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Öğe Assessment of change in neutrophil-lymphocyte ratio, platelet-lymphocyteratio in patients with acute and chronic urticaria(2018) Sarac, Gulbahar; Mantar, İrem; Sener, Serpil; Cenk, Hülya; Kapicioglu, YeldaAim: Urticaria is a skin disease characterized by erythematous, oedematous, itchy,and spontaneously disappearing urticaria lesions. One of the most common skin diseases, it is the most common reason underlying the presentations to emergency departments. Our objective is to investigate the role of systemic inflammation in urticaria pathogenesis by measuring the indicators of NeutrophilLymphocyte ratio (NLR) and Platelet-Lymphocyte ratio (PLR) in routine hemograms in patients with acute and chronic urticaria. Material and Methods: Of patients visiting the Dermatology Policlinic of İnönü University Medical School Hospital between July 2017 and February 2018, 69 patients diagnosed with acute urticaria and 188 patients diagnosed with chronic urticaria as well as 90 healthy people taken as controls with an age range of 18to 70 were included in our study. Blood values of patients were studied retrospectively. (For the study, a Research Ethics Approval was obtained from Malatya Research Ethics Board.) Results: No significant difference was detected among the study groups in terms of demographic properties. Whereas a significant difference was noted among the three groups with regard to NLR values, no statistically significant difference was detected among the groups with respect to PLR values. No statistically significant difference was observed between the group of patients with urticaria and the control group in terms of erythrocyte distribution(p:0.01). On the other hand, when the patient group with chronic urticaria was divided into two subgroups as patients with a complaint duration of 90 days and less, and those with a complaint duration of more than 90 days and evaluated, no statistically significant difference was detected between these groups in terms of RDW, lymphocytes, neutrophils, platelets, NLR and PLR values Conclusion: In our study, we have determined that systemic inflammation has increased in the group of patients with urticaria as compared to the control group. What’s more interesting in this study is our conclusion that the pathways involved in continued inflammation do not change by time in chronic urticaria.Öğe Association Between Initial Findings Leading to Behcet's Disease Diagnosis and Further Organ Involvements(Wolters Kluwer Medknow Publications, 2022) Yanatma, Irem; Sarac, Gulbahar; Cenk, Hulya; Arslan, Selami; Durmaz, Imge; Ay, GoncaObjectives: Studies show that the symptoms are clustered in certain ways in Behcet's disease (BD), which causes involvement of multiple organs. We aimed to investigate the association between clinical findings at onset and further organ involvements, which may occur during follow-up. Materials and Methods: A total of 363 patients diagnosed with BD in accordance with the International Criteria for BD (ICBD) between 2003 and 2019 at the Inonu University were included in the study, and all the first findings were compared with further organ involvements. Results: A statistical significance was detected between erythema nodosum like lesions and both pulmonary (P = 0.002) and vascular (P = 0.022) involvements. The frequency of neurological involvement was higher in patients with papulopustular/pseudo-follicular lesions (P = 0.043). Gastrointestinal involvement was detected in 33.3% of the patients with herpetiform aphthae. The frequency of ocular involvement was significantly higher in patients with a negative pathergy test result (P = 0.013). Conclusion: The clinical clusters in BD may provide a predictive value about the disease course for clinicians. Although it has been shown that there is an association between some clinical findings and involvements which are mentioned before, this is one of the most comprehensive studies according to us. The clinical clusters in BD may provide a predictive value about the disease course for clinicians. Although it has been shown that there is an association between some clinical findings and involvements in the literature, this is one of the most comprehensive studies as far as we know.