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Öğe Evaluation of visceral adipose tissue thickness in precocious puberty(Verduci Publisher, 2023) Tasolar, S. D.; Sigirci, A.; Ciftci, N.; Cengiz, A.; Dogan, G. M.; Akinci, A.- OBJECTIVE: Although there is a relationship between earlier onset of puberty and increased adiposity tissue. Publications in the lit-erature on adiposis in patients with central pre-cocious puberty (CPP) and visceral fat thickness (VFT) have conflicting results. So, in this study, we aimed to evaluate the relationship between sexual maturation and obesity in the development of early puberty and to examine their relationship with pelvic sonographic parameters. PATIENTS AND METHODS: A total of 126 girls [patients - premature thelarche (PT) and CPP - and controls] were included in this study. Anthro-pometric and ultrasonographic evaluations were made by the same pediatric endocrinologist and pediatric radiologist, respectively. Pubertal stages were made according to the Tanner stages. Height, weight, and body mass index were measured as anthropometric measurements, and visceral, sub-cutaneous, and transabdominal fat thicknesses were measured in sonographic evaluation. RESULTS: The study population was divided in-to three groups: 44 healthy subjects to Group 1, 23 patients with PT to Group 2, and 59 patients with CPP to Group 3. When we evaluated the anthropo-metric and ultrasonographic parameters according to pubertal status, significant differences, especial-ly between Group 1 and Group 3, were observed in all data. In the multiple logistic regression analysis, the endometrial thickness (OR = 7.521, p < 0.001) and VFT (OR = 1.530, p < 0.001) were found to be in-dependent predictors of precocious puberty. CONCLUSIONS: It has been found that VFT and endometrial thickness measurements, which are evaluated quickly and accurately by USG, are im-portant predictors of prepubertal precociousness.Öğe The magnetic resonance imaging assessment of optic nerve sheath diameter in pediatric acute liver failure patients(Verduci Publisher, 2022) Dogan, G. M.; Sigirci, A.; Okut, G.; Cicek, E.; Dogan, S. M.; Yilmaz, S.; Arslan, A. K.OBJECTIVE: To evaluate the di-agnostic value of optic nerve sheath diameter (ONSD) using brain MRI in the pretransplantation period in the pediatric acute liver failure patients, and correlate the ONSD with clinical grade of hepatic encephalopathy (HE) and MRI findings. PATIENTS AND METHODS: Forty acute liver failure patients and 40 control group patients were retrospectively analyzed. The high signal intensities in T2W (T2-weighted image), FLAIR (Fluid Attenuated Inversion Recovery) and DWI (diffusion-weighted imaging) sequences were evaluated and ONSD were measured. The patients were grouped first into 5 according to their West Haven score, and HE grade 0 and grade 1 were accepted as low grade HE, HE grade 2, 3 and 4 were accepted as high grade HE. The patients were grouped to 2 according to the MRI findings as low grade and high grade MRI group. RESULTS: The mean value of ONSD was 6.0 +/- 1.80 and 4.94 +/- 1.27 in all the patients and in the control group, respectively. There was statistically significant difference between both the ONSD and the low grade-high grade HE groups (p=0.01), and between the ONSD and the low grade-high grade MRI groups (p<0.001). CONCLUSIONS: Although high ONSD values do not make the diagnosis of cerebral edema, it may cause suspicion in the early period. MRI can be helpful in the diagnoses of increased intracranial pressure like ultrasound. Our study is the first study to compare ONSD and MRI findings in addition to HE grades. The widespread use of MRI in children in recent years may help determine the normal range of ONSD values.Öğe Pre-operative Trans-thoracic Doppler Ultrasonography Evaluation and Intra-operative Manual Evaluation of the Left Internal Thoracic Artery in Patients with Type 2 Diabetes with Coronary Artery Disease(Sage Publications Ltd, 2011) Cihan, H. B.; Erbas, F.; Erdil, N.; Sigirci, A.; Battaloglu, B.; Yologlu, S.Patients with coronary artery disease, with (n = 25) and without (n = 59) type 2 diabetes, who were scheduled to undergo coronary artery bypass grafting were enrolled in this prospective study. The left internal thoracic artery (LITA) was assessed for graft suitability before surgery by trans-thoracic Doppler ultrasonography and during surgery by manual measurement. Significant differences were seen between pre-operative and intra-operative LITA blood flow rates and LITA diameters, and the values of each at the two time points showed significant correlation, suggesting that pre-operative measurements largely related to intra-operative conditions. The pre-operative and intra-operative LITA blood flow rates and LITA diameters were not significantly different between patients with and without type 2 diabetes. Pre-operative LITA blood flow was monophasic in three patients without diabetes and the LITA grafts of these patients were deemed unsuitable for implantation during surgery. It is concluded that type 2 diabetes does not seem to have a negative effect on the suitability of LITA grafts. In addition, trans-thoracic Doppler ultrasonography is an easy, cost-effective, reproducible and non-invasive examination method, which may help in the evaluation of LIMA function and contribute to graft selection.Öğe Spontaneous resolution of fetal dural sinus thrombosis following term delivery of a live infant(Wiley-Blackwell, 2012) Simsek, Y.; Oztanir, N.; Sigirci, A.; Celik, E.; Yilmaz, E.; Celik, O.; Onal, C.[Abstract Not Available]
