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Öğe Akne Vulgaris ve Rozase Hastalarında Deri Sebum, pH ve Nem Değerlerinin Demodeks Enfestasyonuna Etkisi(Türkiye Parazitoloji Dergisi, 2017) Turan, Nergiz; Kapıcıoğlu, Yelda; Saraç, GülbaharAbstract: Objective: Acne vulgaris is an inflammatory disease involving the pilosebaceous unit. Rosacea is a chronic inflammatory skin disease that affects the face in particular. This study aimed to determine if skin sebum, pH, and moisture affect the number of Demodex spp. in acne vulgaris and rosacea patients. Methods: This study focused on 30 patients each with acne vulgaris and rosacea. As a control group, 60 healthy individuals were included. Results: In acne vulgaris patients, when compared to those with Demodex mite more than 5 /cm 2 in each area, less than 5/cm 2 were found to be oily, acidic, dry or very dry. However, there was no significant difference in moisture value. In patients with rosacea, the skin was acidic and dry in patients those with more than 5/cm 2 Demodex mites when compared to those with demodex mite less than 5 /cm 2 in patients in each of the right cheek and nose areas. There was no difference in skin oil level. Conclusion: The oily, acidic, dry, and very dry skin of the acne vulgaris patients and the oily, acidic, and very dry skin of the rosacea patients are factors facilitating the development of Demodex ssp.Öğe Autologous mesenteric vein and peritoneum for repair of portal vein and hepatic artery injuries accompanying bile duct injury following laparoscopic cholecystectomy(2018) Kapıcıoğlu, Yelda; Cenk, Hülya; Şener, Serpil; Mantar, İrem; Saraç, GülbaharAbstract: Biliary tract injuries are still the most hazardous complications of laparoscopic cholecystectomy. Concomi-tant vascular injuries make them further more complicated and complex surgical interventions including autologous grafting can be required. We presented a 32-year-old female referred us with combined bile duct, portal vein and hepatic artery injuries occurred during laparascopic surgery. The repairs of hepatic artery and portal vein were achieved by autologous inferior mesenteric vein and peritoneum grafts, respectively. Bile duct reconstruction was done by Roux-en-Y hepaticojejunostomy. Postoperative course was unevent-ful and she was asymptomatic following 16 months follow-up. Autologous vein and peritoneal grafts can be used for repair of vascular injuries of laparascopic cholecystectomy.Öğe Bullous dermatosis in the southeastern of Turkey: A study of125 cases(2022) Mantar, Irem; Saraç, Gülbahar; Karatoprak, Hacer Vural; Cenk, HülyaAim: Autoimmune bullous diseases occur when antibodies against proteins such as desmosomes and hemidesmosomes cause separation in the skin. Detailed epidemiological studies examining these diseases are limited in our country. We aim to contribute to the demographic, clinical, and treatment data on bullous diseases from an important geographic region of our country. Materials and Methods: The data of 125 cases who were followed up with a diagnosis of bullous disease between 2006 and 2019 were evaluated retrospectively. Socio-demographic characteristics, diagnoses, age and duration of disease onset, clinical findings, accompanying systemic diseases, treatments given, and side effects related to treatment were recorded. Results: 57.6% of the patients (72 people) were diagnosed as pemphigus, 31.2% (39 people) bullous pemphigoid (BP), 8% (10 people) dermatitis herpetiformis (DH), 3.2% (4 people) linear Ig A dermatosis ( LAD). BP patients were found to be significantly older