Öğe Childhood trauma and emotion regulation in psoriasis(2023) Aygul, Bedriye Ilkay; Zayman, Esra Porgalı; Sarac, GulbaharAim: The present study aimed to determine if there is any relationship between childhood traumas, emotion regulation, depression, and anxiety with psoriasis severity; it also attempted to find out whether these factors affect the development of psoriasis. Materials and Methods: This study enrolled 100 patients with psoriasis aged 18-65 years and 100 healthy volunteers free of any form of psychiatric treatment, active psychiatric symptoms, and dermatological diseases. Sociodemographic Data Form, Childhood Traumas Scale (CTS), Difficulties in Emotion Regulation Scale (DERS), Hamilton Anxiety Scale (HAM-A), and Hamilton Depression Scale (HAM-D) were filled by the study subjects. Results: The patients and controls were compared with respect to HAM-D, HAM-A, CTS, and DERS scales. The patients had higher HAM-D, HAM-A, CTS Physical abuse, CTS Physical neglect CTS Emotional neglect, CTS Sexual abuse, CTS Total, DERS Clarity, DERS Impulse scores than the controls (Table 2) (p<0.001, p:0.011, p:0.021, p:0.005, p<0.001, p:0.045, p<0.001, p<0.001, respectively). Conclusion: Psoriasis should be treated in collaboration of dermatology, psychiatry, immunology, rheumatology, and even medical pharmacology departments.Öğe Comparison of Antiaging Effects on Rat Skin of Cog Thread and Poly-L-Lactic Acid Thread(Lippincott Williams & Wilkins, 2019) Kapicioglu, Yelda; Gul, Mehmet; Sarac, Gulbahar; Yigitcan, Birgul; Gozukara, HarikaBACKGROUND Polydioxanone Cog thread and poly-L-lactic acid (PLLA) thread have been used clinically for lifting and antiaging purposes. However, the histological changes in tissue and the efficacy of these 2 different types of thread have not been compared. OBJECTIVE This study used hematoxylin and eosin (H&E) staining, Masson's trichrome staining, and electron microscopy (EM) to compare the results associated with the use of Cog thread and PLLA thread in rat skin. METHODS Thirty female rats were divided into 3 groups of 10 rats each: a control group; a Cog group; and a PLLA group. Biopsy specimens obtained at 1, 3, and 6 months were examined using H&E, MT, and EM. RESULTS Although significant increases were observed in dermal thickness and the numbers of fibroblasts in the PLLA group compared with the control group within the first month (p: .019), there were no significant differences between the Cog and control groups during this period (p: .245). Dermal thickness (p: .002) and numbers of fibroblasts (p: .001) were similar in samples obtained from the PLLA and Cog groups at 3 and 6 months, and both groups showed significantly improved outcomes compared with the control group. CONCLUSION Poly-L-lactic acid and Cog sutures were effective in facial rejuvenation; both increased dermis thickness and stimulated collagen production.Öğe Comparison of polycaprolactone and calcium hydroxylapatite dermal fillers in a rat model(Wiley, 2021) Yanatma, Irem; Sarac, Gulbahar; Gul, Mehmet; Gul, Semir; Kapicioglu, YeldaPolycaprolactone (PCL) and calcium hydroxylapatite (CaHA) are semipermanent dermal fillers that are frequently preferred in the last decade. This study aims to compare the effects of these two fillers in the rat skin. A total of 30 female rats were divided into; control, PCL, and CaHA group. Tissue samples taken at the second and fourth month were stained with hematoxylin-eosin, Masson trichrome, collagen type 1, and 3 immunohistochemical antibodies. Collagen density was quantitatively compared using the Image J computer program. At 2 and 4 months, the density of collagen increased in both filler groups compared to the control group. There was no significant difference between collagen density or type 1 and type 3 collagen H scores in the filler groups. The number of fibroblast nuclei was significantly higher in the PCL group at 4 months compared to the other two groups. Dermis thickness was found to be superior in both filler groups compared to the control group at the fourth month, there was no significant difference between the filler groups. We compared the effect of CaHA and PCL filler on collagenization histologically and immunohistochemically. We found that PCL and CaHA fillers are effective in increasing dermal collagen density, type 1 and type 3 collagen amount, and preventing dermis atrophy and showed that they have no advantage over each other in this respect. We have shown that PCL filler provides more fibroblast increase compared to CaHA filler and the effect of stimulating fibroblast proliferation takes longer.