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    Management of thrombosis in a pediatric renal transplant patient with factor vii deficiency a dilemma concerning recombinant factor VIIa
    (BETA Medical Publishers Ltd, 2020) Yalcin M.; Simsek A.; Tabel Y.; Dogan S.M.; Piskin T.
    Hemorrhagic complications in surgical patients with congenital factor VII deficiency are a major concern. Replacement therapy is required, in which recombinant factor VIIa is the first treatment choice, by virtue of its higher efficacy and no risk of infection. Because of the risk of vascular thrombosis, recombinant factor VIIa treatment may result in catastrophic outcomes, includ-ing graft loss in transplant patients. We present the case of a 7-year-old male who underwent renal transplantation and who developed renal thrombosis after recombinant factor VIIa substution therapy for factor VII deficiency. © 2020, BETA Medical Publishers Ltd. All rights reserved.