat, Ilknur Tuncer; Firat, MuratPurpose: This study was conducted to further de-fine the specific clinical characteristics of patients with Brown syndrome and evaluate the outcomes of superior oblique tenotomy in its surgical management. Methods: A retrospective analysis of the medical charts of 45 patients with Brown syndrome was performed, which revealed that 11 patients underwent superior oblique tenotomy due to abnormal head posture and/or hypotropia and 1 patient underwent bilateral superior oblique tendon elongation with a silicone band due to abnormal head posture. In the last patient, silicone bands were removed at the postoperative 3rd month due to the lack of improvement in the abnormal head posture and the limitation of elevation in adduction. Simultaneous horizontal rectus muscle surgery was performed in four patients. Results: There was a predominance of female gender, right eye, congenital form, unilaterality, A-pattern, and an abnormal head posture type with a combination of chin up and head tilting. Bilateral form was observed only in female patients. Amblyopia was detected in two patients. Among patients aged >5 years, 40% had reduced stereopsis. Abnormal head posture was found in 60% of patients. More than half of them were diagnosed with a vertical and/or horizontal deviation. Tenotomy procedure eliminated the abnormal head posture in all patients and significantly improved the mean limitation of elevation in adduction and hypotropia (p=0.001, p=0.012). Two patients developed inferior oblique overaction in the operated eye. There was complete spontaneous resolution in two patients. Conclusions: The clinical features of patients with Brown syndrome in our study are considerably consistent with those of previous reports. The present study demonstrated the effectiveness of superior oblique tenotomy with less overcorrection in the surgical treatment of Brown syndrome.Öğe Changes in Anterior Chamber Parameters with the Pentacam Rotating Scheimpflug and Axial Length Measurements by Ultrasound in Patients Who Use Isotretinoin(Informa Healthcare, 2012) Cumurcu, Tongabay; Sener, Serpil; Ozsoy, Ercan; Doganay, SelimPurpose: Evaluation of changes in anterior chamber parameters with the Pentacam rotating Scheimpflug and axial length measurements (Alx) by ultrasound in patients who use isotretinoin for the treatment of acne vulgaris. Methods: Twenty-nine eyes of 29 patients (15 men, 14 women) were evaluated with the Pentacam before the treatment, and at the 3rd and 6th months of treatment. The axial length was evaluated by ultrasound biometry. The non-parametric paired t-test was used to compare pretreatment and 3rd and 6th month anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA) width, central corneal thickness (CCT), lens thickness (LT), pupil size, axial length measurement (Alx) and mean keratometry values (K). Results: The mean age of the patients was 21.82 +/- 4.14 years. The differences between the pretreatment and 3rd and 6th month ACD, ACV, CCT, Alx, LT and mean K values were statistically significant (p < 0.05). The differences between the pretreatment and 3rd and 6th month pupil size measurements were not statistically significant (p > 0.05). The differences between the pretreatment and 3rd month ACA measurements were statistically significant (p > 0.05), but there was no statistically significant difference with 6th month values (p < 0.05). Conclusions: Isotretinoin treatment causes statistically significant changes in most anterior segment parameters during treatment.Öğe Contact-lens-related corneal ulcer caused by klebsiella pneumoniae(Hospital Clinicas, Univ Sao Paulo, 2011) Cumurcu, Tongabay; Firat, Pembegul; Ozsoy, Ercan; Cavdar, Mufide; Yakupogullari, Yusuf[Abstract Not Available]Öğe Corneal structure in tilted disc syndrome(Consel Brasil Oftalmologia, 2016) Gunduz, Abuzer; Polat, Nihat; Cumurcu, Tongabay; Demirel, ErsinErsan; Ozsoy, ErcanPurpose: To evaluate the central corneal thickness (CCT), corneal volume (CV), and anterior and posterior corneal surfaces using the Scheimpflug imaging system in patients diagnosed with tilted disc syndrome (TDS). Methods: The study group (Group 1) and the control group (Group 2) comprised 35 eyes of 35 age-, sex-, and refraction-matched cases. All cases underwent a full