Öğe Comparison of the efficacies of polycaprolactone filler and lidocaine-added filler on neocollagenesis in a rat model(Wiley, 2022) Sezer, Suat; Sarac, Gulbahar; Gul, Mehmet; Zayman, Emrah; Kapicioglu, YeldaBackground Polycaprolactone (PCL) is a semi-permanent filler stimulating neocollagenesis. Lidocaine is frequently used to reduce the pain and, however, may have negative effects on collagen. It was aimed to compare the histological changes on rat skin and efficacies of PCL filler and lidocaine addition. Objective In this study, results of PCL and PCL+Lidocaine application on rat skin were compared using hematoxylin-eosin (H&E) staining, Masson's trichrome (MT) staining, and electron microscope (EM). Methods A total of 30 adult female rats were divided into three groups: the control group, the PCL group, and the PCL+Lidocaine group. The tissue samples taken at months 2 and 4 were examined using H&E, MT, and EM. Results At month 2, dermis thickness, fibroblast count, and collagen fiber diameter increased similarly in the PCL and PCL+Lidocaine groups. Collagen fiber diameter was significantly higher in the PCL group than in the PCL+Lidocaine (p:0.016) and control groups (p:0.009). At month 4, no significant difference was detected between the PCL and PCL+Lidocaine groups in terms of fibroblast count, collagen fiber count, and collagen fiber diameter; dermis thickness was lower in the PCL+Lidocaine group at month 4 (p < 0.46). Dermis thickness, fibroblast count, collagen fiber count, and collagen fiber diameter were found to be significantly lower than in the PCL and PCL+Lidocaine groups. Conclusions Our study showed that lidocaine addition to PCL filler does not affect the efficacy of the filler and PCL filler stimulates neocollagenesis.Öğe A comparison of the efficacy and tolerability of topical agents used in facial Demodex treatment(Wiley, 2019) Sarac, GulbaharBackground: Demodex spp. is the most common ectoparasite in humans. This parasite is believed to play a role in the etiology of many dermatological and ocular disorders. Aim: The aim of this study was to compare the efficacy and tolerability of the sulfur-sodium sulfacetamide combination, crotamiton, and permethrin, which are three topical agents commonly used in Demodex treatment. Methods: A total of 28 patients with primary demodicosis and 44 patients with Rosacea + Demodex were included in the study. The pretreatment and post-treatment Demodex spp. counts, patient satisfaction, and erythema decrease rates were compared. Results: Analysis of the efficacy of these topical agents on Demodex revealed that all three significantly decreased the number of parasites. The patient satisfaction was higher in the sodium acetamide group than the 10% crotamiton and 5% permethrin groups, and clinical evaluation (erythema/ papulopustules and white plugs) was better in the sodium acetamide group than the other groups but no statistically significant difference was found in terms of patient satisfaction and clinical evaluation. Conclusion: The sulfur-sodium combination, crotamiton, and permethrin are the three agents commonly used in the treatment of Demodex spp. and all significantly decreased the Demodex count. The three agents were similar in terms of tolerability. Our study needs to be supported with others on larger patient series.Öğe Dermatological signs in liver transplant recipients(Wiley, 2021) Sarac, Gulbahar; Ozcan, Kubra Nur; Baskiran, Adil; Cenk, Hulya; Sarac, Mehmet; Sener, Serpil; Yilmaz, SezaiBackground In recent years, the number of liver transplantations for advanced-stage liver diseases has considerably increased and the patients have a wide range of dermatologic manifestations. Aim This study aims to reveal cutaneous, mucosal, and nail lesions in liver transplant recipients in quite large patient series. Patients/Methods The study included 520 patients in the Inonu University Liver Transplantation Institute. New and followed-up patients attended to the study between May and October 2019. The patients were examined by a dermatologist, and their data were recorded. Results The study included 163 female and 357 male patients with the main age of 44.20 +/- 18.18 (range: 1-83 years), and 465 livers (89.4%) were taken from live donors, while 54 livers (10.4%) were taken from cadavers. A total of 314 (60.4%) patients had dermatophyte infections, 174 (33.4%) patients had pathological nail changes, and 427 (82.1%) patients had oral mucosal lesions. Graft-versus-host disease (GVHD) developed in 9 (1.73%) patients after the transplantation, and 5 patients died of GVHD. Four patients had cutaneous malignancies. Conclusions Tumoral and nontumoral dermatological diseases may be encountered following the transplantation depending on underlying liver disease, immunosuppressive treatment, the graft itself, or any primary cutaneous disease. Liver transplantation recipients require a multidisciplinary clinical approach, and dermatological care must be an integral part of this approach.