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    Cutaneous fistulization of the hydatid disease: A PRISMA-compliant systematic review
    (Lippincott Williams & Wilkins, 2016) Bahce, Zeynep Sener; Akbulut, Sami; Aday, Ulas; Demircan, Firat; Senol, Ayhan
    Aim:To provide an overview of the medical literature on cutaneous fistulization in patients with hydatid disease (HD).Methods:According to PRISMA guidelines a literature search was made in PubMed, Medline, Google Scholar, and Google databases were searched using keywords to identify articles related to cutaneous fistulization of the HD. Keywords used were hydatid disease, hydatid cyst, cutaneous fistulization, cysto-cutaneous fistulization, external rupture, and external fistulization. The literature search included case reports, review articles, original articles, and meeting presentations published until July 2016 without restrictions on language, journal, or country. Articles and abstracts containing adequate information, such as age, sex, cyst size, cyst location, clinical presentation, fistula opening location, and management, were included in the study, whereas articles with insufficient clinical and demographic data were excluded. We also present a new case of cysto-cutaneous fistulization of a liver hydatid cyst.Results:The literature review included 38 articles (32 full text, 2 abstracts, and 4 unavailable) on cutaneous fistulization in patients with HD. Among the 38 articles included in the study, 22 were written in English, 13 in French, 1 in German, 1 in Italian, and 1 in Spanish. Forty patients (21 males and 19 females; mean agestandard deviation, 54.0 +/- 21.5 years; range, 7-93 years) were involved in the study. Twenty-four patients had cysto-cutaneous fistulization (Echinococcus granulosus); 10 had cutaneous fistulization (E multilocularis), 3 had cysto-cutaneo-bronchio-biliary fistulization, 2 had cysto-cutaneo-bronchial fistulization; and 1 had cutaneo-bronchial fistulization (E multilocularis). Twenty-nine patients were diagnosed with E granulosis and 11 had E multilocularis detected by clinical, radiological, and/or histopathological examinations.Conclusion:Cutaneous fistulization is a rare complication of HD. Complicated HD should be considered in the differential diagnosis of cases presenting with cutaneous fistulization, particularly in regions where HD is endemic.
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    Histopathological evaluation of percutaneous renal biopsies: A single center experience
    (2021) Kaya, Seyhmus; Gunay, Emrah; Yuksel, Enver; Senol, Ayhan; Ay, Nurettin
    Aim: The aim of this study was to examine the indications, demographic features and histopathological diagnosis category of renal biopsies evaluated at the Pathology Laboratory of the University of Health Sciences Diyarbakır Gazi Yasargil Training and Research Hospital. Materials and Methods: The information of 190 patients who underwent percutaneous renal needle biopsy between July 2017 and February 2020 was obtained from the approved final pathology reports. Results: 190 biopsies were performed. 60% (n=114) and 40% (n=76) of the biopsies were native and transplant, respectively. 59.5% of the patients were male. Four of the patients were under 18 years. The mean ages of the native and transplant biopsy groupes were 37±14, and 34±14, respectively. Proteinuria was the most common biopsy indication (79.5%).Nonspecific changes were the most common diagnosis of the native biopsies. It was followed by focal segmental glomerulonephritis (FSGS), membranous glomerulonephritis (MGN), and IgA nephritis (IgAN). The most common secondary cause of glomerulonephritis was lupus nephritis. Acute cellular rejection was the most common diagnosis of the transplant renal biopsies. Conclusion: Proteinuria was identified as the most common indication for biopsy. In the present study, the primary glomerular disease was FSGS while the secondary was lupus nephritis. With electron microscopic examination, it might be possible to decrease the number of patients who cannot be definitively diagnosed histomorphologically