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Öğe The affecting factors and prevalence rate of sick building syndrome in healthcare workers(2023) Karadag, Muge Otlu; Ercin, Seval Müzeyyen; Türkkan, Sinan; Aytemur, Zeynep Ayfer; Hacıevliyagil, Süleyman SavaşSick building syndrome (SBS) is defined as symptoms that occur while living or working in a certain building but disappear after moving away from the environment. In this study, we aimed to determine the effects of indoor air pollutants on the health of employees, the prevalence of SBS in healthcare workers at the university hospital, its relationship with environmental and personal factors and the respiratory system. A questionnaire was applied to 951 healthcare workers who agreed to participate in the study. Having at least one general, one mucosal and one skin symptom every week in the last 3 months was accepted as SBS. Temperature, CO and CO2 levels and relative humidity were measured in different areas of the hospital. The prevalence of SBS was 62.1%. There was a statistically significant relationship between SBS and having a chronic disease (p<0.0001), continuous drug use (p=0.005) and the evaluation of the environment as warm (p=0.042). Having a chronic disease (OR=0.426; 95% CI, 0.228–0.797), the environment often being too warm (OR 0.218; 95% CI, 0.084–0.567) or occasionally too bright (OR=0.300; 95% CI, 0.158–0571) and diagnosed by a doctor due to symptoms (OR=3.209; 95% CI, 1.529–6.731) was found to be significant in forward variable selection method and binary logistic regression analysis. In our study, a relationship was found between physical factors such as temperature, humidity and CO2 level of the environment and personal factors such as stress, chronic disease and SBS. SBS can be prevented by control at the source as well as by administrative and engineering interventions among the employees.Öğe KOAH hastalarının 35 yaş ve üzeri birinci derece yakınlarında KOAH prevelanslarının araştırılması(İnönü Üniversitesi, 2012) Türkkan, SinanMerkezimizde Kronik Obstrüktif Akciğer Hastalığı (KOAH) tanısı konularak poliklinik veya serviste yatarak takip ve tedavileri yapılan hastaların birinci derece yakınlarında (kardeş, anne-baba, çocuklar) KOAH prevelansını araştırmak. Materyal-Metod: Çalışmaya merkezimizde anemnez, fizik muayene, SFT ve grafi bulguları ile KOAH tanısı konulmuş 78 hasta ve bunların 35 yaş ve üzeri 139 yakını alındı. Hasta ve hasta yakınlarının sosyodemografik kayıtları alındı. Hasta yakınlarına SFT yapıldı, alfa-1 antitripsin enzim düzeyi ölçüldü. Bulgular: Çalışmaya alınan, SFT yapılabilen ve alfa-1 enzim düzeyleri normal olan 129 hasta yakınının 24'ünde (%18.6) FEV1/FVC<0.7 saptandı. FEV1/FVC<0.7 saptanan kişilerin 7/24 (% 29.2) bayan idi ve % 90'ında sigara öyküsü vardı. İndeks hastalarımızın ve hasta yakınlarının büyük çoğunluğunda (sırasıyla yaklaşık %75 ve % 50) biyomass maruziyeti olması ve hasta yakınlarının yaklaşık ¾'ünde sigara hikayesi olması dikkat çekici idi. Hasta yakınlarını 40 yaş ve üzeri ve sigara öyküsü olanlar diye ayırdığımızda ise bu grupta yaklaşık % 25'lik KOAH oranı saptandı. Sonuç: KOAH hastalarının birinci derece yakınların KOAH prevalansı artmış görünmektedir. Sigara dumanı ile birlikte özellikle bölgemiz için biyomas maruziyeti en önemli risk faktörleri olmaya devam etmektedir.Öğe The relationship between serum gamma glutamyl transferase levels and obtructive sleep apnea severity(2022) Geçkil, Ayşegül Altıntop; Ermis, Hilal; Gülbaş, Gazi; Türkkan, Sinan; Sağmen, Seda BeyhanObstructive sleep apnea (OSA) can cause local and systemic inflammation due to hypoxia, asphyxia, hypercapnia, respiratory acidosis. Searching for new inflammatory markers in OSA may facilitate the prediction of OSA-related conditions. Therefore, we aimed to investigate the relationship between OSA severity and serum gamma glutamyl transferase (GGT) levels. In the study, the GGT levels of the patients were compared according to the degree of OSA determined by polysomnography. The patients' demographic, polysomnographic, and laboratory parameters were evaluated with SPSS 25 program. A total of 500 patients, 299 (59.8%) male and 201 (40.2%) female, were included in the study. The mean age of the patients was 47.9±13.1, and body mass index (BMI) was 32.2±6.6. There were 98 (19.6%) patients in the control group, 100 (20%) in the mild OSA group, 103 (20.6%) in the moderate OSA group, and 199 (39.8%) in the severe OSA group. When the BMI and desaturation index of the groups were compared, there was a statistical difference (respectively, p<0.001, p<0.001). When the serum GGT values of the groups were compared, the GGT values of the moderate and severe OSA groups were higher than the control group (respectively, p=0.011, p=0.001), and there was a statistically significant difference between the groups (p=0.001). There was a positive correlation between GGT levels and BMI (r=0.151, p=0.010). There was a positive correlation between GGT levels and age (r=0.615, p=0.029). As a result of our study, a relationship was found between high GGT levels and the severity of OSA. Serum GGT level may be a promising biomarker to identify OSA patients at high risk.Öğe A Right Atrial Myxoma Mimicking Pulmonary Embolism: A Case Report(Ömer K.,Hilal E.,Sinan T.,Zeynep Ayfer A.,Tamer B.,Nusret A. (2014).A Right Atrial Myxoma Mimicking Pulmonary Embolism: A Case Report, Solunum, İnönü Üniversitesi, Malatya., 2014) Kaya, Ömer; Ermiş, Hilal; Türkkan, Sinan; Aytemur, Zeynep Ayfer; Baysal, Tamer; Açıkgöz, NusretAbstract Myxoma is the most common primary tumour of the heart. Approximately 75% of primary cardiac myxomas are located in the left atrium and tend to be sporadic. Myxomas are rarely asymptomatic and presenting symptoms may sometimes be confused with respiratory diseases. A 29-year-old male patient was admitted to our outpatient clinic with shortness of breath and chest pain. In the thoracic computed tomography, which was performed for the pre-diagnosis of pulmonary embolism, a hypodense space-occupying lesion, approximately 8X4 cm in size, with irregular margins that did not show contrast enhancement in the right atrium and right ventricle, was identified. The patient, whose diagnosis of myxoma was confirmed by echocardiographic examination, underwent excision of the intracardiac mass. The present case was deemed to be suitable for presentation since the myxoma was located in the right atrium and right ventricle, as well as to remind that an underlying cardiac pathology should be considered in patients presenting with respiratory symptoms. Keywords: Right atrial myxoma, cardiac tumour, pulmonary embolism