ophthalmic examination that included cycloplegic refraction, axial ocular length measurement, and Scheimpflug imaging. Results: The mean age was 34.68 +/- 15.48 years in Group 1 and 34.11 +/- 12.01 years in Group 2 (p = 0.864). The gender distribution was 18 males and 17 females in Group 1 and 16 males and 19 females in Group 2 (p = 0.618). All subjects were Caucasian. The spherical equivalent was 3.62 +/- 1.75 D in Group 1 and 3.69 +/- 1.51 D in Group 2 (p = 0.850). There was no significant difference in age, sex, race, or spherical equivalent between groups. There was no significant difference in mean keratometric value and CV3 (the CV in the central 3 mm) between groups (p = 0.232 and 0.172, respectively). There were statistically significant differences in CCT, CV5, and CV7 (CV in the central 5 and 7 mm(3), respectively) and total CV between groups (p = 0.008, 0.003, 0.023, and 0.019, respectively). The values of all parameters were lower in the study group than in the control group. There was also a statistically significant difference in the anterior elevation parameters of the cornea between groups (p < 0.05). The mean values of Group 1 were higher than those of Group 2. There were statistically significant differences in the two parameters referring to the posterior elevation of the cornea between the two groups (p < 0.05). Conclusion: The results of this study showed that eyes with TDS have thinner CCT, lower CV, and different anterior corneal curvature than normal eyes.Öğe Duane Retraction Syndrome: Clinical Features and a Case Group-Specific Surgical Approach(Taylor & Francis Inc, 2019) Gunduz, Abuzer; Ozsoy, Ercan; Ulucan, Pamuk BetulPurpose: To describe the clinical features of patients with Duane retraction syndrome (DRS) and evaluate the outcomes of surgical approaches based on the characteristics of each patient. Methods: The records of 38 Caucasian subjects with DRS were retrospectively reviewed. The patients were classified as type I, II, or III based on the Huber Classification. Ten patients underwent unilateral medial rectus (MR) recession due to abnormal head posture (AHP) and/or esotropia. Four patients underwent Y-splitting and recession of the lateral rectus (LR) with MR recession due to AHP and/or esotropia, upshoot, and globe retraction. Results: There was a preponderance of unilaterality, female gender, left eye, type I, orthotropia, upshoot, and low refractive error. All patients demonstrated globe retraction and fissure narrowing. AHP was only present in unilateral cases. Nine patients had amblyopia. More than half of the patients over 5 years of age had decreased stereopsis. MR recession decreased AHP to less than 8 degrees in all patients. Y-splitting and recession of the LR eliminated upshoot in all four patients. One patient who underwent an 8-mm MR recession demonstrated -2 adduction limitation. Conclusions: The DRS patients in our study demonstrated features that are consistent with previous reports in the literature. This study emphasizes the need to consider disease classification in the surgical management of DRS patients.Öğe Effect of inferior oblique anterior transposition in correcting vertical hyperdeviation in primary position(Canadian Ophthal Soc, 2019) Gunduz, Abuzer; Firat, Murat; Ozsoy, Ercan; Cankaya, CemObjective: To evaluate the effect of inferior oblique anterior transposition (IOAT) on improvement of vertical hyperdeviation in primary position. Methods: This study was a retrospective review and included 35 eyes of 33 patients (18 males and 15 females). Patients with dissociated vertical deviation were not included in the study. Preoperative and postoperative average follow-up was 11.46 +/- 11.73 and 11.43 +/- 9.73 months, respectively. The eyes were divided into 5 groups according to the amount of transposition. Inferior oblique muscle was transpositioned 2 mm posterior to the inferior rectus insertion in group 1; 1 mm posterior to the inferior rectus insertion in group 2; parallel to the inferior rectus insertion in group 3; 1 mm anterior to the inferior rectus insertion in group 4; and 2 mm anterior to the inferior rectus insertion in group 5. Results: The mean preoperative and postoperative vertical hyperdeviation were 16.52 +/- 5.54 and 0.97 +/- 2.34 prism diopters (PD), respectively. The