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    Cancer of Unknown Primary Presenting With a Giant Shoulder Mass in a Young Man: Prostate Adenocarcinoma
    (Kare Publ, 2018) Atilla, Fatos Dilan; Topaloglu, Omercan; Pala, Emel Ebru; Arslan, Cagatay
    Cancer of unknown primary (CUP) is a metastatic tumor for which a standardized diagnostic workup fails to identify the site of origin at the time of making the diagnosis. The most frequent primary origin site is the lung and pancreas (40%), and the second most frequent primary origin site is the gastrointestinal system. For male patients with CUP, serum prostate specific antigen (PSA) level and free PSA/total PSA ratio should be determined; if necessary, immunohistochemical staining for PSA and P504S should be performed from the metastatic mass. Young patients with CUP should be attentively evaluated to establish the diagnosis and start treatment. We report the case of a young man who presented with a giant shoulder mass of unknown primary site and was diagnosed as having prostate adenocarcinoma.
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    Cancer of unknown primary presenting with a giant shoulder mass in a young man: prostateadenocarcinoma
    (Kare publ, concord ıstanbul, dumlupınar mah, cıhan sk no 15, b blok 162 kadıkoy, ıstanbul, 00000, turkey, 2018) Atilla, Fatos Dilan; Topaloglu, Omercan; Pala, Emel Ebru; Arslan, Cagatay
    Cancer of unknown primary (CUP) is a metastatic tumor for which a standardized diagnostic workup fails to identify the site of origin at the time of making the diagnosis. The most frequent primary origin site is the lung and pancreas (40%), and the second most frequent primary origin site is the gastrointestinal system. For male patients with CUP, serum prostate specific antigen (PSA) level and free PSA/total PSA ratio should be determined; if necessary, immunohistochemical staining for PSA and P504S should be performed from the metastatic mass. Young patients with CUP should be attentively evaluated to establish the diagnosis and start treatment. We report the case of a young man who presented with a giant shoulder mass of unknown primary site and was diagnosed as having prostate adenocarcinoma.
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    Oldukça sık görülen benign bir tümörün nadir lokalizasyonu
    (İnönü Üniversitesi Tıp Fakültesi Dergisi, 2015) Keskin, Elif Usturalı; Pala, Emel Ebru; Çakır, Ebru; Taner, Cüneyt Eftal; Sarıkaya, Serhat; Keskin, Fatih
    Lipoma is the most common benign mesenchymal soft tissue tumor. It consists of mature adipocytes, usually located in subcutaneus tissues and occurs more frequently in obese patients. Subcutaneous lipoma is usually found in the head and neck regions. Vulvar lipoma is extremely rare. A 72-year-old obese woman was admitted to our hospital with a painless vulvar mass. Physical examination revealed a single, soft, mobile mass in the right vulvar area that measured about 15 cm in its widest dimensions. The excised specimen measured 13 cm and had a yellow cut surface, surrounded by a fibrous capsule. Microscopic examination confirmed the diagnosis of lipoma. Vulvar lipoma has benign clinical course. If this lesion is untreated, it may grow large. To exclude the possibility of malignancy, surgical excision must be performed. This case is one of the biggest vulvar lipoma cases reported in the Anglophone medical literature.
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    An Uncommon Presentation of a Common Benign Tumour
    (2015) Keskin Usturalı, Elif; Pala, Emel Ebru; Taner, Cüneyt Eftal; Çakır, Ebru; Sarıkaya, Serhat; Keskin, Fatih
    Abstract:Lipom en yaygın benign mezenkimal yumuşak doku tümörüdür. Matür adipositlerden oluşur, daha sık obez hastalarda subkutan dokuda görülür. Subkutan lipom genellikle baş boyun bölgesi yerleşimlidir. Vulvar lipom oldukça nadirdir. 72 yaşında obez kadın hasta vulvada ağrısız şişlik şikayeti ile başvurdu. Fizik muayenede sağ vulvada yaklaşık 15 cm çaplı tek, yumuşak, mobil kitle palpe edildi. Eksize edilen materyal 13 cm çaplı fibröz kapsülle örtülü matür yağ dokusu görünümündeydi. Mikroskobik inceleme sonucu lipom tanısı konuldu. Vulvar lipom benign klinik gidiş gösterir. Tedavi edilmezse büyük boyuta ulaşabilir. Malignite olasılığını dışlamak için tedavi komplet cerrahi eksizyon olmalıdır. Bu olgu İngilizce literatürde rapor edilmiş en büyük vulvar lipomlardan biridir.