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Yazar "Sarihan, M. Ediz" seçeneğine göre listele

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    Apricot tree falls: a study from Malatya, Turkey
    (Allied Acad, 2016) Oguzturk, Hakan; Turgut, Kasim; Turtay, Muhammet Gokhan; Sarihan, M. Ediz; Gur, Ali; Beydilli, Inan; Gurbuz, Sukru
    Introduction: Falls from trees constitute an important and fatal form of injury. The present study aimed to assess the demographic and clinical features of apricot tree falls. Materials and methods: The patients who were admitted to the emergency department with a fall from an apricot tree between June 2015 and September 2015 were recorded prospectively. The age, gender, fall height, fall time, emergency department admission time, vital signs, injury types, treatments and outcomes, Glasgow coma score, and injury severity score, were studied for each patient. Results: There were 30 falls from apricot trees and all of them were male. The mean age was 29 +/- 18.9 years, and 33% of the patients were in the pediatric age group. The patients suffered from extremity (46.7%), spinal system (30%), chest (13.3%), abdomino-pelvic (6.7%), and head (3.3%) injuries. Arm and forearm fractures were ranked first among all the fractures. The majority of the patients (70%) were managed and discharged from emergency department. None of the patients died, and all of them recovered fully. Conclusion: Falls from apricot trees usually lead to only minor injuries. The emergency department has the most important role in the management of these injuries. A considerable amount of patients are children, therefore, clear and feasible rules regarding child workers will reduce falls from apricot trees.
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    Bilateral Ureteral Stones Causing Anuria: A Case Report
    (Aves, 2015) Gur, Ali; Turtay, Muhammet Gokhan; Gurbuz, Sukru; Oguztruk, Hakan; Sarihan, M. Ediz; Oguz, Fatih; Derya, Serdar
    Introduction: Bilateral ureteral stone is not known to frequently result in anuria during emergency. Case Report: An 18-year-old male patient was admitted to an emergency department with the complaint of sudden inability to urinate. He did not mention any additional complaints. On conducting a physical examination, we could not detect any pathological findings. From the patient's blood tests, potassium and creatinine levels were found to be 6.4 mmol/L and 9.81 mg/dL, respectively. Subsequently, we found bilateral ureteral stones on ultrasonography and non-contrast spiral computed tomography. Urology consultation was requested. The patient undergoing emergency surgery had ureterorenoscopy, bilateral endoscopic retrograde basket, and DJ stents procedures done by urology. During the follow-up, the patient was able to urinate, and his creatinine and potassium levels decreased. The patient was discharged. Conclusion: For patients admitted with complaint of anuria, we should keep in mind that the patient could have bilateral ureteral stones; therefore, he or she may have acute kidney failure and may subsequently require emergency surgery.
