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    Hyperglycemia and hyponatremia in predicting the recurrence of febrile convulsions
    (2021) Surucu Kara, Ilknur
    Aim: The most common seizure type in childhood is febrile convulsion, which is likely to recur due to many risk factors. This study aimed to evaluate serum sodium and glucose levels in patients who had a febrile convulsion and investigate the relationship between these values and recurrent seizures.Materials and Methods: The medical records of patients presenting to our hospital with the diagnosis of febrile convulsion between 2013 and 2018 were investigated. Patients with high-risk factors for recurrence were excluded. According to the reference ranges of our laboratory, for glucose, 101-149 mg/dl as mild-to-moderate stress hyperglycemia, above 150 mg/dl as severe stress hyperglycemia; for sodium, below 134 mmol/L as hyponatremic.Results: Of the 90 patients, 51 were boys, and 39 were girls. Without recurrent convulsions with recurrent convulsions (first-last): The mean age was 27.2±12.7 months / 27.4 ± 11.3 months-30.5±12.4; the mean serum glucose level was 129.1±37 mg/dl/130 ±37.5 mg/dl-124 ± 34 mg/dl; the mean serum sodium level was 134.07±3.05 mmol/L 134.4 ± 2.6 mmol/L-133.8 ± 2.9mmol/L. The glucose level was 60-100 mg/dl in 14/5 cases, 101-149 mg/dl in 39/10 cases, and above 150 mg/dl in 16/6 cases; the sodium level was 135-150 mmol/L in 29/10 cases, 135 mmol/L in 40/11 cases.Conclusion: Febrile convulsion is in most cases present with hyponatremia and hyperglycemia, but this cannot be a predictive marker of seizure recurrence.
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    The Relationship Between Vitamin-D Deficiency and Protein Oxidation Among Obese Children
    (Taylor & Francis Inc, 2023) Surucu Kara, Ilknur; Mertoglu, Cuma; Siranli, Guelsah; Arslan, Yusuf Kemal; Gok, Gamze; Erel, Ozcan
    Aim: The aim of the study is to examine the relationship between obesity, Vitamin-D deficiency, and protein oxidation. Methods: Thiol-disulfide homeostasis, Vitamin-D, ischemia modified albumin, insulin, and lipid levels were compared among obese, pre-obese and normal-weight healthy children. Results: A total of 136 children (69 boys and 67 girls) were included in the study. The vitamin-D levels of obese children were lower than those of pre-obese and normal weight (p < 0.05). In the normal weight group, total thiol and native thiol were lower in the pubertal period than in adolescence; were higher in those with sufficient Vitamin-D level than those with insufficient and deficient Vitamin-D (p < 0.05). Vitamin-D level was lower in pre-obese girls than boys (p < 0.05). Those with high triglycerides had high disulfide/total thiol, disulfide, and disulfide/native thiol and low native thiol/total thiol (p < 0.05). Conclusion: Thiol-disulfide homeostasis is negatively affected by low vitamin D levels, pubertal period and high triglyceride levels.