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Öğe Aim: Background: The aim of this study is to compare the microvessel densities of different normal gastric regions and to determine the effects of sleeve gastrectomy on the microvessel density of tissues alongside the remnant stomach. Material and Methods: Twenty male Wistar albino rats were divided into two groups. Rats in the control group were immediately sleeve gastrectomized under anesthesia and a wedge resection of the esophagogastric junction (EGJ), the fundus, corpus and antral gastric regions was performed, before sacrifice. Meanwhile, rats in the experiment group also underwent sleeve gastrectomy but were not sacrificed until the 5th postoperative day. At this point, gastric tissues alongside the sleeve gastrectomy area were then wedge-resected. The microvessel densities of these two groups were evaluated and compared. Results: When comparing distinctive gastric regions within the control group, the microvessel density of the esophagogastric junction was found to be less than in the corpus or fundus (20.04±4.45; 36.28±9.98, 39.4±9.57; p <0.01). When comparing the control and experiment groups, No significant difference in the microvessel density of the esophagogastric junction was found (20.04 ± 4.45, 24.63 ± 8.91, p> 0.05). The sleeve gastrectomy also had no significant effect on the microvessel densities at the esophagogastric junction or corpus (24.63±8.91, 22.24±7,63; p> 0.05). Conclusion: The esophagogastric junction has a lower microvessel density than the corpus in a normal stomach. Sleeve gastrectomy has no adverse effect on the microvessel density of the esophagogastric junction(2018) Sargin, Mehmet; Uluer, Mehmet SelcukAim: Lumbar spine surgeries can be performed under general anesthesia or spinal anesthesia. We aimed to compare the effects of spinal and general anesthesia on intraoperative bleeding in patients undergoing lumbar disc surgery. Material and Methods: Fifty patients scheduled to undergo elective single-level lumbar discectomy under spinal or general anesthesia were studied. The amount of blood loss was calculated by subtracting the wash solutions from the amount in the aspirator reservoir and evaluating bleeding in the gauze used throughout the operation. The time between the first incision and the final suture was evaluated as the surgical time.Patients’demographic data, duration of surgery, amount of fluid given intraoperatively, intraoperative hemodynamic data, intraoperative blood loss, intraoperative/postoperative ephedrine requirements , postoperative nausea and vomiting and the duration of stay in PACU were evaluated. Results: In group S, intraoperative blood loss was 203.00±108.73 ml, while in group G it was 198.00±106.40. There were no statistically difference between the groups (p=0.884). Inthe duration of surgery, amount of fluid given intraoperatively, intraoperative ephedrine requirements was compared, there wereno difference between the groups too (p=0.085, p=0.056 and 0.448, respectively). Conclusion: In this study, it was shown that general and spinal anesthesia did not affect major parameters such as intraoperative bleeding in patients undergoing.Öğe Anesthetic and analgesic approach in total knee arthroplasty: A national survey study(2021) Aslanlar, Emine; Sargin, MehmetAim: Although the optimum anesthetics and analgesic choice for total knee arthroplasty is a heavily debated topic in recent years, the failure to reach any ideal consensus on this topic leads clinicians to adopt different approaches. This study was conducted to assess differences in general anesthetic and analgesic approaches toward the total knee arthroplasty across Turkey. Materials and Methods: Our 28-item survey was presented online to physicians who work as Anesthesiology and Reanimation specialists in Turkey and agreed to participate in the study. The survey includes questions about the techniques preferred by the clinicians in the management of anesthesia and postoperative analgesia in TKA and the main reasons underlying their preferences. Results: 255 anesthesiologists, i.e. 72 (28.1%) faculty members and 183 (71.9%) specialists, completed the study in full. According to our survey, spinal anesthesia (61.3%) comes first in the selection of an anesthetic method in TKA, followed by the Combined Spinal-Epidural Anesthesia (32.4%). The spinal anesthesia is the most frequently preferred method in training and state hospitals and Combined Spinal-Epidural Anesthesia is the most frequently preferred method in private hospitals. The use of peripheral nerve blocks is 49.8% (127). Femoral nerve block is preferred with 79.7%, followed by adductor canal block with 36.1%. The rate of use of intravenous patient-controlled analgesia is 38.1% and the most commonly preferred analgesia is Tramadol (69.1%). 63.1% of those using epidural anesthesia do not use any epidural patient-controlled analgesia device. The physicians reported that the lack of a team to follow up epidural patient-controlled analgesia device (50.9%) as the most common reason for not choosing epidural patient-controlled analgesia. Conclusion: Regional anesthesia is the first preference in the anesthesia management of total knee arthroplasty in our country. In postoperative analgesia practice, peripheral nerve blocks are preferred at a higher rate than epidural and intravenous patient controlled analgesia.