than the other patients (p = 0.002). While pemphigus, BP, and LAD were more common in women, 70% of DH patients were men. Malignancy was detected in 2.8% of pemphigus patients and 5.1% of BP patients. Accompanying autoimmune disease was found in 9.7% of pemphigus patients, 17.9% of BP patients, and 20% of DH patients. The only systemic steroid was used in 20.8% of pemphigus patients, and azathioprine as a conventional agent was used in 76.4% with systemic steroid. Rituximab was started in patients who did not respond to therapy. The systemic steroid was used in 35.9% of BP patients, and azathioprine with systemic steroid was used in 43.6% of BP patients. Doxycycline was added to the treatment in 41% of the patients. Rituximab was used in 5 (12.8%) patients. Conclusion: Since our study is the first data obtained on bullous diseases from the southeastern Anatolia region, it is useful for the literature in terms of providing a basis for future studies. İremÖğe A case of confluent and reticular papillomatosis responding to systemic isotretinoin treatment(2017) Polat, Ayşegül; Şener, Serpil; Şahin, Nurhan; Saraç, GülbaharAbstract: Confluent and reticular papillomatosis is a rarely seen dermatosis. It is characterised by the joining together of brown, hyperkeratotic papules and plaques in a reticular pattern. It is generally seen in females in the 10-35 years age range and the etiology is not fully known. The case is here presented of a 40year old female, diagnosed with confluent and reticular papillomatosis who responded well to isotretinoin treatmentÖğe A case with pyoderma gangrenosum, after an abdominal surgery(2019) Saraç, Gülbahar; Mantar, Irem; Cenk, Hülya; Sarac, MehmetAbstract: Pyoderma gangrenosum (PG) is a pathergy positive, ulcerative neutrophilic dermatosis. Pathergy phenomenon is described as a sterile pustule and an ulcer development after minor skin traumas like a bump or bruise, or needlestick injury. In the literature, there are PG cases associated with the pathergy phenomenon on the post-surgical scar tissue. It presents as a necrotic and an ulcerative lesion clinically and, debridement is performed mostly with wrong pre-diagnoses. Debridement makes the lesion get wider and the morbidity increase. There are some PG case reports in the literature which were ended up with amputation due to debridement of a lesion which was an overlooked PG. Herein, we present a case with a giant abdominal pyoderma gangrenosum developed after a surgery in the abdominal drainage site and has reached to 30 cm size after debridement.Öğe Darier hastalığında fatal herpes simpleks virüs enfeksiyonu(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2015) Altunışık, Nihal; Saraç, Gülbahar; Demirdağ, Hatice Gamze; Şenol, MustafaDarier disease is an autosomal dominant disorder characterized by small, hyperkeratotic papules localised on the trunk especially in the seborrheic regions. Vegetation and infections in the intertriginous areas are common in this disease while treatment is not usually satisfying. While the urea or lactic acid containing moisturizers, topical steroids, and topical retinoids are used in mild cases, systemic retinoids are preferred in severe cases. Kaposi varicelliform eruption caused by herpes simplex virus is rare but a well-defined complication. Clinical findings of this viral infection, which are usually uncommon, may delay diagnosis and treatment. Here, we report the case of a patient with Darier’s disease treated with corticosteroids who later developed fatal herpes simplex virus infection despite the aciclovir therapy.