Öğe Determination of sunscreen and cosmetic product use awareness in adolescents(2019) Sarac, Gulbahar; Kayhan Tetik, Burcu; Sener, Serpil; Mantar, İrem; Kapicioglu, YeldaAim: Using an appropriate sunscreen is very important because the role of sun rays in development of skin cancer is well known. Besides, the recent increase in the use of cosmetics among adolescents is noteworthy. In this study, we aimed to determine the frequency of using cosmetics and the level of awareness of harmful effects of the sun, in adolescents. Material and Methods: In this cross-sectional descriptive study, a questionnaire consisted of 25 questions was applied, on voluntary basis, in middle schools. Results: A total of 607 students participated in the study; 434 participants were female students (71.5%), 173 were male students (28.5%) and the average age was 17 years. The question “Do you think it is necessary to protect from the sun?” is answered as “yes” by 361 of the female students (81.1%) and 109 of the male students (62.3%). The question “Do you use sunscreen?” is answered as “Yes” by 33.3% of all participants. Conclusion: In our study, we found that adolescents had a good understanding of the harmful effects of sun, but in contrast to this, we found that the use of sunscreen products was at very low levels. We think that education and methods for building awareness in this regard will be effective.Öğe Effect of hemostatic agent Ankaferd on growth factors and hydroxyproline which play a role in wound healing(Bilimsel Tip Yayinevi, 2015) Sezgin, Sevgi; Sarac, Gulbahar; Turkoz, Yusuf; Senol, MustafaObjective: There have been a lot of topical and systemic agents to provide an ideal scar formation and decrease the periods of wound healing process by affecting the factors of healing (inflammatory cells, thrombocytes, extracellular matrix etc.). Ankaferd is an extract used as a hemostatic agent which is prepared in certain ratios of five herbal contents which are used in traditional Turkish medicine. In our study, we observed the effects of Ankaferd on wound healing. Materials and Methods: So that, the wounds were created with 8 mm punch biopsy on the back of 36 rats which were seperated into 4 groups of 9 rats. No treatment was done in Group D which is the control group while Group A took topical Ankaferd treatment twice a day, Group B treated with silver sulfadiazine twice a day, and Group C put on base cream twice a day which did not include any active agent. The rats were followed for 15 days macroscopically on 0, 3, 7 ve 15th days by taking biopsies and the levels of hydroxyproline, epidermal growth factor (EGF), vascular endothelial growth factor (VEGF) and platelet derived growth factor (PDGF) were analysed from the tissue. Results: Th ere were no significiant differences by means of EGF and PDGF levels between the all groups. The only significiantly lower growth factor was VEGF in the silver sulfadiazine group. The wound healing process was determined faster in silver sulfadiazine and Ankaferd groups. There was no significiant difference in hydroxyproline levels between these groups and the hydroxyproline levels were significiantly higher in control group. At the end of our study, it was detected that Ankaferd accelerated the healing process similar to silver sulfadiazin, in comparison to control and base cream groups according to the macroscopic results.