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    An autopsy case of disseminated angioinvasive aspergillosis
    (Egyptian Forensic Medicine Authority, 2012) Samdanci E.T.; Ak S.; Bozdag Z.; Sayin S.
    Angioinvasive aspergillosis is a rare but potentially devastating disease especially in immunocompromised hosts. However diabetes mellitus is one of the chronic conditions that leads to immunosufficiency in patients, it is rarely reported in such cases. Here we aimed to present an autopsy case of disseminated angioinvasive aspergillosis with diabetes mellitus and discuss the other possible underlying reasons for this situation. A 52. year old man with diabetes mellitus operated for the fracture of his L1 vertebra and tibia due to falling down from the third floor of a building. After his death on postoperative 34th day, histopathologic examination of the tissue samples presented multiple hyphae having dichotomous branching at 45-degree angles in infiltration areas. In conclusion, in long-term hospitalized patients with diabetes mellitus, fungal infections should be taken into account and an empirical antifungal therapy is recommended. Besides, sterilization procedures should be obeyed in order to prevent infectious diseases. © 2012 Forensic Medicine Authority.
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    The incidence of non-proliferative and precancerous lesions of reduction mammoplasty: Evaluation of 273 cases
    (2011) Samdanci E.T.; Firat C.; Cakir E.; Ak M.; Sayin S.; Nurkabul Z.
    Background: Reduction mammoplasty (RM) is one of the most commonly performed plastic surgery procedures to treat symptomatic macromasty or to correct asymmetry. Occult breast carcinomas were rarely defined in RM specimens. There are few studies aiming to define the incidence of non-proliferative and precancerous lesions. Material and Methods: We evaluated the pathological findings of the RM specimens that have been submitted to our Center for the last 6 years (2005-2011). Results: A total of 273 cases with bilateral RM were enrolled to the study. Of them, 229 cases had pathological changes. Eight cases (2.9%) had atypical ductal/lobular hyperplasia. One case (0.3%) had lobular carcinoma in situ; however, no invasive breast carcinoma was detected. Other pathological findings included fibrocystic changes, fibrosis, adenosis, fibroadenoma (without complex features), mastitis and duct ectasia. Conclusions: Pathological examination of the RM specimens is quite important to define the lesions precancerous of breast carcinoma. Unknown occult breast lesions could be identified and early interventions may be taken into account.