Öğe Determination of sunscreen and cosmetic product use awareness in adolescents(2019) Saraç, Gülbahar; Tetik, Burcu Kayhan; Şener, Serpil; Mantar, İrem; Kapıcıoğlu, YeldaAbstract: Aim: Using an appropriate sunscreen is very important because the role of sun rays in development of skin cancer is well known. Besides, the recent increase in the use of cosmetics among adolescents is noteworthy. In this study, we aimed to determine the frequency of using cosmetics and the level of awareness of harmful effects of the sun, in adolescents. Material and Methods: In this cross-sectional descriptive study, a questionnaire consisted of 25 questions was applied, on voluntary basis, in middle schools. Results: A total of 607 students participated in the study; 434 participants were female students (71.5%), 173 were male students (28.5%) and the average age was 17 years. The question “Do you think it is necessary to protect from the sun?” is answered as “yes” by 361 of the female students (81.1%) and 109 of the male students (62.3%). The question “Do you use sunscreen?” is answered as “Yes” by 33.3% of all participants. Conclusion: In our study, we found that adolescents had a good understanding of the harmful effects of sun, but in contrast to this, we found that the use of sunscreen products was at very low levels. We think that education and methods for building awareness in this regard will be effective.Öğe Evaluation of changes in neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in patients with vitiligo(2019) Saraç, Gülbahar; Altunışık, Nihal; Şener, Serpil; Hakverdi, GüldenAbstract: Aim: Vitiligo is an acquired disease with loss of melanocytes, etiology of which is unclear. The aim of this study is to determine the role of systemic inflammation in vitiligo by measuring the Neutrophil-Lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) markers included in routine hemogram test, in patients with vitiligo. Material and Methods: The study was carried out by reviewing the data of patients who applied to İnönü University Faculty of Medicine Dermatology Polyclinic and diagnosed with vitiligo after Wood’s lamp examination, between July 2012 and February 2018. The study was performed retrospectively by reviewing patient files and ethics committee approval was not obtained. Results: A total of 170 individuals including 79 vitiligo patients and 91 healthy individuals were included in the study. When the vitiligo patients and healthy control group were compared in terms of routine hemogram parameters, statistically significant differences were found in terms of erythrocyte distribution width (RDW), but there were no statistically significant differences in terms of NLR, PLR, lymphocyte, neutrophil, platelets and White bloodcell (WBC) counts. Conclusion: In our study, only RDW value was found to be higher in patients with vitiligo compared to healthy controls, and no difference was found in other parameters indicating systemic inflammation.Öğe EVALUATION OF SUNBATHING AND PROTECTION AWARENESS ACCORDING TO THE SOCIODEMOGRAPHIC CHARACTERISTICS OF INDIVIDUALS AGED ABOVE 65 YEARS(Türk Geriatri Dergisi, 2018) Tetik, Burcu Kayhan; Saraç, Gülbahar; Mete, Burak; Şener, Serpil; Kalem, Hülya; Kılıç, EvrimÖz: Introduction: Because excessive exposure to solar radiation contributes to the aging of skin and the risk of skin cancer, protection from sunlight has become an important public health problem. This study aims to assess the knowledge level of individuals aged >65 years regarding sun exposure and their current use of sunscreen products. Materials and Method: A