Öğe Effectiveness and safety of 2940-nmmultifractional Er:YAGlaser on acne scars(Wiley, 2020) Cenk, Hulya; Sarac, GulbaharErbium: Yttrium-aluminum-garnet laser (Er: YAG) treatment has been used in resurfacing the acne scars for a long time; however, we could not find any study reporting the recovery rates after each session of the treatment. In this study, we aimed to report the improvement rates after each session. We retrospectively analyzed the data of 35 patients with acne scars treated with fractional ablative Er: YAG laser. The patients received one to four sessions of treatment with 4-week intervals and improvement rates were recorded after each session. Data are available on request from the authors. The improvement rate of the lesions varied between 1% and 25% in 34 patients at the end of the first session, while in one patient, the improvement rate was detected as 26% to 50%. At the end of the fourth session, the rate of improvement was 26% to 50% in 14 out of 24 patients and 51% to 75% in 10 patients. None of the patients showed a 76% to 100% improvement at the end of the fourth session, whereas 48.6% of the patients were satisfied with the treatment. In patients with a high expectation of an excellent improvement, a higher number of sessions of the laser treatment and/or combination treatments with different treatment methods should be planned.Öğe Effectiveness of topical Nigella sativa for vitiligo treatment(Wiley, 2019) Sarac, Gulbahar; Kapicioglu, Yelda; Sener, Serpil; Mantar, Irem; Yologlu, Saim; Dundar, Cihat; Turkoglu, MuratVitiligo is a pigment disease characterized by the disruption of melanocyte structure and function. Its etiology is unknown; however, genetic predisposition, biochemical factors, and neural mechanisms are thought to be effective. Although many agents are being used for its treatment, generally there is no absolute cure. The aim of the present study is to evaluate the effectiveness of topical Nigella sativa seed oil on vitiligo patients. Thirty-three vitiligo patients were included in the study. Totally 47 areas were evaluated in all patients. Cream containing N sativa seed oil was topically applied to hands, face, and genital region two times a day for 6 months. Statistically significant repigmentation was detected in hands, face, and genital region, the three treatment areas, and the p values are found .005, .001, and .004, respectively. N sativa can be used as an adjuvant therapy that can contribute to the treatment especially in sensitive skin areas like genital region.Öğe Efficacy of 2940 nm Multifractional Er: YAG Lasers in Self-inflicted Razor Blade Incision Scars(Wiley, 2022) Cenk, Hulya; Sarac, GulbaharBackground Deliberate self-harm (DSH) can be defined as self-inflicted injury without an intention to suicide, and it may result in scar formation with a particular shape. Aims There is no treatment algorithm for DSH scars, nor is there a gold standard for the treatment of hypertrophic scars. Therefore, we aimed to share our experience with Er: YAG laser treatment of self-inflicted razor blade incision scars. Patients/Methods The study involved 18 patients with DSH scars treated with fractional ablative Er: YAG laser (MCL 31 Asclepion laser Technologies) between 2017 and 2020, with the parameters of 40 J/cm(2), 300 mu s, and 4 Hz. The sessions were repeated by increasing 10 joules in every session with 4-week intervals until reaching a maximum of 80 joules. The patients were evaluated retrospectively by two different dermatologists in terms of scar improvement over digital photographs taken before and 4 weeks after the treatment. Evaluations have been made based on a 4-point score (0:no change, 1:1%-25% mild, 2:26%-50% moderate, 3:51%-75% well, and 4:76%-100% excellent improvement). Results After the third session, 90.9% of the patients showed a moderate improvement. After the fourth session, only 27.2% of the patients had a good, and 63.2% of the patients had a moderate improvement rate. Conclusions Er: YAG laser is a safe and effective treatment method for the hypertrophic scars induced by razor blades. Also, we believe that combined treatments with other treatment modalities will provide better results in DSH scars.