mean preoperative vertical hyperdeviation in group 1, group 2, group 3, group 4, and group 5 was 11.0 +/- 4.24, 12.88 +/- 4.26, 16.63 +/- 3.50, 19.83 +/- 2.71, and 25.5 +/- 3.00 PD, respectively. Postoperatively, improvement in vertical hyperdeviation in group 1, group 2, group 3, group 4, and group 5 was 11.0 +/- 4.24, 11.63 +/- 3.20, 15.46 +/- 3.19, 18.17 +/- 2.23, and 25.5 +/- 3.00 PD, respectively. The vertical hyperdeviation had improved 100% in group 1; 90.2% in group 2; 92.9% in group 3; 91.59% in group 4; and 100% in group 5. Conclusion: IOAT surgery planned according to hyperdeviation amount has effective and predictable results in correcting vertical hyperdeviation in primary position.Öğe Estimation of angle kappa and pupil barycentre configuration in myopic tilted disc syndrome(Wiley, 2020) Cankaya, Cem; Ozsoy, Ercan; Demirel, Ersin Ersan; Polat, Nihat; Gunduz, AbuzerBackground To evaluate the angle kappa and pupil barycentre configuration in patients with myopic tilted disc syndrome (TDS). Methods Thirty-five eyes of 35 patients with TDS were included in the study. Thirty-five eyes of 35 age- and sex-matched healthy subjects were enrolled in the control group. All measurements were performed with the Lenstar LS 900. Angle kappa was calculated according to Pythagorean theorem using the x and y co-ordinates of the pupil centre. Pupil dx and pupil dy values (pupil dx: x co-ordinate of pupil centre relative to corneal apex, pupil dy: y co-ordinate of pupil centre relative to corneal apex) were used to evaluate the pupil barycentre configuration. Central corneal thickness, white to white (cornea diameter), pupil diameter, anterior chamber depth, lens thickness, and axial length were also measured. Results The calculated mean angle kappa distance was 0.27 +/- 0.15 mm in the TDS group and 0.29 +/- 0.23 mm in the control group (p = 0.42). The mean pupil dx was -0.01 +/- 0.24 mm in the TDS group and -0.17 +/- 0.14 mm in the control group (p = 0.006). The mean pupil dy was -0.02 +/- 0.13 mm in the TDS group and -0.05 +/- 0.22 mm in the control group (p = 0.65). Conclusions The pupil barycentre in TDS cases was statistically significantly closer to the corneal vertex on the horizontal plane compared to the control group. However, there was no statistically significant differences in terms of angle kappa and pupil dy values between the groups. According to our results, refractive surgery can be performed safely with respect to complications related to decentration of ablation zone and decentration of multifocal intraocular lenses in these groups of patients.Öğe Evaluation of Anterior Segment's Structures in Tilted Disc Syndrome(Hindawi Ltd, 2016) Ozsoy, Ercan; Gunduz, Abuzer; Demirel, Ersin Ersan; Cumurcu, TongabayPurpose. To evaluate anterior segment's structures by Pentacam in patients with tilted disc syndrome (TDS). Methods. Group 1 included forty-six eyes of forty-six patients who have the TDS. Group 2 including forty-six eyes of forty-six cases was the control group which was equal to the study group in age, gender, and refraction. A complete ophthalmic examination was performed in both groups. All cases were evaluated by Pentacam. The axial length (AL) of eyes was measured by ultrasound. Quantitative data obtained from these measurements were compared between two groups. Results. There was no statistically significant difference for age, gender, axial length, and spherical equivalent measurements between two groups (p = 0.625, p = 0.830, p = 0.234, and p = 0.850). There was a statistically significant difference for central corneal thickness (CCT), corneal volume (CV), anterior chamber angle (ACA), and pupil size measurements between two groups (p = 0.001, p = 0.0001, p = 0.003, and p = 0.001). Also, there was no statistically significant difference for anterior chamber depth (ACD), anterior chamber volume (ACV), and lens thickness (LT) measurements between two groups (p = 0.130, p = 0.910, and p = 0.057). Conclusion. We determined that CCT was thinner, CV was less, and ACA was narrower in patients with TDS. There are some changes in the anterior segment of the eyes with tilted disc.