questionnaire consisting of 22 questions was prepared to measure sun protection awareness and use of sunscreen products by individuals aged >65 years. Between July and August 2017, the questionnaire was administered to 603 patients who presented to outpatient clinics. The data were analyzed using SPSS 22 software; a p-value of ?0.05 was considered significant. Results: The average age of the 603 participants was 67.8 years; 202 (33.5%) of them stated that they generally remained in the sun for 4–6 h, and 518 (86.3%) indicated that they had not received any information about sun protection. Conclusion: We found that individuals aged ?65 years had insufficient knowledge of the dangers of excessive sun exposure and were not protected from it. In order to reduce the risk of skin cancer in Turkey, education regarding lifestyle modification, sun protection, and use of sunscreen should be provided and relevant health policies should be formulated for these trainings to become a part of lifestyle there.Öğe Evaluatıon of sunbathıng and protectıon awareness accordıng to thesocıodemographıc characterıstıcs of ındıvıduals aged above 65 years(GUNES KITABEVI LTD STI, M RAUF INAN SOK NO 3, ANKARA, SIHHIYE 06410, TURKEY, 2018) Kayhan Tetik, Burcu; Saraç, Gülbahar; Mete, Burak; Şener, Serpil; Kalem, Hülya; Kılıç, EvrimIntroduction: Because excessive exposure to solar radiation contributes to the aging of skin and the risk of skin cancer, protection from sunlight has become an important public health problem. This study aims to assess the knowledge level of individuals aged > 65 years regarding sun exposure and their current use of sunscreen products. Materials and Method: A questionnaire consisting of 22 questions was prepared to measure sun protection awareness and use of sunscreen products by individuals aged > 65 years. Between July and August 2017, the questionnaire was administered to 603 patients who presented to outpatient clinics. The data were analyzed using SPSS 22 software; a p-value of. < 0.05 was considered significant. Results: The average age of the 603 participants was 67.8 years; 202 (33.5%) of them stated that they generally remained in the sun for 4-6 h, and 518 (86.3%) indicated that they had not received any information about sun protection. Conclusion: We found that individuals aged >= 65 years had insufficient knowledge of the dangers of excessive sun exposure and were not protected from it. In order to reduce the risk of skin cancer in Turkey, education regarding lifestyle modification, sun protection, and use of sunscreen should be provided and relevant health policies should be formulated for these trainings to become a part of lifestyle there.Öğe Fatal Herpes Simplex Virus Infection in Darier's Disease(2015) Şenol, Mustafa; Saraç, Gülbahar; Demirdağ, Hatice Gamze; Altunışık, NihalDarier Hastalığı, otozomal dominant kalıtımla geçen, klinik olarak gövdede ve özellikle seboreik alanlarda lokalize, küçük, hiperkeratotik papüllerle karakterize bir hastalıktır. Hastalıkta intertriginöz alanlarda vejetasyon ve infeksiyonlar sıktır. Tedavisi genellikle tatmin edici değildir. Hafif olgularda üre veya laktik asit içeren nemlendiriciler, topikal steroidler, topikal retinoidler kullanılırken, şiddetli olgularda sistemik retinoidler tercih edilir. Herpes simpleks virüsünün neden olduğu Kaposinin variselliform erüpsiyonu hastalığın nadir görülen fakat iyi tanımlanmış bir komplikasyonudur. Bu viral enfeksiyonun alışılmışın dışındaki klinik bulguları, sıklıkla tanıda ve tedavinin verilmesinde gecikmelere neden olabilir. Burada kortikosteroid tedavisi alan bir Darier hastasında takipleri esnasında gelişen ve asiklovir tedavisine rağmen fatal seyreden, herpes simpleks virüs enfeksiyonu sunulmaktadır.