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    Inter-observer compliance in the SurePath liquid-based cervicovaginal smears diagnosed with epithelial cell abnormality
    (2019) Baz, Vahide; Ozekinci, Selver; Harman Kamali, Gulcin; Sengiz Erhan, Selma
    Aim: To assess compliance among observers in the investigation of the liquid-based cervicovaginal smears that were reported epithelial cell abnormality in the Okmeydanı ERH Pathology laboratory. Material and Methods: 5,250 SurePath liquid-based cervicovaginal smears, which were sent by the pathology laboratory during the period of 5 months, were scanned. One-hundred and twenty-seven smears diagnosed with the epithelial cell abnormality were included in the study, and were reexamined by three pathologists. The Bethesda2001 system was used for evaluation. One of the experts had more experience in SurePath liquid-based cytology than the experience of the others. Results: There were significant differences between the three physicians because of the Friedman test (p = 0.000) that was applied for the comparison of the reports in 127 smears examined by three experienced experts in SurePath liquid-based cytology. In binary comparison with the Wilcoxon test that was applied to find out the differences among expert pathologists, there was no significant difference between the reports of the two expert pathologists (p = 0.366); however, it was found that there was a significant difference between the pathologist who had more experience and other specialist pathologists (p = 0.000). Conclusion: Moderate compliance was determined between pathologists 1 and 2, and low-level compliance was determined between pathologists 1-2 and 3.
  • Küçük Resim
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    Nightmare of a pathologist: Metastatic adenocarcinoma from breast to gastrointestinal system and gallbladder
    (2022) Sengiz Erhan, Selma; Hallac Keser, Sevinc; Sensu, Sibel; Karabiyik Altiok, Damla; Sari, Bahar; Alemdar, Ali
    Aim: Breast tumors usually metastasize to lymph nodes, bone, lung, liver and central nervous system, and rarely to gastrointestinal system (GIS) and gallbladder. In this study, we aimed to present and discuss our breast carcinoma cases with GIS and gallbladder metastases. Material and Methods: Clinicopathological findings of nine breast tumors with metastases to gallbladder and GIS were evaluated in our study. Results: The mean age was 51.2 years. Seven cases, five of which were invasive ductal carcinoma (IDC) and two invasive lobular carcinoma (ILC), had metastases to GIS. In these cases, metastatic foci were mostly observed in stomach, small intestine, sigmoid colon and rectum, respectively. The diagnosis of two cases with metastases to gallbladder was IDC. In two cases, one with gastric and other, with gallbladder metastases, lymph nodes were also involved. All cases died aside from an IDC with gallbladder metastasis and an ILC with gastric metastasis. Conclusion: Metastasis from a breast tumor should be taken into consideration particularly in cases with unknown primary. GIS and gallbladder, though rare, might be the metastatic foci of breast carcinomas.