Öğe Evaluation of central macular thickness after penetrating keratoplasty(2018) Can, Nagehan; Guler, Mete; Yusufoglu, Elif; Celik, Fatih; Gul, Fatih Cem; Ozsoy, ErcanAim: To evaluate the changes in central macular thickness after penetrating keratoplasty. Material and Methods: A total of 24 eyes of 24 patients who had undergone penetrating keratoplasty were included in the study. This study was performed retrospectively by reviewing the charts of the patients. Postoperative 1st week, 1st month, 3rd month, 6th month and 12th month mean total macular volume, central macular thickness, parafoveal area and perifoveal area thickness and retinal nevre fiber layer (RNFL) thickness results obtained with optic coherence tomography were compared. ANOVA test was used for statistical analysis. Results: The postoperative 1st week, 1st month, 3rd month, 6th month and 12th month mean total macular volume measurements were 7.03±0.2 mm³, 7.05±0.4 mm³, 7.0±0.6 mm³, 7.02±0.5 mm³ and 6.12±0.6 mm³, respectively. Mean central macular thickness measurements were 227.6±4.6 μm, 228.7±5.5 μm, 227.2±4.6 μm, 227.5±7.1 μm, 226.3±5.1μm respectively; mean parafoveal area thickness measurements were 290.2±3.7 μm, 289.9±7.8 μm, 288.7±6.3 μm, 288.8±4.7 μm, 288.6±8.3 μm respectively, mean perifoveal area thickness measurements were 261.1±4.2 μm, 261.4±1.9 μm, 260.4±3.6 μm, 259.8±2.7 μm, 259.3±4.7 μm respectively, and mean RNFL thickness measurements were 106.54±11.28 μm, 107.28±8.75 μm, 107.45±13.64 μm, 105.62±9.27 μm, 105.16±12.74 μm; respectively. Conclusion: No significant change was seen in macular thickness after penetrating keratoplasty. Although the macular thickness increases in the early postoperative stage, it decreases in time.Öğe Evaluation of metabolite changes in visual cortex in diabetic retinopathy by MR-Spectroscopy(Elsevier Science Inc, 2012) Ozsoy, Ercan; Doganay, Selim; Dogan, Metin; Alkan, Alpay; Firat, Penpe GulPurpose: To evaluate metabolite changes in the visual cortex of diabetic patients with nonproliferative or proliferative diabetic retinopathy by Magnetic Resonance Spectroscopy (MRS). Materials and Methods: 15 normal subjects (group 1), 15 patients with diabetes who did not have diabetic retinopathy (group 2), 15 patients with nonproliferative diabetic retinopathy (NPDR) (group 3), and 15 patients with proliferative diabetic retinopathy (PDR) (group 4) were included in the study. Furthermore, diabetic patients were divided into two groups according to HbA1c levels (Group A: 20 patients, HbA1c <8%; Group B: 20 patients, HbA1c >8%). In all cases' left visual cortex, amounts of N-acetyl-aspartate (NAA), choline (Cho), and creatine (Cr) were measured by MRS. NAA/Cr, Cho/Cr, and NAA/Cho ratios were calculated. Furthermore, all cases' complete blood count (CBC) and biochemical parameters were evaluated. Results: There was no statistically significant difference for NAA/Cr, Cho/Cr, and NAA/Cho ratios between groups 1. 2, 3, and 4 (P>0.05). However there was a statistically significant difference for NAA/Cr and NAA/Cho ratios between groups A and B (P<0.05). There was no statistically significant difference for Cho/Cr ratio between groups A and B (P>0.05). Conclusion: Although NAA/Cr and NAA/Cho ratios decrease in the visual cortex while diabetic retinopathy progresses, these decreases are not statistically significant. While HbA1c levels increase, the NAA concentration decreases in the visual cortex which indicates neuronal loss. The metabolite changes in the visual cortex are associated with acute events rather than chronic. (c) 2012 Elsevier Inc. All rights reserved.Öğe Evaluation of peripapillary retinal nerve fiber layer, macula and ganglion cell thickness in amblyopia using spectral optical coherence tomography(Ijo Press, 2013) Firat, Penpe Gul; Ozsoy, Ercan; Demirel, Soner; Cumurcu, Tongabay; Gunduz, AbuzerAIM: To investigate peripapillary retinal nerve fiber layer (RNFL), macula and ganglion cell layer thicknesses (GCC) in amblyopic eyes with spectral domain optical coherence tomography (SD-OCT). METHODS: Thirty six patients with a history of unilateral amblyopia and thirty two children who had emmetropia without amblyopia were included in this study. In this institutional study, 36 eyes of 36 patients with amblyopia (AE), 36 fellow eyes without amblyopia (FE), and 32 eyes of 32 normal subjects (NE) were included. RNFL, GCC and macular thickness measurements were performed with RS-3000 OCT Retina