Öğe Fenitoin Kullanımı Sonrası Gelişen DRESS Sendromu: Olgu Sunumu(2017) Tetik, Bora; Oğuzoğlu, Serdar Ali; Kayhan Tetik, Burcu; Saraç, GülbaharÖz: DRESS Sendromu ateş, cilt döküntüsü, iç organ tutulumu ve hematolojik anormalliklerle karakterize akut başlangıçlı, hayatı tehdit eden, nadir görülen, ilaca bağlı bir aşırı duyarlılık reaksiyonudur. En sık nedeni aromatik antikonvülzan kullanma sonrası görülmektedir. Bu olguda fenitoin kullanımı sonrasında ikinci haftada ateş yüksekliği ve cilt döküntüleri başlayan kırk dört yaşında bir erkek hasta sunulmuştur. Olgu, fenitoin tedavisinin kesilmesi sonrasında sistemik kortikosteroid ve destek tedavisi ile başarılı bir şekilde tedavi edilebilmiştir. Birinci basamakta aile hekimi, hastalarının akut ve kronik sağlık sorunlarını aynı anda yönetebilmelidir. Olgumuzda olduğu gibi akut başlangıçlı ateşe yaklaşımda bir aile hekimi hastasını iyi yönetebilmeli ve beraberinde cilt döküntüleri de gördüğünde kullandığı ilaçları da sorgulayarak DRESS Sendromunu akla getirmelidir.Öğe Foto Dağılım Gösteren Yaygın Granüloma Annülare Olgusu(Türk Dermatoloji Dergisi, 2017) Polat, Ayşegül; Saraç, GülbaharÖz: Granüloma annülare, dermis ve subkutan dokunun nispeten sık rastlanan idiyopatik bir hastalığıdır. Her ırk ve yaşta gözlenebilir, fakat kadınları daha sık etkiler (2: 1). Yaygın granüloma annülare, diffüz fakat simetrik yerleşimli, 10'dan fazla sayıda ve sıklıkla yüzlerce lezyondan oluşan, papüler veya annüler döküntüler şeklinde ortaya çıkar. Literatürde, fotosensitif dağılım gösteren yaygın granüloma annülare olgularının nadir olması nedeniyle 49 yaşındaki kadın bir hastanın boynunda, kolların ekstansör ve ellerin dorsal yüzlerinde, fotosensitif dağılıma uyan, topikal ve intralezyoner steroid tedavisine iyi yanıt veren jeneralize bir granüloma annülare olgusu sunulmaktadır.Öğe Hemostatik ajan Ankaferdin yara iyile emostatik ajan Ankaferdin yara iyileşmesinde mesinde rol alan büyüme faktörleri ve ol alan büyüme faktörleri ve hidroksiprolin üzerine etkisi(Astım Allerji İmmünoloji, 2015) Sezgin, Sevgi; Saraç, Gülbahar; Türköz, Yusuf; Şenol, MustafaÖz: Giriş: Yara iyileşmesinde, iyileşmede rol alan faktörleri (infl amatuvar hücreler, trombositler, mediyatörler, hücre dışı matriks vb.) etkileyerek, bu fazlara ait süreleri kısaltmak ve ideal skar oluşumunu sağlamak amacıyla pek çok topikal ve sistemik ajan kullanılmaktadır. Ankaferd, geleneksel olarak Türk tıbbında kullanılan beş bitkisel içeriğin çeşitli oranlarda karıştırılarak hazırlanan ve hemostatik ajan olarak kullanılan bir ekstraktır. Çalışmamızda Ankaferd in yara iyileşmesi üzerine olan etkileri incelendi. Gereç ve Yöntem: Bu amaçla, her biri dokuz denekten oluşan dört gruba ayrılmış 36 ratın sırt bölgesinde 8 mm lik punch biyopsi ile yaralar açıldı. Kontrol grubu olan D grubunda tedavi uygulanmazken, A grubuna topikal olarak günde iki defa Ankaferd, B grubuna günde iki defa gümüş sülfadiazin ve C grubuna günde iki defa aktif madde içermeyen baz krem uygulandı. Denekler makroskopik olarak 15 gün boyunca takip edildi ve 0, 3, 7 ve 15. günlerde hidroksiprolin, epidermal büyüme faktörü (EGF), vasküler endotelyal büyüme faktörü (VEGF) ve trombosit kaynaklı büyüme faktörü (PDGF) düzeylerine bakıldı. Sonuç: Gruplar arasında, EGF ve PDGF düzeyleri açısından anlamlı bir fark yoktu. Büyüme faktörlerinden sadece VEGF düzeylerinde gümüş sülfadiazin uygulanan grupta anlamlı şekilde bir düşüklük saptandı. Gümüş sülfadiazin