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    Dose-Dependent Protective Effect of Ivabradine against Ischemia-Reperfusion-Induced Renal Injury in Rats
    (Karger, 2012) Beytur, Ali; Binbay, Murat; Sarihan, M. Ediz; Parlakpinar, Hakan; Polat, Alaadin; Gunaydin, M. Orhun; Acet, Ahmet
    Background/Aims: This study was designed to investigate the dose-dependent protective effect of ivabradine, a specific inhibitor of the cardiac sinoatrial node, on renal ischemia-reperfusion (I/R) injury in rats. Methods: Rats were divided into six groups: group 1, control; group 2, I/R (60 min ischemia followed by 24 h reperfusion); groups 3 and 4, 0.6-6 mg/kg ivabradine; and groups 5 and 6, sham+0.6-6 mg/kg ivabradine. At the end of the study, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase contents were assayed in the kidney tissues; serum blood levels of urea nitrogen (BUN), creatinine (Cr) and albumin also were determined. Results: Tissue MDA levels were found to be significantly higher in the I/R group, whereas SOD and CAT levels were lower when compared to the control group. Ivabradine (0.6 mg/kg) treatment reduced the MDA levels and elevated the SOD and CAT enzyme activity. Treatment with a dose of 6 mg/kg ivabradine further increased MDA levels and did not ameliorate SOD or CAT activities. Serum levels of BUN and Cr were significantly higher in the I/R group. I/R+0.6 mg ivabradine reduced the elevated BUN and Cr levels. Conclusion:This study indicates that ivabradine exerts a dose-dependent response beyond heart rate reduction against renal I/R injury. Copyright (C) 2011 S. Karger AG, Basel
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    THE EFFECTS OF VINPOCETINE ON THE PREVENTION AND TREATMENT OF THE ISCHEMIA/REPERFUSION INJURY: AN EXPERIMENTAL STUDY
    (Carbone Editore, 2017) Sahin, Levent; Sarihan, M. Ediz; Parlakpinar, Hakan; Polat, Alaadin; Vardi, Nigar
    Object: Histopathological and biochemical effects of vinpocetine, which is an anti-inflammatory and antioxidant agent, on ischemia / reperfusion (I/R) injury were studied in an animal model. Material and methods: Forty Sprague Dawley rats were divided into five groups. Group1 underwent only a right nephrectomy. Group 2 was administrated vinpocetine after right nephrectomy. Group 3 initially underwent a right nephrectomy. Them, left kidney of this group was applied ischemia for 60 minutes, which was followed by reperfusion for 24 hours. Group 4 underwent same steps as group 3; but was administrated vinpocetine 10 mg/kg i.p. before I/R to the left kidney. Similarly, group 5 underwent same steps as group 3 but was administrated vinpocetine 10 mg/kg i.p. after I/R to the left kidney. Results: Plasma BUN and creatinine showed no significant differences between control ( Sham) group and groups that were administrated vinpocetine. Decrease in plasma urea and creatinine was detected group 5, but this finding was not present in group 4. Superoxide dismutase and glutathione reductase levels in groups 4 and 5 were significantly higher than the group 3. Parallel to this, oxidative stress index was higher in the group 3compared to groups 2, 4, and 5 (p<0.05). No significant difference was found between levels of malondialdehite in sham and vinpocetine administrated only group (p<0.005). All groups showed no differences in catalase levels and Total Antioxidant Capacity. Decreased tubular injury was present in the groups administrated vinpocetine before and after I/R. In control and vinpocetine given groups, there were some apoptosis in tubules after tested with caspase 3. Caspase 3 positivity was significantly higher in I/R group compared to control group. Vinpocetine if given after I/R was more effective to prevent apoptosis then to be administrated before I/R. Conclusion: This experimental study showed that vinpocetine promotes achieving better renal functions. The results of this study suggest that vinpocetine may be used in the treatment of renal I/R
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    An Unusual Manner Is Up to Allopurinol: DRESS Syndrome
    (Aves, 2014) Karaman, Esra; Turtay, Muhammet Gokhan; Gurbuz, Sukru; Oguzturk, Hakan; Sarihan, M. Ediz; Bican, Serkan
    Introduction: Allergic reactions can be observed in many different ways in the emergency department. Case Report: Due to itchy skin eruptions, especially on her face and body, a 60-year-old female patient was admitted to the emergency department. It was learned from the history of the patient that the administration of allopurinol was started owing to high uric acid levels in routine examinations 15 days ago. Vital signs were stable in the physical examination. There were erosion and hemorrhagic crusts on the lips and maculopapular lesions that got pale after pressing with common erythema on the oral mucosa, face, body, and back. A dermatology consultation was asked for the patient, with a preliminary diagnosis of Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome. Then, previous treatment of the hospitalized patient was stopped, and antihistaminic and systemic steroid treatments were applied. Consequently, the patient was discharged with full recovery. Conclusion: DRESS syndrome should be considered in patients who are admitted to the emergency department with a history of using allopurinol and have skin lesions and deterioration in liver function tests showing involvement of internal organs.

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