Öğe Efficacy of 577-nm Pro-Yellow laser in port wine stain treatment(Wiley-Hindawi, 2019) Sarac, Gulbahar; Kapicioglu, YeldaA port-wine stain (PWS) is a congenital capillary malformation that is seen in 0.3-0.5% of newborns. Although many types of lasers have been used to treat PWSs, few studies have investigated the efficacy of 577-nm Pro-Yellow lasers. The aim of this study was to establish the efficacy of Pro-Yellow lasers in PWS treatment. In total, 26 patients, comprising 15 females (57.7%) and 11 males (42.3%) with a mean age of 24.7 +/- 11.8 (range 1-50) years were included in the study. All were treated with a 577-nm Pro-Yellow laser at 4-week intervals, 3-10 times. The sessions initially used scan mode and a fluence dose of 24 J/cm(2) per session, on average. The mean dose was increased by 4 J/cm each session and the maximum dose administered was 44 J/cm(2). A mean regression of 68.8 +/- 13.9% in the size of the lesions over 5.23 +/- 2.7 sessions was observed. There was no statistically significant difference between the female and male patients when they were compared in terms of the number of treatment sessions (p = .789) and treatment success (p = .39). These case series demonstrate that the Pro-Yellow laser is a safe and well-tolerated treatment for PWSs. However, deep-seated lesions required more treatment sessions and it was observed that clinically the lesions did not completely disappear.Öğe Evaluation of changes in neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in patients with vitiligo(2019) Sarac, Gulbahar; Altunisik, Nihal; Sener, Serpil; Hakverdi, GuldenAim: Vitiligo is an acquired disease with loss of melanocytes, etiology of which is unclear. The aim of this study is to determine the role of systemic inflammation in vitiligo by measuring the Neutrophil-Lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR) markers included in routine hemogram test, in patients with vitiligo.Material and Methods: The study was carried out by reviewing the data of patients who applied to İnönü University Faculty of Medicine Dermatology Polyclinic and diagnosed with vitiligo after Wood’s lamp examination, between July 2012 and February 2018. The study was performed retrospectively by reviewing patient files and ethics committee approval was not obtained.Results: A total of 170 individuals including 79 vitiligo patients and 91 healthy individuals were included in the study. When the vitiligo patients and healthy control group were compared in terms of routine hemogram parameters, statistically significant differences were found in terms of erythrocyte distribution width (RDW), but there were no statistically significant differences in terms of NLR, PLR, lymphocyte, neutrophil, platelets and White bloodcell (WBC) counts.Conclusion: In our study, only RDW value was found to be higher in patients with vitiligo compared to healthy controls, and no difference was found in other parameters indicating systemic inflammation.Öğe Evaluation of Patients with Cutaneous Leishmaniasis Who Admitted to Dermatology Clinic in Kahramanmaras Sutcu Imam University Medical Faculty(Duzce Univ, 2017) Sener, Serpil; Karaman, Ulku; Hakverdi, Gulden; Sarac, Gulbahar; Tetik, Burcu KayhanObjective: Leishmaniasis is a group of diseases, in different clinical forms, caused by the intracellular protozoan parasites, Leishmania species. The disease is transmitted by a female sand fly infected with the parasite sucking blood from people. Leishmania species causes three main clinical forms: cutaneous, mucocutaneous, and visceral disease. The clinical forms may vary by species and/or region of acquisition. Two forms are observed in Turkey; visceral leishmaniasis and cutaneous leishmaniasis. The aim of this study is to examine the status of Cutaneous Leismaniasis(CL) in the Kahramanmaras province and contribute to the prevention of the disease in this region. Methods: 20 CL cases were reported officially in 2009. CL was diagnosed by skin biopsy or smear. Intralesional meglumine antimoniate was applied for patients treatment. Results: Out of 20 cases, 12 and 8 were female and male. According to smear and biopsy, was found positive in 13 cases, and negative in 7 cases and the results of biyopsy was assessment as CL. Conclusion: By defining the status of CL in the region, the study can be considered to contribute to the planning of methods of intervention, public health education and personal preventative precautions.