ve Ankaferd uygulanan gruplarda yara iyileşme sürecinin hızlı olduğu tespit edildi. Bu gruplarda hidroksiprolin düzeyleri arasında anlamlı fark olmayıp, kontrol grubunda ise hidroksiprolin düzeyi istatistiksel olarak anlamlı yüksek bulundu. Sonuç olarak, Ankaferd in kontrol ve baz krem kullanılan gruba kıyasla, gümüş sülfadiazin uygulanan gruba yakın şekilde makroskopik bulgular açısından, iyileşme sürecini hızlandırdığı tespit edildiÖğe Kahramanmaraş Sütçü İmam Üniversitesi Dermatoloji Kliniğine Kutanöz Leishmaniasis Tanısı ile Kabul Edilen Hastaların Değerlendirilmesi(2017) Şener, Serpil; Karaman, Ülkü; Hakverdi, Gülden; Saraç, Gülbahar; kayhan tetik, BurcuÖz: Amaç: Leişmanyazis hücre içi protozoan parazitlerden kaynaklanan, farklı klinik formlardaki bir hastalık grubudur. Leişmanya türleri kutanöz, mukokutanöz ve visseral formlar olmak üzere 3 esas klinik forma yol açarlar. Türkiye'de visseral ve kutanöz leişmanya formları gözlenir. Bu çalışmanın amacı, Kliniğimize müracaat eden Kutanöz leişmanya (KL) vakalarını incelemek ve bu bölgede hastalığın önlenmesine katkı sağlamaktır. Yöntem: Çalışmada 2009 yılında Kliniğimize müracaat eden 20 Kutanöz leişmanya vakası incelendi. KL tanısı deri biyopsisi veya smear ile konuldu. Hastaların tedavilerinde intralezyonel meglumin antimonat uygulandı. Bulgular: 20 vakanın 12' si bayan 8'i erkek ortalama yaşları 20±15.43 yıl idi. Sürüntü ve biyopsi sonuçlarına göre 13 vakada KL pozitif bulundu. Sonuç: Bu çalışma bölgedeki KL durumunu tanımlayarak; müdahale yöntemlerini, halk sağlığı eğitimin ve kişisel koruyucu önlemlerin planlanmasına katkıda bulunabileceği düşünülmektedir.Öğe Lipoid proteinosis and epilepsy: Molecular analysis(2019) Tecellioğlu, Mehmet; Kamışlı, Özden; Acar, Ceren; Mergen, Hatice; Sözen, Mustafa Mert; Karaduman, Tuğçe; Saraç, Gülbahar; Erbay, Mehmet FatihAbstract: Aim: Lipoid proteinosis (LP) is also known as Urbach-Wiethe disease which is a rare autosomal recessive disorder characterized by intracellular accumulation of hyaline material in skin and mucosae. LP has typical neurological, dermatological and radiological findings. The pathogenesis of disease is unknown. In literature several cases have been reported up to date. Mutations in extracellular matrix protein 1 (ECM1) gene have been found to cause the disease. We evaluated the molecular features of a family diagnosed with LP and evaluate the known and novel mutations of LP. Material and Methods: Genomic DNA was extracted from peripheral blood of the patients and family members including clinically normal parents and two siblings of the two affected subjects by using a commercial DNA extraction kit. Polymerase chain reaction was performed for all 10 exons of ECM1 gene by using the primers defined. Results: All of the exons of the ECM1 gene were sequenced and this revealed a 2-bp deletion in exon 7 of the ECM1 gene in both patients and both parents. Patients have the homozygous 2-bp deletions (c735del TG) and the parents and two healthy siblings showed heterozygous 2-bp deletion. Conclusions: Our patients found to be homozygous for the deletion in ECM1 gene. In order to understand the molecular pathology of the disease in detail, further functional analysis of the mutations should be performed.