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    Effects of propolis on biochemical and microbiological parameters in carp (Cyprinus carpio) fillets exposed to arsenic
    (Iranian Fisheries Science Research Inst-Ifsri, 2015) Selamoglu, Z.; Duran, A.; Gulhan, M. F.; Erdemli, M. E.
    The purpose of this study was to investigate the therapeutic effects of propolis on biochemical and microbiological parameters in muscle tissues of carp (Cyprinus carpio, Linnaeus 1758) exposed to arsenic. A sublethal concentration of arsenic (0.01 ppm) and/or 0.01 ppm propolis were administered to fish for seven days. Biochemical parameters [pH, lactic acid, total volatile basic nitrogen (TVB-N), and malondialdehyde (MDA) values] and microbiological changes (mesophilic and psychrophilic bacteria count) were determined in fillet of carp in control, arsenic only, propolis only and arsenic+propolis treatment groups. Results showed that the levels of MDA, lactic acid and TVB-N increased (p<0.05) while there were decreases total counts of psychrophilic, mesophilic bacteria and level of pH in arsenic group compared to the control group. Additionally, levels of pH, lactic acid, TVB-N, counts of psychrophilic and mesophilic bacteria in arsenic (0.01 ppm)+propolis (10 ppm) group significantly reduced compared to arsenic group (p<0.05). In conclusion, propolis can affects some biochemical and microbiologic functions and quality in the fillet of carp exposed to arsenic.
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    Modulation of DMBA-induced biochemical changes by organoselenium compounds in. blood of rats
    (Natl Inst Science Communication-Niscair, 2007) Ozdemir, I.; Selamoglu, Z.; Ates, B.; Gok, Y.; Yilmaz, I.
    The protective role of two synthetic organoselenium compounds 1-isopropyl-3-methylbenzimidazole-2-selenone (SeI) and 1, 3-di-p-methoxybenzylpyrimidine-2-selenone (Sell) was examined against the 7,12-dimethylbenz[a]anthracene (DMBA)-induced changes in biochemical parameters in blood of rats. Albino Winstar rats (150-200 g body wt) were treated with single dose of DMBA (50 mg/kg body wt) and organoselenium compounds (25 mu mol/kg) for 4 weeks at two days internal. Blood was taken from the anaesthetized rats ventricle from their hearts for biochemical analysis. Administration of DMBA resulted in elevation of urea, uric acid and creatinine levels as well as AST, ALT and LDH activities and decrease in levels of total proteins, albumin and globulin. Set and Sell caused I significant (p<0.05) decrease ill Urea, uric acid and creatinine levels and alanine aminotransferase (ALT); aspartate aminotransferase; (AST) and lactate dehydrogenase (LDH) activities and significantly increased the levels of total protein and albumin (p<0.05). These organoselenium compounds are likely to be beneficial in human health.