Öğe An evaluation of the efficacy of a single-session 577 nm pro-yellow laser treatment in patients with postacne erythema and scarring(Wiley, 2021) Sarac, Gulbahar; Kapicioglu, Yelda; Cenk, HulyaErythema and scarring are among the most common complications of severe inflammatory acne. In this study, we aimed to share our experience with pro-yellow laser and document the efficacy and safety of this treatment in postacne erythema and scarring. The study included 40 patients, 24 (60%) females, and 16 (40%) males with a mean age of 29.5 +/- 8.16 (min. 18 years, max. 57 years). The pro-yellow laser was applied to all patients as a single session with irradiation of 22 J/cm(2). Improvement in postacne erythema and scars were evaluated after the treatment. The study included 40 patients, 24 patients (60%) were females and 16 patients (40%) were males with the mean age of 29.5 +/- 8.16 (ranged between 18 and 57 years old). A total of 21 patients (52.5%) had good improvement (51%-75% regression), 10 patients (25%) had excellent improvement (76%-100% regression), and a moderate improvement (26%-50%) was detected in 9 patients (22.5%). Also, there were mild improvement (1%-25%) in 20 patients (76.9%) and a moderate improvement (26%-50%) in 6 patients (23.1%). We found that pro-yellow laser is highly effective in the treatment of postacne erythema, while its effectiveness was mild to moderate in atrophic acne scars. Also, it has been observed that the pro-yellow laser system can be used safely immediately after cessation of systemic isotretinoin treatment.Öğe Evaluatıon of sunbathıng and protectıon awareness accordıng to thesocıodemographıc characterıstıcs of ındıvıduals aged above 65 years(Gunes kıtabevı ltd stı, m rauf ınan sok no 3, ankara, sıhhıye 06410, turkey, 2018) Kayhan Tetik, Burcu; Sarac, Gulbahar; Mete, Burak; Sener, Serpil; Kalem, Hulya; Kilic, EvrimIntroduction: Because excessive exposure to solar radiation contributes to the aging of skin and the risk of skin cancer, protection from sunlight has become an important public health problem. This study aims to assess the knowledge level of individuals aged > 65 years regarding sun exposure and their current use of sunscreen products. Materials and Method: A questionnaire consisting of 22 questions was prepared to measure sun protection awareness and use of sunscreen products by individuals aged > 65 years. Between July and August 2017, the questionnaire was administered to 603 patients who presented to outpatient clinics. The data were analyzed using SPSS 22 software; a p-value of. < 0.05 was considered significant. Results: The average age of the 603 participants was 67.8 years; 202 (33.5%) of them stated that they generally remained in the sun for 4-6 h, and 518 (86.3%) indicated that they had not received any information about sun protection. Conclusion: We found that individuals aged >= 65 years had insufficient knowledge of the dangers of excessive sun exposure and were not protected from it. In order to reduce the risk of skin cancer in Turkey, education regarding lifestyle modification, sun protection, and use of sunscreen should be provided and relevant health policies should be formulated for these trainings to become a part of lifestyle there.Öğe Increased frequency of Demodex blepharitis in rosacea and facial demodicosis patients(Wiley, 2020) Sarac, Gulbahar; Cankaya, Cem; Ozcan, Kubra Nur; Cenk, Hulya; Kapicioglu, Yelda KarincaogluBackground Rosacea is an inflammatory disease with 50% of ocular involvement rate. Primary demodicosis is an eruption caused by Demodex mites, and there is no data about the rate of ocular involvement in primary demodicosis. Aims In this cross-sectional study, it is aimed to reveal the frequency of Demodex blepharitis in rosacea and primary demodicosis patients. Methods In total, 58 rosacea, 33 primary demodicosis patients, and 31 healthy volunteers were included in the study. Four samples were obtained from eyelashes with a forceps and from facial skin by standardized skin surface biopsy. A positive result is described as detecting at least one Demodex mite on an eyelash or at five mites in the face. The patients were also examined by an ophthalmologist in terms of ocular involvement. Results Both rosacea and primary demodicosis patients had significantly more complaints like burning and stinging in the eyes compared to the control patients (P = .001). Primary demodicosis and papulopustular rosacea patients had the highest numbers of eyelash mites, respectively, and significantly a higher rate of blepharitis than the control group. Conclusion As a result, the Demodex count was significantly higher in the primary demodicosis and rosacea patients than the control group. We think that every Demodex-positive patients should be evaluated for also eyelash mites to prevent a possible chronic blepharitis.Öğe Inguinal Papule with a Milky Secretion(Karger, 2021) Cenk, Hulya; Uner, Meral; Sarac, Gulbahar[Abstract Not Available]