Öğe Maksiller dermatomu tutan bir ramsay-hunt sendromu olgusu(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2014) Saraç, Gülbahar; Şenol, Mustafa; Demirdağ, Hatice Gamze; Altunışık, NihalHerpes zoster (HZ) varisella enfeksiyonu sonrası arka kök gangliyonlarına yerleşen varisella zoster virüsünün (VZV) reaktivasyonu sonucu, latent kaldığı gangliyonun innerve ettiği dermatom bölgesinde veziküler lezyonlarla ortaya çıkar. Sıklıkla yaşamın ilerleyen dönemlerinde görülür. Zonada en sık tutulum torasik dermatomda olmaktadır. Kraniyal sinir tutulumu ise en sık olarak trigeminal sinirde olup, oftalmik dalın etkilenmesi (oftalmik zona), maksiller ve mandibuler dal tutulumuna göre yaklaşık yirmi kat daha sıktır. Ramsay-Hunt sendromu, varisella zoster virüsünün reaktivasyonuyla ortaya çıkan bir kraniyal polinöropatidir. Herpes zoster enfeksiyonları içerisindeki sıklığı %1 olarak tanımlanmıştır. Maksiller dal tutulumunun nadir olması ve beraberinde Ramsay-Hunt sendromu bulunması yönüyle enteresan bulunan hastanın sunulması uygun görülmüştür.Öğe Maksiller Dermatomu Tutan Bir Ramsay-Hunt Sendromu Olgusu(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2014) Saraç, Gülbahar; Şenol, Mustafa; Demirdağ, Hatice Gamze; Altunışık, NihalHerpes zoster (HZ) varisella enfeksiyonu sonrası arka kök gangliyonlarına yerleşen varisella zoster virüsünün (VZV) reaktivasyonu sonucu, latent kaldığı gangliyonun innerve ettiği dermatom bölgesinde veziküler lezyonlarla ortaya çıkar. Sıklıkla yaşamın ilerleyen dönemlerinde görülür. Zonada en sık tutulum torasik dermatomda olmaktadır. Kraniyal sinir tutulumu ise en sık olarak trigeminal sinirde olup, oftalmik dalın etkilenmesi (oftalmik zona), maksiller ve mandibuler dal tutulumuna göre yaklaşık yirmi kat daha sıktır. Ramsay-Hunt sendromu, varisella zoster virüsünün reaktivasyonuyla ortaya çıkan bir kraniyal polinöropatidir. Herpes zoster enfeksiyonları içerisindeki sıklığı %1 olarak tanımlanmıştır. Maksiller dal tutulumunun nadir olması ve beraberinde Ramsay-Hunt sendromu bulunması yönüyle enteresan bulunan hastanın sunulması uygun görülmüştür.Öğe Mucocele formation after wisdom teeth removal: A case report(2014) Saraç, Gülbahar; Altunışık, Nihal; Demirdağ, Hatice Gamze; Şener, SerpilAbstract: Mukoseller, ağız içinde sık görülen, farklı boyutlarda olabilen müsin dolu küçük keseciklerdir. Genellikle travma sonrası meydana gelmektedir. Çoğunlukla genç erişkinlerde ve çocuklarda görülür. Mukosellerin büyük bir kısmı minör tükürük bezlerinden kaynaklanır. İyi huylu olmalarına rağmen, kemik erozyonuna yol açarak komşu dokularda basıya neden olabilirler. Yirmi dokuz yaşında bayan hasta, polikliniğimize ağız içinde sağ arka tarafta yaklaşık bir yıldır olan şişlik ve hafif ağrı şikayeti ile başvurdu. İki yıl önce aynı lokalizasyondan yirmi yaş gömülü diş operasyonu geçirdiğini belirtti. Hastanın öyküsü ve lezyonun klinik görünümü nedeniyle mukosel tanısı konuldu. Literatürde şuan ki bilgimize göre yirmi yaş dişi çekimi sonrası bildirilen mukosel olgusu olmaması nedeniyle sunulması uygun görülmüştür. Anahtar Kelime: Mukosel; Yirmi Yaş Dişi Cerrahisi; Oral Kavite.Öğe Primary cutaneous anaplastic large cell lymphoma initially clinically considered to be pyoderma gangrenosum(2017) Şener, Serpil; Altunışık, Nihal; Saraç, GülbaharPrimary CD30+ anaplastic large cell lymphoma, which is generally seen in adults, is the second most common cutaneous T-cell lymphoma after mycosis fungoides. The lesions are characterized by red-brown plaque or nodules often with ulceration. Although usually solitary, there may occasionally be multiple lesions. Here in this case report, a 44-year old male patient with multifocal primary cutaneous anaplastic large cell lymphoma is presented. Primary cutaneous anaplastic large cell lymphoma is a rare disease especially when it is multifocal and has no systemic involvement like in this case. Therefore this case is found valuable to share