Scan (Nidek Inc CA. USA). RESULTS: The mean global thicknesses of the RNFL were 113.22 +/- 121.47, 111.57 +/- 18.25, 109.96 +/- 11.31 mu m in the AE, FE, and NE, respectively. There was no statistically significant difference for mean global RNFL thickness among the eyes (P=0.13). The mean thicknesses of the macula were 258.25 +/- 18.31, 258.75 +/- 19.54, 248.62 +/- 10.57 mu m in the AE, FE and NE, respectively. There was no statistically significant difference for thickness of macula among the eyes (P=0.06). The GCC was investigated into two parts: superior and inferior. The mean thicknesses of superior GCC were 102.57 +/- 113.32, 103.32 +/- 10.64, 100.52 +/- 15.88 mu m in the AE, FE, and NE, respectively. The mean thicknesses of inferior GCC were 103.82 +/- 112.60, 107.82 +/- 12.33, 105.86 +/- 10.79 mu m in the AE, FE and NE, respectively. There was no statistically significant difference for thickness of superior and inferior GCC between the eyes (P=0.63, P=0.46). CONCLUSION: The macular thicknesses of AE and FE were greater than the NE, although it was not statistically significant. Amblyopia does not seem to have a profound effect on the RNFL, macula and GCC.Öğe Evaluation of retinal and choroidal thickness in various age groups(2018) Celik, Fatih; Ulas, Fatih; Kaymaz, Abdulgani; Ozsoy, ErcanAim: To evaluate retinal and choroidal thickness of healthy individuals in various age groups with optical coherence tomography (OCT) and enhanced depth imaging (EDI)-OCT technique . Material and methods: Totally 149 healthy patients aged between 0 and 69 years from seven different decades were included in this study. The retinal and choroidal thickness of the central area (fovea) and of the nasal and temporal points at a distance of 1500 μm from this central point were measured in the right eye with an OCT device (Heidelberg, Germany) in all subjects. The subjects with any ocular or systemic pathology and the subjects with a spherical refractive error more than 3 D or a cylindrical refractive error more than 1 D were excluded. The measurements of right eyes of the subjects were used in the statistical analysis and the P value less than 0.01 was considered to be significant. Results: The mean retinal thickness measurements were 326.61±16.89 µm at the temporally, 218.72±19.06 µm centrally and 351.32±17.74 µm nasally, with no statistically significant difference between the age groups (p˃0.01). The mean choroidal thickness measurements were 299.01±72.38 µm temporally, 332.34±78.08 µm centrally and 258.30±71.80 µm nasally. There were statistically significant differences in central and temporal choroidal thickness between age groups (p˂0.01). Conclusion: A statistically significant decrease was present in the choroidal thickness but not in the retinal thickness with age.Öğe Evaluation of the equality of medial rectus advancement to medial rectus resection for consecutive exotropia(Cukurova Univ, Fac Medicine, 2022) Gunduz, Abuzer; Ozturk, Emrah; Ozsoy, ErcanPurpose: The aim of this study was to analyze the amount of medial rectus (MR) advancement in the treatment of consecutive exotropia by comparing it with the amount of MR resection in a sample of patients with constant exotropia and evaluate the effectiveness of MR advancement with lateral rectus (LR) recession in the management of consecutive exotropia. Materials and Methods: A retrospective chart review of patients who underwent unilateral MR strengthening with LR weakening due to consecutive or constant exotropia was performed. Patients with consecutive exotropia underwent MR advancement with LR recession, and those with constant exotropia underwent MR resection with LR recession. The surgical dosages were determined according to a standard table. A successful result was defined as alignment within 10 prism diopters of orthotropia. Results: A total of 36 patients fulfilled the inclusion criteria: 18 had consecutive exotropia and 18 had constant exotropia. Successful alignment was obtained in 83.3% of patients with consecutive exotropia and 88.9% of patients with constant exotropia. There was no difference between the amount of MR advancement performed in consecutive patients with exotropia and the amount of MR resection performed in patients with constant exotropia. Postoperatively, while consecutive exotropes with a poor result showed overcorrection, constant exotropes with a poor result showed undercorrection. Conclusion: This study suggests that there is no difference between the amount of previously recessed MR advancement and that of untouched MR resection. They also showed that MR advancement with LR recession is an effective means of correcting secondary exotropia.