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    Assessing the validity and reliability of the Turkish version of the Trunk Impairment Scale in stroke patients
    (Kare Publ, 2019) Sag, Sinem; Buyukavci, Raikan; Sahin, Fusun; Sag, Mustafa Serdar; Dogu, Beril; Kuran, Banu
    OBJECTIVE: To determine the validity and reliability of the Turkish version of the Trunk impairment scale (TIS), used in the evaluation of somatic, motor, and coordination disturbances in stroke patients, and provide a culturally adapted version for use in the Turkish population. METHODS: A total of 80 patients who were either hospitalized at our facility and rehabilitated for stroke or admitted at our outpatient clinics were included in this study. Reliability was evaluated by the internal consistency (Cronbach a) and test reproducibility [intra-class correlation coefficient (ICCC)] methods, and validity was evaluated by the correlation between subgroups and the total scores of the TIS and Berg Balance Scale (BBS), Brunnstrom phases, Barthel index (BI), Rivermead mobility index (RMI), and Short Form-36 (SF-36) scores. RESULTS: The mean age of the patients was 63.00 +/- 12.1 years. Out of a total of 80 subjects, 34 were female and 46 were male. The reliability of the scale was evaluated by the internal consistency, inter-and intra-observer reliability, and test reproducibility. The findings showed that the Turkish form of the scale was reliable at a good level. The test values were as follows; Cronbach a: >0.70, ICCC: 0.969-1, subgroups and total score comparison: 0. The correlation between TIS and BBS was considerably high in the validity analysis (p<0.001). Further, significant associations among the BI, RMI, KF-36, Brunnstrom, and TIS scores were found (p<0.001), which indicate the structural validity of this scale. CONCLUSION: TIS is a scale used in measuring the motor derangement that develops after a stroke. It has sufficient reliability, internal consistency, and validity for use in clinical practice and stroke investigations. Our study has shown that TIS used for the evaluation of body balance is valid and reliable for the Turkish population.
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    Comparison of blood platelet distribution width and neutrophil-lymphocyte ratio in patients with different grades of knee osteoarthritis
    (Ios Press, 2018) Buyukavci, Raikan; Akturk, Semra; Sag, Sinem
    OBJECTIVE: The aim of this study was to compare platelet distribution width (PDW) and neutrophil to lymphocyte ratio (NLR) values in mild-to-moderate and severe knee osteoarthritis (OA). METHODS: This was a retrospective study of patients with knee OA according to the Kellgren-Lawrence (KL) grading system. Of 465 patients, 231 were excluded (62 due to not meeting the inclusion criteria and 169 due to the lack of simultaneous haemogram and radiographic evaluations). Demographic characteristics and PDW and NLR values were recorded. The patients were then divided into two groups: KL grade 1-3 (mild-to-moderate OA) and KL grade 4 (severe OA). RESULTS: In severe knee OA patients, blood PDW (13.44 +/- 2.58, p = 0.01) and NLR values (2.16 +/- 0.84, p = 0.04) were elevated as compared with those in mild-to-moderate knee OA patients. Blood PDW and NLR values of >= 12.5 and >= 2.1, respectively, were taken as cut-offs based on a receiver operating characteristics (ROC) curve analysis. In the ROC curve analysis, blood NLR >= 2.1 had 60% sensitivity and 64.8% specificity, and PDW >= 12.5 had 61% sensitivity and 58% specificity in predicting severe knee OA. In a univariate analysis, age (p < 0.001), PDW >= 12.5 (p = 0.029) and blood NLR >= 2.1 (p = 0.030) emerged as significant predictors of the severe knee OA. CONCLUSION: The results suggested that the blood PDW and NLR are novel inflammatory markers that can predict the radiographic severity of knee OA in clinical practice.
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    Comparison of blood platelet distribution width and neutrophil-lymphocyte ratio in patients withdifferent grades of knee osteoarthritis
    (Ios press, nıeuwe hemweg 6b, 1013 bg amsterdam, netherlands, 2018) Buyukavci, Raikan; Akturk, Semra; Sag, Sinem
    OBJECTIVE: The aim of this study was to compare platelet distribution width (PDW) and neutrophil to lymphocyte ratio (NLR) values in mild-to-moderate and severe knee osteoarthritis (OA). METHODS: This was a retrospective study of patients with knee OA according to the Kellgren-Lawrence (KL) grading system. Of 465 patients, 231 were excluded (62 due to not meeting the inclusion criteria and 169 due to the lack of simultaneous haemogram and radiographic evaluations). Demographic characteristics and PDW and NLR values were recorded. The patients were then divided into two groups: KL grade 1-3 (mild-to-moderate OA) and KL grade 4 (severe OA). RESULTS: In severe knee OA patients, blood PDW (13.44 +/- 2.58, p = 0.01) and NLR values (2.16 +/- 0.84, p = 0.04) were elevated as compared with those in mild-to-moderate knee OA patients. Blood PDW and NLR values of >= 12.5 and >= 2.1, respectively, were taken as cut-offs based on a receiver operating characteristics (ROC) curve analysis. In the ROC curve analysis, blood NLR >= 2.1 had 60% sensitivity and 64.8% specificity, and PDW >= 12.5 had 61% sensitivity and 58% specificity in predicting severe knee OA. In a univariate analysis, age (p < 0.001), PDW >= 12.5 (p = 0.029) and blood NLR >= 2.1 (p = 0.030) emerged as significant predictors of the severe knee OA. CONCLUSION: The results suggested that the blood PDW and NLR are novel inflammatory markers that can predict the radiographic severity of knee OA in clinical practice.
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    Evaluating loss of productivity in patients with rheumatoid arthritis and its relationship to clinical parameters
    (2018) Sag, Sinem; Nas, Kemal; Sag, Mustafa Serdar; Tekeoglu, Ibrahim; Kamanli, Ayhan; Aydeniz, Aysenur
    Aim: This study investigated loss of productivity of working women and housewives with rheumatoid arthritis (RA) and analyzed the correlation of this loss with disease activity parameters and health-related quality of life. Material and Methods: The study enrolled consecutive patients presenting to rheumatology outpatient clinic between April 2016 and September 2016 who met the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) RA classification criteria. Disease activity with the Disease Activity Score (DAS-28) as it pertains to C-reactive protein (CRP), functional status with the Duruöz hand index, activities of daily life with the Health Assessment Questionnaire (HAQ), and health-related quality of life with the short-form 36 (SF-36) questionnaire. Results: This study included 82 RA patients (56 women, 26 men) who were followed in our rheumatology outpatient clinic, and 29 healthy controls (24 women, 5 men) who were patient accompanists and patient visitors. We found no difference between housewives and employed women with RA in terms of disease activity, productivity in daily activities, anxiety, or depression, but patients with RA had higher pain, fatigue, and anxiety scores than healthy controls. Loss of productivity in daily activities was found to be correlated with disease activity and fatigue. Conclusions: In conclusion, disease activity, quality of life, and functional status are equally important in RA patients who work as housewives or in the workforce. Emotional status has an impact, especially on increasing productivity and participation in daily life, and doctors should also examine their patients from this perspective