Öğe A Cross-Sectional Study of the Prevalence of Cardiovascular Disease in Adults with Type 2 Diabetes in Turkiye: The CAPTURE Study(Aves, 2022) Bayram, Fahri; Bayraktaroglu, Taner; Sargin, Mehmet; Sahin, Ibrahim; Guldiken, Sibel; Dalbeler, Aysegul; Sonmez, AlperObjective: The primary objective of the CAPTURE study was to estimate the prevalence of cardiovascular disease (CVD) in adults with Type 2 diabetes mellitus (T2DM) across 13 countries from 5 continents. Here, we present the findings from Turkiye. Material and Methods: The non-interventional, cross-sectional CAPTURE study (NCT03811288; NCT03786406) was conducted across 15 centers in Turkiye. Standardized demographic and clinical data were collected from adults with T2DM who were treated by primary or specialist care physicians. The prevalences of CVD and its 7 subtypes were estimated. Descriptive statistics were used for data analysis. Results: Amongst the 801 participants (n=200 from primary care, n=601 from specialist care) with T2DM enrolled, 250 had established CVD, an estimated weighted prevalence of 31.2% (28.0-34.4) 95% confidence interval. Atherosclerotic CVD contributed to the majority (85.6%) of the CVD cases. An estimated 24.0% of the Turkiye sample had coronary heart disease (CHD). Heart failure was the second most predominant CVD subtype in Turkiye is correct sample (5.4%), followed by cardiac arrhythmia and conduction abnormalities (4.7%). Sodium-glucose co-transporter 2 inhibitors and glucagon-like peptide-1 receptor agonists with cardiovascular (CV) benefits were prescribed to 17.5% and 0.1% of the patients, respectively. Conclusion: Approximately 30% of participants with T2DM had established CVD in the CAPTURE Turkiye population, comparable to the global pooled prevalence. CHD was the major contributor and encompassed approximately 75% of the CVD cases. The use of glucose-lowering medication with CV benefits was low compared to the global pooled population, which may be due to the lack of reimbursement of these medications in Turkiye.Öğe The effects of spinal neddle on skin puncture pain during spinal anesthesia for caesarian sections: Comparison of 26G Quincke and 26G atraumatic spinal needles(2018) Sargin, Mehmet; Toprak, Hatice; Cebeci, ZubeyirAim: Skin puncture pain during spinal anesthesia is the reason of wincing from spinal anesthesia in many patients. In this study we aimed to compare the effect of two different spinal needles on skin puncture pain during spinal anesthesia for caesarian sections. Material and Methods: Eighty pregnant women scheduled to undergo elective caesarean section under spinal anesthesia were studied. Spinal anesthesia was induced with hyperbaric bupivacaine 10-15 mg via a 26G Quincke (Group Q, n=40) or 26G atraumatic (Group A, n=40) spinal needle in the sitting position at the L3–4 or L4-5 vertebral level using median approach. Skin puncture pain during spinal anesthesia was assessed on a scale of 0 to 10, where 0 means refers no pain and 10 the worst possible pain (0 no, 1–3 mild, 4–6 moderate, 7–10 severe). Results: Skin puncture pain VAS values, median (range) [IQR], were 2(1-5)[1-3] in Group Q and 2(1-7)[1-3] in Group A. There were no statistically differences between the groups (p=0.707). Conclusion: We believe that Quincke and Atraumatic spinal needles don’t have any difference in terms of skin puncture pain during spinal anesthesia for cesarean sectionÖğe The relationship between preoperative and postoperative neutrophil-lymphocyte and platelet-lymphocyte ratio with post-dural-puncture headache in patients undergoing cesarean section(2019) Sargin, Mehmet; Uluer, Mehmet Selcuk; Tutar, Mahmut SamiAim: This study aims to evaluate whether there is a possible relationship between the preoperative and early postoperative period neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio and post-dural-puncture headache in patients undergoing cesarean section.Material and Methods: Two hundred twenty pregnant women scheduled to undergo elective cesarean section under spinal anesthesia, were studied. Patiens demografic data and blood count parameters were noted. Blood was sampled from a peripheral vein for neutrophil/lymphocyte ratio ve platelet/lymphocyte ratio. The time points for sampling blood were as follows: Preoperative; 1 day before and postoperative; within 6-12 hours after cesarean section. The patients were questioned for possible occurrence of spinal anesthesia induced headache on the first and seventh postoperative days. Post-dural puncture headache was evaluated according to the International Classification of Headache Disorders (ICHD-II) diagnostic criteria.Results: A total of 220 patients were enrolled in the study and 217 patients completed the investigation. Post-dural puncture headache was detected in 78 patients and the incidence was 35.9%. The measurements of laboratory parameters were statistically similar between two groups (P > 0.05).Conclusion: Our study results showed no relationship between the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, and post-dural-puncture headache in the preoperative and also, early postoperative period in patients who undergoing cesarean section.Keywords: Post-Dural-Puncture Headache; Neutrophil-Lymphocyte Ratio; Platelet-Lymphocyte Ratio; Cesarean Section.
