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Öğe Alopesi areatalı hastalarda serum bilirubin, ürik asit ve albumin düzeyleri(2020) Altunışık, Nihal; Türkmen, DursunAmaç: Alopesi areata (AA), saçlı deride skar bırakmayan kıl kaybı ile karakterize, inflamatuar birhastalıktır. Son dönemlerde inflamatuar ve otoimmun hastalıkların patogenezinde düşük antioksidandüzeyleri ve oksidatif stresin rol oynadığını gösteren çalışmalar bulunmaktadır. Çalışmadakiamacımız, vücuttaki antioksidan durumu yansıtan serum bilirubin, albümin (Alb) ve ürik asit (ÜA)düzeylerinin alopesi areata etiyopatogenezinde rolünü değerlendirmektir.Gereç ve Yöntem: Çalışmaya dermatoloji kliniğine başvuran 62 AA hastası ile yaş ve cinsiyet olarakbenzer 61 sağlıklı kontrol grubu alındı. Her iki grupta, serum total bilirubin (Tbil), direkt bilirubin (Dbil),indirekt bilirubin (İbil), ÜA ve Alb düzeyleri ölçüldü.Bulgular: Çalışmaya 62 alopesi areata hastası (50 erkek, 12 kadın) ve 61 kontrol hastası (48 erkek,13 kadın) dahil edildi. İki grup arasında yaş ve cinsiyet açısından istatistiksel olarak anlamlı bir farkyoktu. Alopesi areatalı hastalarda serum Tbil, İbil, ÜA ve Alb değerleri kontrol grubuna göre dahadüşüktü, fakat istatistiksel olarak anlamlı bir fark yoktu.Sonuç: Alopesi areatalı hastalarda serum Tbil, İbil, ÜA ve Alb değerlerinin kontrol grubuna göre dahadüşük olması bize vücuttaki antioksidan durumu yansıtan serum bilirubin, albümin ve ürik asitdüzeylerinin alopesi areata etiyopatogenezinde rolü olabileceğini düşündürmektedir. Bununla birlikteistatistiksel olarak anlamlı düzeyde düşüklük saptanmaması nedeniyle daha geniş olgu serileri içerençalışmalara ihtiyaç olduğuna inanmaktayız.Öğe Cutaneous findings in children and adolescents with attention deficit and hyperactivity disorder(2020) Altunışık, Nihal; Ucuz, İlknur; Türkmen, DursunAim: Attention Deficit and Hyperactivity Disorder (ADHD) is the most frequently diagnosed psychiatric disorder in children. Only one study was found in literature which examined cutaneous findings in ADHD so far. The aim of the present study is to evaluate the cutaneous findings of children and adolescents diagnosed with ADHD and to compare the incidence of these findings with healthycontrols.Material and Methods: Forty-six patients diagnosed with ADHD according to The Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-V) criteria and 50 healthy controls with no ADHD symptoms that had similar characteristics to the patient group in terms of sociodemographic characteristics such as age and gender were included in the study. All the patients underwent whole body dermatological examination and pathological findings in the skin, hairy skin and nails in the patient and control group were recorded.Results: The most common finding in the patient group was found as onychophagy and/or periungual skin biting with a rate of 76.1%. In addition, statistically significant difference was found between the two groups in terms of xerosis, prurigo and allergy history.Conclusions: It is important to be careful in terms of cutaneous findings that may accompany ADHD in terms of both early treatment and also for preventing possible complications. In addition, determination of these findings will guide future studies in terms of identifying the common aetiology of ADHD and some cutaneous diseases.Öğe Evaluation of the level of knowledge, source of information, application story and satisfaction about dermocosmetic procedures in Turkish society through a web-based questionnaire(2023) Türkmen, Dursun; Karatoprak, Hacer Vural; Altunışık, Nihal; Özbey, RafetAim: There have been very important advances in the field of dermato-cosmetology in recent years. Due to the advances in cosmetology, the emergence of new products, the emergence of new laser devices, the interest of patients in cosmetological applications has increased. We aim to investigate the knowledge and experience of our society about cosmetic procedures, the frequency of the procedures, and the satisfaction rates. Methods: Sociodemographic characteristics such as age, gender, occupation, and monthly income of all individuals participating in the survey were recorded. The first dimension of the questionnaire includes demographic characteristics, and the second dimension includes questions about procedures. Results: The most common dermo-cosmetic application known to the participants was laser epilation (56.3%). The most common sources of information are social media and the internet. While 57.5% of the participants stated that they did not have any cosmetic application, the most frequently applied cosmetic procedure was laser epilation with 27.7%. 40.7% of the participants had cosmetic applications to look young and beautiful. Participants had the procedure performed most frequently at the beauty center with 51.6%. Conclusion: According to the results of our survey, a significant part of our society obtains information about dermocosmetic applications from social media and internet. It has been determined that cosmetic applications are still made intensively by people who are not physicians. The society needs to be properly informed about this issue.