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    Assessment of pharyngeal airway volume in adolescent patients affected by bilateral cleft lip and palate using cone beam computed tomography
    (E H Angle Education Research Foundation, Inc, 2014) Celikoglu, Mevlut; Ucar, Faruk I.; Sekerci, Ahmet E.; Buyuk, Suleyman K.; Ersoz, Mustafa; Sisman, Yildiray
    Objective: To test the null hypothesis that there were no significant differences for pharyngeal airway volumes between the adolescent patients affected by bilateral cleft lip and palate (BCLP) and well-matched controls using cone beam computed tomography. Materials and Methods: The study sample consisted of 16 patients (11 female and 5 male; mean [SD] age 14.1 [2.1] years) affected by BCLP and 16 patients (10 female and 6 male; mean [SD] age 13.4 [2.0] years) as age- and sex-matched control group. Craniofacial measurements and pharyngeal airway dimension, area, and volume measurements of patients in both groups were calculated and statistically examined using Student's t-test and multiple linear regression analyses. Results: Statistically significant differences were found between the BCLP and control groups for SNB (P <.05), SN-GoGn (P <.05), Co-A (P <.05), PAS (P <.01), minAx (P <.01), and oropharyngeal airway volume (P <.05). The most predictive variables for oropharyngeal airway volume were found as PAS (r =.655 and P =.000) and minAx (r =.787 and P =.000). Conclusions: The null hypothesis was rejected. Oropharyngeal (P <.05) and total (P>.05) airway volumes were found to be less in the BCLP group, and thus the treatment choice in these patients should have positive effects on the pharyngeal airway.
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    Facial soft-tissue thickness in patients affected by bilateral cleft lip and palate: A retrospective cone-beam computed tomography study
    (Mosby-Elsevier, 2014) Celikoglu, Mevlut; Buyuk, Suleyman K.; Sekerci, Ahmet E.; Ersoz, Mustafa; Celik, Salih; Sisman, Yildiray
    Introduction: The purposes of this study were to evaluate the facial soft-tissue thicknesses and craniofacial morphologies of patients affected by bilateral cleft lip and palate (BCLP) and to compare the findings with a well-matched control group without any clefts using cone-beam computed tomography. Methods: The study sample consisted of 40 retrospectively and randomly selected patients divided into 2 groups: a BCLP group (20 patients; mean age, 13.78 +/- 3.20 years) and an age-and sex-matched control group without clefts (20 patients; mean age, 13.94 +/- 2.52 years). Craniofacial and facial soft-tissue thickness measurements were made with cone-beam computed tomography. The Student t test and multiple linear regression analyses were performed for the statistical evaluations. Results: The BCLP group had an increased SN-MP angle (P = 0.003), a decreased Co-A (P = 0.000), and retruded maxillary (P = 0.000) and mandibular (P = 0.026) incisors. In addition, patients affected by BCLP had statistically significantly decreased thickness measurements for the variables subnasale (P = 0.005) and labrale superior (P = 0.026) compared with the controls. The most predictive variables were found at U1-SN (r = 0.417, P = 0.004), IMPA (r = 0.368, P = 0.010), and ANB (r = -0.297, P = 0.031) for subnasale and U1-SN (r = 0.284, P = 0.038) for labrale superior. Conclusions: The BCLP group showed greater vertical growth, greater retrusion of the maxilla and the maxillary and mandibular incisors, and decreased subnasale and labrale superior thicknesses compared with the well-matched controls without clefts. These differences should be taken into account when planning orthodontic and orthognathic surgery treatment for those patients.