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  • Küçük Resim
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    Cerebral venous sinus thrombosis in children: Clinical, imaging, laboratory findings and evaluation of relation to the platelet indices
    (2019) Saglam, Dilek
    Aim: The aim of this study is to present clinical, imaging and laboratory findings of pediatric cerebral venous sinus thrombosis (CVST), and to evaluate any relationship between the platelet indices and CVST in children.Material and Methods: Clinical, laboratory and imaging findings of fifteen children with detected CVST on MRI examinations were recorded retrospectively. Fifteen controls were included in the study. All patients and controls were evaluated and platelet indices including; MPV, PDW, PC and MPV/plt ratio were compared.Results: There was no difference in age and gender distribution between patients and controls. The most common symptom in patients with CVST was headache and fever. Platelet count, PDW, MPV and MPV/plt ratio were slightly higher in controls, however there was no significant difference between two groups (p=0.2, p=0.486, p=0.47, p= 0.595, respectively). Prothrombotic state was found in 33% of our patients and all had increased homocysteine levels. The most common localization of thrombosis was transverse sinus with 50% involvement. Conclusion: This study presented clinical, MRI and laboratory findings of children with CVST and showed no difference in PC, MPV, PDW and MPV/plt ratio between patients and controls. Platelet indices may not be used to support the diagnosis of CVST in children.
  • Küçük Resim Yok
    Öğe
    The role of ARFI elastography to evaluate microstructrual changes of patients with testicular microlithiasis
    (Sage Publications Ltd, 2018) Aslan, Serdar; Bilgici, Meltem Ceyhan; Saglam, Dilek; Ozturk, Mesut
    Background: Testicular microlithiasis (TML) is thought to cause microstructural changes in the parenchyma of the testis, but it is difficult to demonstrate this by ultrasonography. It may be possible to evaluate microstructural changes in the testis by Acoustic Radiation Force Impulse (ARFI) elastography, which measures tissue stiffness. Purpose: To assess the tissue stiffness of testicles of children with TML and to compare them with the healthy control group. Material and Methods: Between November 2015 and May 2016, 25 pediatric patients with TML and 24 healthy children were enrolled in the study (mean age for TML and control group 6.7 +/- 3.17 and 7.9 +/- 4.18 years, respectively). Testicular volumes and mean shear wave velocity (SWV) values were calculated and compared with each other in both groups. Results: There was no significant difference in average testicular volumes between the TML group and the control group (1.14 cm(3), 1.21 cm(3), respectively; P = 0.986). Mean SWV of the testicles with TML and normal testicles with control group was 1.18 +/- 0.22 cm/s and 0.88 +/- 0.11 cm/s, respectively. The SWV of the testicles with TML was higher than the normal testicles and this was statistically significant (P < 0.001). Conclusion: This study has shown that tissue stiffness in patients with TML is increased compared to the normal population. ARFI elastography helps the early detection of microstructural changes in TML and can be used for screening and follow-up.