Öğe Infantile Esotropia: Clinical Features and Results of Bilateral Medial Rectus Recession(Galenos Publ House, 2023) Gunduz, Abuzer; Ozturk, Emrah; Ozsoy, Ercan; Gunturkun, Pelin NazliIntroduction: To define the characteristics of infantile esotropia and evaluate the results of bilateral medial rectus recession in infantile esotropia. Methods: A retrospective review was performed on medical charts of patients diagnosed with infantile esotropia. All patients underwent an ophthalmological examination to detect the conditions that accompany infantile esotropia. Patients with two years of age or older and without fixation preference or amblyopia underwent bilateral medial rectus recession. Results: There were a total of 117 patients with infantile esotropia patients. Infantile esotropia was accompanied by inferior oblique hyperfunction, fixation preference, cross-fixation, pseudoabduction deficit, pattern deviations, nystagmus, dissociated vertical deviation, convergence insufficiency, and abnormal head position. Approximately forty percent of the patients compatible with visual acuity measurements had amblyopia. Bilateral medial rectus recession decreased the mean esotropia from 43.1 +/- 15.3 to 7.8 +/- 12.8 prism diopters (PD) in 65 patients. Postoperatively, 41 patients had an ocular alignment within 10 PD of orthotropia, 22 patients showed undercorrection and 2 overcorrection. Conclusion: The characteristics of infantile esotropia in our study are substantially consistent with those of early reports, except for convergence insufficiency. This study also showed that bilateral medial rectus recession appears to have a high percentage of undercorrection in short-term postoperative follow-up in infantile esotropia.Öğe Inferior Oblique Muscle Overaction: Clinical Features and Surgical Management(Hindawi Ltd, 2019) Ozsoy, Ercan; Gunduz, Abuzer; Ozturk, EmrahPurpose. To further define the clinical features of patients with inferior oblique muscle overaction (IOOA) and evaluate the surgical results in a subgroup of these patients. Methods. The medical records of 173 patients who underwent inferior oblique muscle (IO) weakening surgery due to primary or secondary IOOA were retrospectively reviewed. The patients were assigned a surgical group based on severity of IOOA and presence of dissociated vertical deviation (DVD) or hypertropia. Patients with +1 or +2 IOOA underwent recession, patients with +3 or +4 IOOA underwent myectomy, and patients with any grade of IOOA and DVD or hypertropia underwent anterior transposition (AT) surgery. Results. A total of 286 eyes of 173 patients who underwent surgery due to IOOA were included in the study. IOOA was accompanied by esotropia, exotropia, abnormal head posture (AHP), pattern strabismus, convergence insufficiency, DVD, facial asymmetry, and nystagmus. The most common comorbid disorder was esotropia. The recession was used in 173 eyes, myectomy in 64, and AT in 49. Surgical success was obtained in 96.0% of eyes that underwent recession, in 98.4% of eyes that underwent myectomy, and in 93.9% of eyes that underwent AT. In the follow-up, IOOA occurred in the fellow eye in 36.1% of patients who underwent unilateral surgery. Conclusions. This study is a comprehensive report on the concomitants of the IOOA. Also, it showed that all of the three surgical procedures including recession, myectomy, and AT are effective in the surgical management of IOOA when performed in select patient groups.Öğe Is There Any Relation Between Pseudoexfoliation Syndrome and Alzheimer's Type Dementia?