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Öğe A COMPARISON OF VITAMIN D LEVELS IN PATIENTS WITH ACNE VULGARIS AND HEALTHY INDIVIDUALS(Springer London Ltd, 2017) Sarac, G.; Koca, T. T.; Sener, S.[Abstract Not Available]Öğe A comparıson of vıtamın d levels ın patıents wıth acne vulgarıs and healthy ındıvıduals(Sprınger london ltd, 236 grays ınn rd, 6th floor, london wc1x 8hl, england, 2017) Sarac, G.; Koca, T. T.; Sener, S.Öğe Delayed diagnosis of bullous pyoderma gangrenosum with acute myelogenous leukemia(Medknow Publications & Media Pvt Ltd, 2016) Sener, S.; Sarac, G.; Altunisik, N.; Bayindir, Y.Pyoderma gangrenosum (PG) is a rare, but serious neutrophilic dermatosis characterized by recurrent painful cutaneous ulcerations. It is commonly associated with inflammatory bowel disease, rheumatoid arthritis, and hematological malignancies. Because laboratory evaluations and histologic features of PG are nonspecific, diagnosis is based on the clinical features of the ulcer and requires exclusion of other conditions that cause such ulceration. The disease responds to glucocorticoids, immunosuppressives, and anti-inflammatory drugs. We present a 30-year-old man with acute myelogenous leukemia (subtype M5) and bullous PG. Treatment with high-dose prednisolone was successful.Öğe EFFECT OF 6-MONTH ISOTRETINOIN TREATMENT ON 25-HYDROXYVITAMIN D LEVELS IN PATIENTS WITH ACNE VULGARIS(Springer London Ltd, 2017) Sarac, G.; Koca, T. T.; Sener, S.[Abstract Not Available]Öğe Evaluation of hearing function in patients with lichen planus(Churchill Livingstone, 2020) Altunisik, N.; Koc, A.; Toplu, Y.; Sener, S.; Turkmen, D.; Sarac, G.; Durmaz, ILichen planus (LP) is a chronic, autoimmune, inflammatory disease. We believe that tympanic membrane and outer ear canal can be affected by the disease and since it is an autoimmune disease inner ear involvement may be seen. The aim of this study was to evaluate hearing functions in patients with LP. Thirty patients with LP and 28 healthy controls were involved in the study. Pure tone audiometry, tympanogram and Transient Evoked Otoacoustic Emissions tests were applied to the patients. When the airway hearing thresholds of the patient and control groups in the 125-8000 Hz frequency range were compared, statistically significant differences were found at 4000, 6000 and 8000 Hz frequencies in the right ear and at 125, 4000, 6000 and 8000 Hz frequencies in the left ear. In the LP patient group, 6 patients had sensorineural hearing loss, 3 patients had conductive hearing loss, and 2 patients had mixed hearing loss. Of the 3 patients with conductive hearing loss, 2 had cutaneous and 1 had both mucosal and cutaneous involvement. Of the patients with mixed hearing loss, 1 had cutaneous and 1 had both mucosal and cutaneous involvement. In patients with sensorineural hearing loss, 1 had mucosal, 3 had cutaneous, and 2 had both mucosal and cutaneous involvement. Sensorineural, conductive or mixed hearing loss can be observed in LP patients.Öğe Evaluation of the Dermatological Life Quality Index, sexual dysfunction and other psychiatric diseases in patients diagnosed with vitiligo with and without genital involvement(Wiley, 2021) Yucel, D.; Sener, S.; Turkmen, D.; Altunisik, N.; Sarac, G.; Cumurcu, H. B.Background Because skin lesions affect self-image, vitiligo affects an individual's emotional and psychological well-being, sexual life and relationships with other people. The literature contains a limited number of studies regarding the localization of vitiligo with respect to its effect on certain variables. Aim To investigate the effects of the presence or absence of genital involvement in vitiligo on sexual dysfunction, dermatological quality of life (QoL), and susceptibility to other psychiatric disorders such as anxiety and depression. Methods In total, 90 patients who were admitted to the dermatology outpatient clinic of a tertiary university hospital; the patients included 30 patients with vitiligo with genital involvement, 30 patients with vitiligo without genital involvement and 30 controls (HCs). All groups were evaluated with the Dermatological Life Quality Index (DLQI), Hospital Anxiety and Depression Scale (HAD), Arizona Sexual Experience Scale (ASEX) and Golombok-Rust Inventory of Sexual Satisfaction (GRISS). Results The HC groups exhibited lower total scores on the DLQI, HAD total score, ASEX and GRISS compared with the vitiligo groups (P < 0.05). No statistically significant difference was found between the vitiligo group with genital involvement and the vitiligo group without genital involvement in terms of DLQI, and total scores for HAD, ASEX and GRISS (P > 0.05). Conclusion The presence or absence of genital involvement in vitiligo did not have dissimilar effects on the individual's QoL, or their sexual and psychological state.Öğe Quality of life, emotion dysregulation, attention deficit and psychiatric comorbidity in children and adolescents with vitiligo(Wiley, 2021) Ucuz, I.; Altunisik, N.; Sener, S.; Turkmen, D.; Kavuran, N. A.; Marsak, M.; Colak, C.Background Vitiligo is an acquired pigmentation disorder, which can have a negative effect on patient quality of life (QoL). Aim To evaluate QoL and psychiatric comorbidity in paediatric patients with vitiligo. Methods In total, 30 patients aged 8-18 years who were diagnosed with vitiligo and 30 age- and sex-matched healthy controls (HCs) were included in the study. The Children's Depression Inventory, Screen for Child Anxiety Related Disorders, State-Trait Anxiety Inventory for Children and Child Somatization Inventory were completed for both patients and controls. The Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL) was administered to all patients by a child psychiatrist. Families were also asked to complete the Pediatric Quality of Life Inventory and Emotion Regulation Checklist for children. Results The K-SADS-PL evaluation showed that 90% of the patients in the vitiligo group had at least one psychiatric diagnosis, whereas this rate was 20% in the HCs (P < 0.001). There were statistically significant differences between vitiligo and HCs in terms of anxiety, state and trait anxiety scores (P < 0.05). Attention deficit and hyperactivity disorder (ADHD) was detected in 36.6% of the patients. Conclusion The most important finding of this study is that anxiety disorders are more prominent than depression in childhood vitiligo. Another important finding of this study is that the prevalence of ADHD is significantly higher than the normal population.Öğe Segmental tuberous sclerosis in a patient presenting as unilateral facial angiofibromas, periungual fibromas and Shagreen patch(Verduci Publisher, 2011) Sener, S.; Sasmaz, S.Tuberous sclerosis (TS) known as Epiloia and Bourneville's disease is an autosomal dominant inherited disorder that can affect many organ systems. Tuberous sclerosis has many forms of clinical presentation. Rarely, multiple facial angiofibromas of unilateral distribution have been reported. We describe a patient with unilateral facial angiofibromas, periungual fibromas and Shagreen patch.