Öğe Psoriasis hastalarında Helicobacter pylori enfeksiyonunun rolü(İnönü Üniversitesi, 2010) Türkmen, DursunPsoriasis, sık görülen, kronik, inflamatuvar ve hiperproliferatif bir deri hastalığıdır. Psoriasisin tetiklenmesinde enfeksiyon hastalıkları özellikle beta hemolitik streptokoklar önemli rol oynayabilmektedir. Bu bakımdan gram-negatif eğri veya spiral bir bakteri olan H.pylori'nin psoriasisin oluşmasında rolü olup olmadığının belirlenmesi amaçlanmıştır. Gereç ve yöntem: Çalışmaya Temmuz 2009?Aralık 2009 tarihleri arasında İnönü Üniversitesi Tıp Fakültesi Dermatoloji Polikliniğine başvuran klinik olarak psoriasis tanısı almış 56 hasta (ortalama yaş, 38.43±14.08 yıl; 32 erkek, 24 kadın) dahil edildi. Kontrol grubu olarak da, psoriasis hastalığı ve H.pylori ile ilişkili dermatolojik hastalığı olmayan 57 hasta (ortalama yaş, 37.9±13.73 yıl; 26 erkek, 31 kadın) çalışmaya dahil edildi. Tüm hastalar ve kontrol grubunda H.pylori araştırmak için ÜNT yapıldı. Bulgular: 56 psoriasisli hastanın 38'inde (%67.9) ve 57 kontrol hastasının 38'inde (%66.7) ÜNT pozitif saptandı. Psoriasis hastaları ve kontrol grubu arasında ÜNT pozitifliği yönünden anlamlı bir fark yoktu (p=0.89). Tırnak psoriasisi olan 33 hastanın 24'ünde (%72.7) ÜNT pozitif sapatanırken, tırnak tutulumu olmayan 23 hastanın 14'ünde (%60.9) ÜNT pozitif bulundu (p=0.35). GİS şikayetlerinden reflü şikayeti olan tüm psoriasis hastalarında ÜNT pozitif saptandı (p=0.005). Psoriasis tipine göre ÜNT pozitiflik oranları: plak, 34/46 (%73.9); guttat, 4/7 (%57.1); eritrodermik, 0/1 (%0); püstüler, 0/1 (%0); palmoplantar, 0/1 (%0) idi. Sonuç: Plak psoriasiste H.pylori enfeksiyonunun tetikleyici bir faktör olduğu yönünde bulgu elde edilemedi. Çalışmalarda palmoplantar püstüler psoriasiste H.pylori enfeksiyonunun rol oynadığını bildiren yayınlar vardır. Bu nedenle H.pylori enfeksiyonunun psoriasisin tetiklenmesinde rolü olup olmadığını belirlemek için, duyarlılığı ve özgüllüğü daha yüksek olan yöntemlerle ve daha geniş serilerde çalışma yapılması uygun olabilir.Öğe A rare cause of acute generalized exanthematous pustulosis (AGEP); paracetamol ingestion(2017) Türkmen, Dursun[Abstract Not Acailable]Öğe A rare manifestation of giant cell arteritis: Bilateral scalp necrosis(2022) Marsak, Mücahit; Türkmen, Dursun; Altunisik, Nihal; Yolbaş, Server; Şener, Serpil; Özgül, Ayşegül; Yıldırım, İ. OkanThis study investigated the anxiety and depression levels in hospitalized healthy pregnants and pregnants with gestational diabetes mellitus (GDM) before the cesarean section. This case control study included 64 healthy pregnant (control) and 26 pregnants with GDM (case). Patients were assessed with the form of a socio-demographic and clinical characteristic and Hospital Anxiety Depression Scale (HADS). The mean age was 35.5±5.1 years in the case group and 29.4±4.3 in the control group. There was a significant difference between pregnant women with GDM and healthy pregnant in terms of total anxiety, total depression, psychomotor agitation, restlessness, laughing and seeing funny things, and being cheerful. 21% of the pregnant with GDM and 15% of the healthy pregnant had anxiety. Also, 34% of the pregnant with GDM and 23% of the controls had depression. Anxiety and depressive symptoms should be considered for hospitalized pregnant women with GDM before the cesarean section.Öğe Retrospective analysis of the frequency and variety of skin lesions in patients diagnosed with sarcoidosis and examined by dermatology in a tertiary health care facility(2023) Türkmen, Dursun; Kılıc, Talat; Karatoprak, Hacer VuralAim: The aim of this retrospective study is to examine the frequency and clinical features of skin lesions in patients with sarcoidosis and to compare them with the literature. Materials and Methods: The files of patients diagnosed with sarcoidosis in the last 10 years in our hospital were reviewed retrospectively. Age, gender, age at diagnosis, dermatology consultation or dermatological examination findings were recorded for all patients. Results: Thirty (69.8%) of the patients diagnosed with sarcoidosis were female and 13 (30.2%) were male. The mean age was 49.7 ± 12.2. When the patients are grouped according to the age ranges at which they are diagnosed, there are 1 (%2.3) patient between the ages of 10-19, 4 (%9.3) patients between the ages of 20-29, 6 (%13.9) patients between the ages of 30-39, 16 (%37.2) patients between the ages of 40-49, 8 (%18.6) patients between the ages of 50-59 and 8 (%18.6) patients over the age of 60. The mean age at which female patients were diagnosed with sarcoidosis was 47.56±12.85, and the mean age at which male patients were diagnosed with sarcoidosis was 41.86±13.81 years. The mean follow-up period of the patients was 4.0±3.1 years. Thirty-one (72.1%) of all patients were examined in dermatology. Dermatological findings including erythema nodosum were detected in 8 (18.6%) patients. Conclusion: Sarcoidosis is a multisystemic disease that can progress with various clinical findings and should be considered in the differential diagnosis with its frequent or rare findings. In this study, in which the data of patients diagnosed with sarcoidosis in the last 10 years in our hospital were evaluated, our findings were generally similar to the literature data.