(Taylor & Francis Inc, 2013) Cumurcu, Tongabay; Dorak, Ferhat; Cumurcu, Birgul Elbozan; Erbay, Lale Gonenir; Ozsoy, ErcanPurpose: To investigate the frequency of Alzheimer-related dementia in patients with pseudoexfoliation syndrome (PEX). Methods: Sixty-seven patients with PEX and 67 age-, gender-, and educational-background-matched control subjects were compared for the presence of Alzheimer-related dementia according to DSM-IV-TR. The effects of cataract, glaucoma, additional ocular and systemic disease on the dementia incidence were also evaluated in patients with PEX and the control group. Results: The frequency of Alzheimer-related dementia was higher in patients with PEX (p = 0.0001). The frequency of dementia in patients who had cataract was higher than in patients without cataract (p = 0.003). There was also an association between additional ocular disease and dementia (p < 0.05). However, there was no association between systemic disease and dementia (p > 0.05). Furthermore, there was no difference for the frequency of dementia between patients who had glaucoma or not among patients with PEX (p = 0.953). Conclusion: The increased frequency of Alzheimer-related dementia in patients with PEX is important and a possible association between PEX and Alzheimer's disease could be present.Öğe Results of scleral fixated intraocular lens implantation(Inonu University Faculty of Medicine, Department of Ophthalmology, Malatya, Turkey, 2018) Ozsoy, Ercan; Duman, Behice Suheda; Gunduz, Abuzer; Cumurcu, TongabayAbstract: Aim: To evaluate the results of scleral fixated intraocular lenses (SFIOLs) implantation in eyes that had lost capsular support. Material and methods: Eyes of twenty patients who had lost their capsular support due to various causes included in this study. This study involved 5 females and 15 males. Eight eyes were included following complicated cataract surgeries, five eyes were patients in trauma, three eyes were with subluxated intraocular lens, three aphakic eyes which underwent congenital cataract surgeries and one eye that had beginning of bullous keratopathy due to anterior chamber lens were operated. The secondary SFIOLs implantation were performed in all eyes. Preoperative and postoperative best corrected visual acuities were compared. Results: The mean age of patients was 61.4±15.04 years. The mean follow-up time was 3.12±0.7 months. The best corrected mean preoperative and postoperative visual acuities of patients were found as 0.16±0.02 and 0.38±0.07; respectively, using the Snellen chart. In our study; in two patients corneal edema, in one patient pupillary irregularity and in one patient increased intraocular pressure were observed. There was a statistically significant difference between the mean preoperative and postoperative visual acuities of patients according to the Wilcoxon test (p=0.01). Conclusion: SFIOLs implantation have still maintained its importance for correction of aphakia in patients without adequate capsular support despite all new developments.Öğe Results of scleral fixated intraocular lens implantation(2018) Ozsoy, Ercan; Duman, Behice Suheda; Gunduz, Abuzer; Cumurcu, TongabayAim: To evaluate the results of scleral fixated intraocular lenses (SFIOLs) implantation in eyes that had lost capsular support. Material and methods: Eyes of twenty patients who had lost their capsular support due to various causes included in this study. This study involved 5 females and 15 males. Eight eyes were included following complicated cataract surgeries, five eyes were patients in trauma, three eyes were with subluxated intraocular lens, three aphakic eyes which underwent congenital cataract surgeries and one eye that had beginning of bullous keratopathy due to anterior chamber lens were operated. The secondary SFIOLs implantation were performed in all eyes. Preoperative and postoperative best corrected visual acuities were compared. Results: The mean age of patients was 61.4±15.04 years. The mean follow-up time was 3.12±0.7 months. The best corrected mean preoperative and postoperative visual acuities of patients were found as 0.16±0.02 and 0.38±0.07; respectively, using the Snellen chart. In our study; in two patients corneal edema, in one patient pupillary irregularity and in one patient increased intraocular pressure were observed. There was a statistically significant difference between the mean preoperative and postoperative visual acuities of patients according to the Wilcoxon test (p=0.01). Conclusion: SFIOLs implantation have still maintained its importance for correction of aphakia in patients without adequate capsular support despite all new developments.
