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    Assessment of atrial conduction time in patients with behçet's disease
    (Sociedade Portuguesa de Reumatologia, 2014) Cansel M.; Yagmur J.; Taşolar H.; Karincaoglu Y.; Ermis N.; Acikgoz N.; Bayramoglu A.
    Objective: Behçet's disease is characterized by increased inflammatory activity, and there there might be an increased risk of atrial arrhythmia in patients with this disease. Our study is aimed to evaluate a novel method of measuring atrial electromechanical features expressed as interatrial and intraatrial electromechani - cal delay by tissue Doppler echocardiography in patients with Behçet's disease. Methods: We evaluated 57 patients (mean age: 36.3±12.1 years) with Behçet's disease and 34 sex and age matched healthy volunteers (mean age: 38.4±8.6 years) as control group. P-wave dispersion (PWD) was calculated from the 12-lead surface ECG, interatrial and intraatrial electromechanical delay were measured by tissue Doppler imaging and conventional echocardiography. Results: Interatrial electromechanical delay and intraatrial electromechanical delay were prolonged in patients with active Behçet's disease compared with the patients with inactive disease and the controls (p<0.0001, p<0.0001, p=0.013 and p=0.001, respectively). Erythrocyte sedimentation rate and high-sensitivity C-reactive protein values of of patients with active Beh - çet's were significantly higher than those with inactive Behçet's disease and the controls (p<0.0001 and p<0.0001, respectively). High-sensitivity C-reactive protein and erythrocyte sedimentation rate were correlated with interatrial electromechanical delay in patients with Behçet's disease (r=0.44, p=0.001 and r=0.64, p<0.0001, respectively). Conclusions: The prolongation of atrial electrome- Mehmet Cansel1, Julide Yagmur1,Hakan Tasolar1, Yelda Karincaoglu2,Necip Ermis1,Nusret Acikgoz1, Adil Bayramoglu1, Omur Otlu1 ,Ferhat Eyyüpkoca1, Hasan Pekdemir1, Ramazan Ozdemir1 chanical conduction might be related with changes in structure and electrophysiological properties of the atrial myocardium or the conduction system in patients with active Behçet's disease.n time in patients with Behçet's disease.